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Tag: "fundamental" at biology news

U. Iowa researchers improve Huntington's disease symptoms in mice

...rence gives us the first opportunity to attack the fundamental problem and reduce protein expression from the disease gene," said Beverly L. Davidson, Ph.D., the Roy J. Carver Chair in Internal Medicine and UI professor of internal medicine, physiology and biophysics, and neurology. "Our study is the first demon...

Researchers Identify Cause of Early Bird Sleep Disorder

... Nature. Such studies may help unravel some of the fundamental mysteries of how circadian rhythms are established and maintained in creatures that have evolved along very different paths. As for the affected individuals, Ptacek said most are able to live normal lives, and some are proud of being able to arise b...

Second messenger NAADP shows fast, dose-related impact on satiety cycle

...ts, which range from annoying to lethal. "The most fundamental answer to solve safety and other issues," Yamasaki said, "is increasing the specificity of a drug, and NAADP could provide a key in the area of obesity." In another therapeutic arena, she notes, Viagra is the world's most successful and recognized s...

High fidelity keeps human DNA assembly line humming

...ntrol things like viral infections and tumors this fundamental process has to be understood in every detail. This is basic science, but basic science with practical application." Burton and his team study how RNA is made from a DNA template. DNA is the genetic material that holds the blueprint for life. DNA dic...

Team Invents Device For Weighing Individual Molecules

...osition, these tiny tuning forks ring at their own fundamental frequency of mechanical vibration, although at suc...e very early stages of cancer," Roukes says. "The fundamental problem with identifying these proteins is that one must sort through millions of molecules to make ...

How exactly does the brain control breathing?

...ing of exactly how the brain controls breathing is fundamental to the treatment of respiratory disorders. We know that breathing is an automatic rhythmic process that persists without conscious effort whether we are awake or asleep, but the question that has intrigued many scientists for well over 100 years is w...

Scientists discover global pattern of big fish diversity in open oceans

...ke snake mackerel and pelagic stingrays. This is a fundamental change in the world's oceans." To understand what creates these patterns of diversity, the scientists collaborated with oceanographers to examine different open ocean "habitat" features. Sea surface temperature and the level of oxygen in the water w...

MIT engineers an anti-cancer smart bomb

...ng Division and leader of the research team. "The fundamental challenges in cancer chemotherapy are its toxicity to healthy cells and drug resistance by cancer cells," Sasisekharan said. "So cancer researchers were excited about anti-angiogenesis," the theory that cutting off the blood supply can starve tumors ...

UCR chemist part of team identifying new areas of gene regulation

...acetylation, a modification of the protein, play a fundamental role in the regulation of gene activation and repression. The key findings of the current paper were the discovery of this acetylation at the core of the histone, rather than at the proteins' ends, which are where most gene regulation is thought to ...

Mechanism for the captation of nutrients in plants- unknown to date

...ocesses of captation This discovery breaks with a fundamental dogma in basic plant science holding that all substances penetrate the interior of the cell through the participation of specific transporters present in the plasma membranes - a model implying that, if hundreds of substances enter vegetable cells an...

Major advance made on DNA structure

...of this biological blueprint for life. One of the fundamental problems in biochemistry is to predict the structu...epair itself ?a vital biological function. A more fundamental understanding of DNA structure and its relationship to genetic sequences, researchers say, helps set...

Anthrax inhibitors identified by Burnham team

... to LF. This is very important as selectivity is a fundamental prerequisite for a drug to be safe for use in humans. Three lead compounds where tested in mice infected with anthrax spores, in combination with the antibiotic Ciprofloxacin. The survival rate for mice treated with each of the compounds tested in t...

Going To Extremes To Improve Human Health

... perceived as work hazards, but fatigue often is a fundamental cause of accidents and injuries," Minson said. Minson's work, which pertains to a range of disease conditions such as diabetes, involves uncovering the neural and vascular interactions in the skin during environmental heat stress. In the effort to u...

Size matters: Preventing large mammal extinction

... (IoZ) and Imperial College London have identified fundamental new approaches to improve the success of large mammal conservation. Published today in the journal Science, the largest study of its kind analyses key factors linked to the extinction of mammals. "Conservation biologists have always known that large...

Researchers track down cause of a disfiguring bone disorder

...range regulatory elements. "Our study addresses a fundamental issue with regard to the majority of the human gen...ave clinical relevance in addition to addressing a fundamental problem in genomics." Working with Loots on the study were Jessie Chang and Nicole Collette of Lawr...

Endocannabinoids ?the brain's cannabis ?demonstrate novel modes of action to stress

...onary terms, and they govern behaviors that are of fundamental importance to most species." ...

Promiscuous Catalytic Activity Possessed by Novel Enzyme Structure

...an independent nonprofit organization dedicated to fundamental discoveries in the life sciences, the improvement of human health and the training of future generations of researchers. Jonas Salk, M.D., whose polio vaccine all but eradicated the crippling disease poliomyelitis in 1955, founded the Institute in 19...

Stem cell training program to make its Stanford debut

...an independent nonprofit organization dedicated to fundamental discoveries in the life sciences, the improvement of human health and the training of future generations of researchers. Jonas Salk, M.D., whose polio vaccine all but eradicated the crippling disease poliomyelitis in 1955, founded the Institute in 19...

New Scripps Oceanography project to study sediments and ecosystem restoration in Venice lagoon

...multifaceted scientific program aimed at providing fundamental information about the effects of sediment transloc...parameters. Deheyn says that such an analysis is a fundamental precaution. "In SIOSED we will be extracting cores about two meters deep, and that could take us se...

Fruit fly studies open new window on cancer research

...uit flies may not seem an immediate priority, only fundamental research such as this can provide us with the understanding that leads to new applications. New treatments for illnesses such as cancer will only be found as we increase our knowledge of basic biological processes." ...

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