UCSB scientists probe sea floor venting to gain understanding of early life on Earth
...ge flank system on the chemistry of the ocean, are fundamental global-scale processes. On dives in the submersible Alvin, Haymon and her UCSB colleagues –?Ken C. Macdonald, Sara B. Benjamin, and Christopher J. Ehrhardt –?studied "abyssal" underwater hills that cover a large geomorphic terrain on the ocean floor...UAB scientists discover the origin of a mysterious physical force
... and the withdrawal of proteins. Both of these are fundamental in biomedical research, since a substantial part of the process of designing new drugs is based on understanding how substances penetrate cell membranes to enter cells. These drugs are often proteins designed to prevent or strengthen the action of ot...Quantum Dots Research Leads to New Knowledge about Protein Binding in Plants
...onemore step towards a better understanding of the fundamental processesinvolved, namely the network of the signaling process in plantreproduction,?said Ozkan. "A better understanding of the interactionof SCA with pollen tubes could help with successful plant breeding?...Newly-discovered class of genes determines ?and restricts ?stem cell fate
...e a potential reservoir for tissue regeneration. A fundamental understanding of the molecular programs that regulate stem-cell differentiation is necessary for harnessing this potential. ### This work was supported by grants from the National Institutes of Health. Epstein's coauthors are Deborah Lang, Min Min ...Inexpensive, mass-produced genes core of synthetic biology advances at UH
...rove health care,medicine and the environment at a fundamental level.Using current methods, programmed synthesis of a typical gene coststhousands of dollars. Thus, the prospect of creating the most primitiveof living organisms, which requires synthesis of several thousandgenes, would be prohibitive, costing mill...Scientists seek answers on what activates deadly anthrax spores
...x is clear, as spore germination and outgrowth are fundamental to proliferation." Claiborne, co-director of Wake Forest's Center for Structural Biology, added, "Basic understanding of the regulatory signals that promote germination will enable discoveries leading to drugs that block the process." The research ...Found: Missing sequence of the human Y chromosome
...emale controls, confirming thatthis sequence was a fundamental part of the Y chromosome.More surprising, however, was Rappold's finding that this "missing"sequence was not unique to the Y chromosome. Rather, this sequenceexhibited between 95-99% homology to sequences on exactly half (11 of22) of the other chromo...Needling Chromosomes Reveals Cell Division Secret
...uzzle of how one cell divides into two -- aprocess fundamental to all organisms.In the Dec. 14, 2004, issue of Current Biology, Leocadia Paliulis andBruce Nicklas report their progress in understanding how the pairs ofchromosomes in each cell manage to balance their adhesion to oneanother and their release durin...New research questions basic tenet of neuron function
...ite and sexuality. A better understanding of such fundamental mechanisms of neurotransmitter release will aid researchers in their investigations of psychiatric disorders and neurological disorders such as mental retardation, autism, depression and epilepsy, all of which have been linked to abnormal neurotransm......e theoretical biologist and biophysicist also made fundamental contributions to structural studies of important b...man consciousness and free will, can be reduced to fundamental laws of physics and chemistry, and can thus be explained entirely in rational, scientific terms. Af...Nano-Probes Allow an Inside Look at Cell Nuclei
...bes inside cell nuclei where they can track life's fundamental processes, such as DNA repair, for hours on end. "Our work represents the first time a biologist can image long-term phenomena within the nuclei of living cells," says Fanqing Chen of Berkeley Lab's Life Sciences Division, who developed the techniqu...Unexpressed But Indispensable -- The DNA Sequences That Control Development
...re than a fruitfly, fewer than a rice plant—a more fundamental genetic truth has often been obscured. The express... sequences conserved between them are likely to be fundamental to vertebrate development. Through sequence alignment with increasingly strict criteria, they identi...Scientists discover that host cell lipids facilitate bacterial movement
...n cytoskeleton. Our discoveries provide additional fundamental clues as how cells move." These findings may also open the door to using PI3-kinase inhibitors or other agents that lower PIP2 and PIP3 levels to slow the spread of Listeria and control infection in patients who are not responding to antibiotics, al...Measuring the impact of post-genomics on Mediterranean populations
...ance human health? To achieve this, they continue, fundamental and applied research is needed and supported, stressing integrated, multidisciplinary and coordinated effort. The two-day workshop highlighted not only the impact of recent progress in genomics on human health in developing countries, but also ident...New Insights Into HIV Immunity Suggest Alternative Approach to Vaccines
... proteins activate self-reactive antibodies. "The fundamental problem in all of HIV vaccine research has been that when you inject the envelope of the HIV virus into people or animals, no broadly neutralizing antibodies ?those antibodies that kill most HIV strains ?are made. This provides a plausible explanatio...Use of PET can reduce, may eliminate more strenuous drug development trials with animals
...l animals. Small animals, especially mice, play a fundamental in the study of human biology and disease. Mice have nearly the same set of genes as humans, offering an opportunity to learn about the function of the many genes shared by both. This could lead to improved diagnosis of disorders such as Alzheimer's ...Hirsute Or Hairless? Two Proteins May Spell The Difference
...Understanding how hair develops sheds light on the fundamental processes that generate a wide range of tissues an...structures emerge from single sheets of cells is a fundamental question in developmental biology. The dispensability of hair follicles makes them the perfect model...New online portal merges vast data on Gulf of Maine ecosystem
...n the Gulf of Maine to the surrounding environs is fundamental to ecosystem-based management. The Dynamic Atlas creates the opportunity for credible gains in our knowledge about how the patterns of life in the Gulf are unfolding." For example, the Atlas can be used for simple analyses, such as calculating the r...50-year-old Mystery Solved: Protein Tags Regulate Key Ion Channel
... flow in and out and so are key regulators of many fundamental processes in biology. "Ions are the currency of the cellular world," explained Goldstein. "Cells collect some ions, others they discharge. Ions are stored, spent, and exchanged." "Cellular solvency," he added, "the ability to respond to the stimuli...Multi-purpose protein regulates new protein synthesis and immune cell development
...rnal of Clinical Investigation. Kaufman studies fundamental signaling pathways involved in the production of new proteins in the cell's endoplasmic reticulum (ER). The process begins with chains of amino acids, which are deposited in the ER membrane in response to coded instructions from genes. Chaperone prot...