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Tag: "function" at biology news

Reactivated gene shrinks tumors

...r drugs. "If we can find drugs that restore p53 function in human tumors in which this pathway is blocked, they may be effective cancer treatments," said David Kirsch of MIT's Center for Cancer Research and Harvard Medical School, one of the lead co-authors of the paper. The study will be published in t...

Williams College biologist explores photosynthetic apparatus

... will support her work in exploring the structure, function and evolution of the photosynthetic apparatus in one of the most important marine primary producers of the world. Her project is titled "Photosynthetic Response to Abiotic Stress in Prochlorococcus, a Globally Important Marine Cyanobacterium." It ad...

Nanoparticles can track cells deep within living organisms

...group will evaluate how nanoparticle-labeled cells function in living organisms. "We'll track injected cells in real time and see where they accumulate and how long they live," Partlow says. "Then we'll go on to investigate how they work in therapeutic applications." ...

Protein therapy may reduce infarct size in heart attack patients

...803). Researchers performed tests to assess heart function at various time points and assessed safety and cardiac outcomes through six months. This trial was designed as an exploratory study to assess the potential impact of KAI-9803 in this “first-in-human?study. Results indicate that KAI-9803 may be as...

How fish conquered the ocean

...nthic character of the eggs. The alteration in the function (neo-functionalization) of one of the duplicated genes (paralogues) allowed its yolk protein products to be broken down to free amino acids and thus drive hydration of the maturing eggs. The timing of these events matches the appearance of the vast n...

Stem cell therapy shows promise in regenerating damaged muscle in heart attack patients

...significant improvements in heart, lung and global function compared to those who received a placebo, according to six-month Phase I study data presented at the American College of Cardiology's Innovation in Intervention: i2Summit in New Orleans on March 25. Rush was one of 10 premier cardiac centers across ...

A first glimpse of the influenza replication machine

... Molecular Biology, investigates the structure and function of the protein and sheds light on how polymerase m...ction of its proteins. Interfering with polymerase function would prevent the virus replicating, thereby reducing the spread of the virus and the severity of th...

Minuscule molecules pack a powerful punch

...ma development. "Very little is known about the function of the hundreds of microRNA genes," said Dr Antony...larly important gene, c-Maf, which is critical for function of populations of T-cells, is a target for the action of miR-155. The consequences of removal of...

Scientists reveal structure of gateways to gene control

...ut the cell's DNA, control whether or not a gene's function can be turned on in a particular cell. The stud...cular transcription machinery. "We think that the function of the nucleosome is to control the gateway to transcription," Pugh said. The research reveals ho...

Does a peptide affect the heart's response to social isolation?

...ole in regulating both behavior and cardiovascular function in humans. Negative social interactions, such as l... the relations between social behavior and cardiac function in humans. ...

Genes and genius: Researchers confirm association between gene and intelligence

...asing I.Q., and I expect overall intelligence is a function of the accumulation of all of these genetic variants, not to mention environmental influences ranging from socio-economic status to the value that's placed on learning when children are growing up." ...

Scientists identify a candidate gene for osteoporosis

...develop therapies that are based on inhibiting the function of the DARC gene," explains Dr. Subburaman Mohan, Ph.D., a Senior Scientist at the Loma Linda VA Medical Center and a Professor of Medicine and Biochemistry at Loma Linda University. "We will also be able to develop genetic screens to identify indi...

When smell cells fail they call in stem cell reserves

.... “The HBCs act as a fail-safe to ensure continued function of the sense of smell.? The discovery of these two distinct types of stem cells in one neural tissue is a first, says Reed, who is interested to see if other types of nerves in the body have similar repair mechanisms in play. ...

HIV dementia alarmingly high in Africa

...tment can even restore completely normal cognitive function to some of those affected. The study looked at 178 subjects in Kampala, Uganda, from September 2003 to January 2004. Seventy-eight were HIV-positive patients recruited from the Infectious Disease Clinic in Mulago Hospital, Makerere University, an...

New study is first to link romantic relationships to genes

...a link between a set of genes involved with immune function and partner selection in humans. Vertebrate species and humans are inclined to prefer mates who have dissimilar MHC (major histocompatibility complex) genotypes, rather than similar ones. This preference may help avoid inbreeding between partners, a...

NYU scientists identify how development of different species uses same genes with distinct features

...cle. Orthodenticle performs the anterior promoting function of bicoid while anterior localization of giant mRNA represses posterior development. "This comparison of the molecular mechanisms employed by two independently evolved species not only uncovers those features essential to this portion of developme...

Prion disease treatable if caught early

...we conclude that the dramatic benefits to neuronal function and survival in prion-infected mice we have shown here support targeting neuronal [prion protein] directly as a therapeutic approach," wrote Mallucci and colleagues. "Our findings of early reversible neurophysiological and cognitive deficits occur...

It's in your head: The brain's own globin defends you from shock and stroke

...lobin or myoglobin, however, neuroglobin's primary function does not appear to involve transporting oxygen. In...lecule in our head that protects and helps restore function in the brain is an important step toward helping people who experience strokes or similar problems,"...

Mechanical 'artificial hearts' can remove need for heart transplant by returning heart to normal

...ies can shrink the enlarged heart and enable it to function normally once the LVAD is removed. For the stu... in this study could also be used to restore heart function amongst heart patients who are not awaiting transplants. LVADs work by being connected to the l...

How fish mend a broken heart

...n restore cells lost in the course of normal organ function or after minor injury but cannot regenerate after major damage or removal of structures. "It is believed that the capacity for regeneration is an ancestral condition that has occasionally been lost in the course of vertebrate evolution." Poss said....

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