Navigating an integrated yeast network
...o biological phenomena and may help represent more fundamental network design principles than do simple motifs. ...r detailed network reconstruction and to elucidate fundamental organizational principles of biological networks." This press release is based on the following ar...Canadian youth 4th highest in international obesity study
...ssen. "Physical activity interventions should be a fundamental component of health campaigns aimed at reducing the global obesity epidemic." ...Study reveals new technique for fingerprinting environmental samples
...an genome. "EGT fingerprints may be able to offer fundamental insights into the factors impacting on various environments," said DOE JGI Director, Eddy Rubin, who led the research team. "With EGTs we don't actually need a complete genome's worth of data to understand the functions required of the organisms livi...Cooperation is key—a new way of looking at MicroRNA and how it controls gene expression
... discovery that sheds light on an area of research fundamental to everything from the normal processes that gover...e regulation of gene expression is one of the most fundamental tasks of every cell in the body because many of our genes encode proteins that may only be needed oc...Insight into DNA's 'weakest links' may yield clues to cancer biology
...t may offer a useful model system for studying the fundamental properties of so-called DNA fragile sites, providing new insight into the chromosomal instability found in cancer cells, said the researchers. "If you look at solid tumors in humans, you see that the chromosomes of cancer cells exhibit incredible in...Marine sponge yields nanoscale secrets
...t on the planet technologically. Silicon chips are fundamental components of computers and telecommunications dev...nstead, the scientists expect that by learning the fundamental mechanism used in nature, that mechanism could be translated into a practical and low-cost manufactu...One gene links newborn neurons with those that die in diseases such as Alzheimer's
...urprise to the researchers. They set out to answer fundamental questions about the small number of brain neurons that can be replaced when they die: Are these cells similar to other neurons that are not replaced in adult life? Or, in terms of which genes are "turned on," are they marked as transient? Nottebohm'...To sea or not to sea: When it comes to salmon sex, size sometimes doesn't matter
...ded by strays since then. Thus straying is just as fundamental an attribute of salmon as homing," he says. "Perhaps the offspring should be called strays only if they are unsuccessful when it comes time to reproduce, and colonists if they are successful." From an evolutionary perspective, a mixture of homing a...Signs of aging: Scientists evaluate genes associated with longevity
...Many processes involved in nematode aging may have fundamental and analogous roles in humans," Dr. Brooks-Wilson explains. "The human orthologs of some gene family members identified in this study have been associated with human age-related diseases." SAGE involves the isolation of short gene-specific sequence ...Researchers make surprise discovery that some neurons can transmit three signals at once
...n, we realized that this could explain a number of fundamental questions," explained Karl Kandler, Ph.D., associate professor of neurobiology at the University of Pittsburgh School of Medicine, and the study's senior author. "These findings shed new light on how inhibitory synapses evolve and are assembled into...Researchers develop assay that could be applied to drug screening
... is clathrin mediated endocytosis (CME). CME is of fundamental importance for many cellular activities including receptor down-regulation, nutrient uptake and maintenance of signal transmission across nerve cell junctions. Mis-regulation of CME has been implicated in some types of cancer and neuro-degenerative d......eractions between DNA and the enzyme, which are of fundamental importance for understanding cell division. DNA consists of two long strands joined together by pairs of bases. Both strands wind around each other in the form of a double helix with the base pairs acting as the 'stairs' in a staircase. The sequence...Scripps scientists find potential for catastrophic shifts in Pacific ecosystems
...a from the 20th century. "Finding nonlinearity is fundamental for understanding and managing changes in ecosystems," said Lucas of the Biological Oceanography Curricular Group at Scripps. "In the North Pacific ecosystem, nonlinearity means that different sets of biological growth rules will apply in each differ...Gene keeps neural cells on correct developmental path
...tem cell to differentiated neuron. It also reveals fundamental details of how stem cells retain developmental pla...und this problem. Unexpectedly, they also revealed fundamental ways in which stem cells remain plastic. "This paper is like a whole story, beginning with the birt......ls could be an informative model for investigating fundamental mechanisms leading to cardiac remodeling and ventricular growth in other animals, including humans. Hicks' research is supported by the Integrative Organismal Biology program at the National Science Foundation. ...Molecular thermometers on skin cells detect heat and camphor
...ate our sense of touch. Touch is perhaps the most fundamental of our five senses because it works through our largest organ, the skin. Through the skin we can detect temperature, texture, and understand both pleasure and pain. A few years ago, the Scripps Research and GNF team, which was led by Scripps Researc...To Stop Evolution: New Way Of Fighting Antibiotic Resistance Demonstrated By Scripps Scientists
...Like Death and Taxes Anymore This research raises fundamental questions about evolution. Biologists have often thought about evolution in the same way many think about death and taxes -- something inevitable. But Romesberg is a chemist, and he found himself asking not only how, but why evolution happens. For t...At the molecular level, the predator is the prey
...om flowing freely. "These channels are absolutely fundamental to every aspect of nerve and muscle function and are highly specific gateways for sodium ions," said IUB biologist Edmund Brodie III, one of the paper's coauthors. "If the channels change too much or in the wrong way, they can't perform their basic, ...'EuroVacc 02' HIV Vaccine Trial Begins
...oordinating European efforts and raising funds for fundamental and clinical research so as to accelerate the development of a safe and effective vaccine against HIV infection. The Foundation also promotes educational and training programmes relevant to vaccine development worldwide. ### Notes: Contrary to c...DOE JGI launches IMG public online microbial genome data clearinghouse
...the IMG development effort. "This goal follows the fundamental principle that the value of genome analysis depend...ompare fungal and bacterial genomes and scrutinize fundamental processes like speciation and adaptation." In addition to curating the IMG system, DOE JGI will con...