Monoclonal antibody reduces exacerbations in asthmatics
...actory asthma have also shown improvements in lung function and airway hyperresponsiveness." During the study, 13 of the 18 patients on placebo (72 percent) experienced exacerbations, as compared to only four out of 14 patients (29 percent) on infliximab therapy. All patients in the study cohort continued t...Computer with brain connections changing quality of life of paralyzed
...esses and the probability for an external event to function as a link between response and consequence becomes progressively smaller, it may eventually vanish altogether. Researchers have found that by implementing a BCI before the CLIS state occurs, a patient can be taught to communicate through an elect...Gladstone investigators identify a new protective action for the powerful anti-HIV factor, APOBEC3G
...nology (GIVI) have identified a previously unknown function of APOBEC3G (A3G), a protein that acts against HIV...effect of the small form of A3G and the protective function of the large A3G complex against select mobile genetic elements," Greene said. Gladstone scientists...Proteins may predict lung transplant rejection
...at exist in the lung. Disease disturbs protein function Lung transplants are a common therapy for many end-stage lung diseases such as chronic obstructive pulmonary disease, cystic fibrosis, pulmonary hypertension, idiopathic pulmonary fibrosis and other diseases. Patients who receive a new lung ma...New study aims to stop sepsis in its tracks
...restore blood pressure, and monitor cardiovascular function and other organ activity. It was developed several...can serve as molecular markers to help track organ function and recovery progress in patients. This molecular approach may also shed light on new ways to unders...Interaction between lymph and liver cells may affect immune response
... the endothelial barrier, and that hepatocytes can function as APCs. In fact, this T cell activation in the li... They suggest that the hepatocyte microvilli could function as a rapid screen for circulating lymphocytes, which might then decide to adhere and start the TEHLI...Growth factor stimulates rapid extension of key motor neurons in brain
...ers, and their damage contributes to loss of motor function in spinal cord injuries. Since they are embedded among hundreds of other types of neurons in the cerebral cortex, it has been difficult to study CSMN, and little has been known about cellular and molecular factors that control their growth and devel...Neuron cell stickiness may hold key to evolution of the human brain
... many millions of years, the sequence is likely to function as a switch turning genes on or off. In this late...ts that the accelerated evolution of adhesion cell function occurred independently in humans and chimpanzees. We failed to detect any CNS enrichment near cell ...Living view in animals shows how cells decide to make proteins
...rgans. These varied proteins, in turn, dictate the function of each tissue or organ. The findings also may offer insight into a number of diseases, including cancer, in which the genetic process -- called alternative splicing -- goes awry and produces the wrong proteins, the scientists said. The scienti...With fruit fly sex, researchers find mind-body connection
... the gene are removed ?a powerful way to test gene function ?flies have the physical features of both sexes. As a result, these mutant females are not recognized by normal males and these mutant males are not recognized by normal females ?and none of the mutants can mate. So this makes it difficult for scient...Stem cells engage in dialogue with the cells that regulate their futures
...onstrating that stem cells can contribute to niche function has far-reaching consequences for stem-cell therapies and may provide insight on how cancer might spread throughout the body via populations of cancer stem cells." Ruohola-Baker added that stem cells hold high hope in regenerative medicine: tappin...Power emerges from consensus in monkey social networks
...This requirement is reflected in the structure and function of communication networks. A goal of this research has been to study communication at a group level rather than the more traditional communication we associate with pairs." Using information theory, the researchers show that power emerges through co...'Killer' B cells provide new link in the evolution of immunity
...rtant for not only understanding the evolution and function of immune cells in fish but also may point to novel roles of B cells in mammals. Their findings also have an agricultural implication. Vaccines currently given to farmed salmon, for example, appeal to the fish's adaptive immune response, which this r...Harvard scientists identify compounds that stimulate stem cell growth in the brain
...h in the brain, which may one day lead to restored function for people affected by Parkinson's disease, strokes, multiple sclerosis, and a wide range of neurological disorders. These findings, which appear in the September 2006 issue of The FASEB Journal, provide important clues as to which compounds may be r...New gene linked to bipolar disorder
...researchers do not yet know what the gene's normal function is or how these mutations might be contributing to the disorder. Professor Hugh Gurling, UCL Department of Mental Health Sciences, says: "The next step is to determine the role of the Slynar gene in the brain and how abnormalities in this gene may...Tearing down the fungal cell wall
...proaches to look in detail at the link between the function of the gene and its impact on the structure of the...tes in fungal biology. For years long ignored, the function of natural products is rapidly becoming one of the hot topics in fungal biology; the findings report...Researchers seek to design first treatment for neuroAIDS
...urn to work, a condition that often reduces mental function by about 25 percent, and for which there is no approved treatment, deserves attention." A Better Understanding Researchers believe that the virus itself secretes toxins that signal too many human nerve cells to begin programmed cell death (apopto......inciples differ in bones with different mechanical function and how they may be affected by age and disease....The function of horned beetles' wild protrusions has been a mat...ity Bloomington scientists present an entirely new function for the horns: during their development, Onthophagus horned beetles use their young horns as a sort ......urg, Phillips, and their colleagues identified the function of a C. elegans protein called HIM-8. This protein binds to and helps bring together copies of the worm's sex chromosome (the X chromosome) to achieve stable pairing, called synapsis. Now Dernburg and Phillips have found three new genes, which they h...