Dissecting the machinery of nicotine's reward
...r subunits] may be a necessary requirement for the full expression of the sequence of events leading to nicotine reinforcement." The researchers said that the findings "are consistent with the suggestion of a hierarchical role of the two subunits." While the ß2 subunit would mediate a "global tonic" regu...Diabetes hits 275 Australians each day as pandemic spreads
...ing proof that Australia's diabetes epidemic is in full flight." Professor Zimmet said. In addition to measuring the development of new cases, the follow-up study showed that during the last 5 years: People's waistlines increased on average by 2.1 cm and their weight by 1.4 kg People with prediabetes*...New bird flu drug promises to beat the problem of resistance
...e flu drug has become all the more pressing as the full extent of resistance ?the ability of the influenza virus to withstand drug treatments - becomes more widely understood. Both Tamiflu and Relenza, the two drugs currently being stockpiled by governments in preparation for a global outbreak of bird f...Pitt phage hunter takes on tuberculosis
...six to nine months. Many people don't complete the full course of treatment, which leads to increasing antibiotic resistance against the disease. More effective treatments could be on the way, however, with a new five-year, $2.8 million grant from the National Institutes of Health to Graham Hatfull, Ebe...Massive duplication of genes may solve Darwin's 'abominable mystery' about flowering plants
... single-gene duplications, simultaneously having a full genome's worth of raw material to elaborate new genetic function could drive sudden evolution. But because of the rapid, massive gene loss after a whole-genome duplication, these events are notoriously difficult to detect after millions of years. S...Reversing 'hibernating' heart muscle focus of UB researchers
... of manipulating these pathways will be to restore full contractile function." Areas of hibernating myocardium are common in patients with heart failure arising from coronary artery disease, Canty noted. "Determining how this impacts prognosis is the focus of the UB Cardiovascular Center's PAREPET (Pred...MUHC announces a transplant first in Quebec
...ient has now fully recovered and is again living a full and rich life. "I am extremely impressed with the doctors at the MUHC; from the onset I had unquestioned confidence in their ability to perform this complex surgery," says Patrice Dionne. "I'm so thankful that I will now be able to enjoy this fathers...Green tea and the 'Asian Paradox'
...ool of Medicine researcher. "We do not yet have a full explanation for the 'Asian paradox,' which refers to the very low incidence of both heart disease and cancer in Asia, even though consumption of cigarettes is greater than in most other countries," said Bauer Sumpio, M.D., professor and Chief of Vasc...Cutting calories slightly can reduce aging damage
.... The old sedentary rats that ate until they were full had increased levels of harmful oxidizing and inflammatory molecules in the liver that were associated with cell damage caused by aging. Meanwhile, aging rats that exercised and consumed a calorie-restricted diet, had the reverse outcome - they showe...US infant mortality rate fails to improve
...o?even before pregnancy ?to help give babies their full nine months of gestation. Women should avoid the dangers to the fetus of smoking, as maternal smoking is associated with higher infant mortality rates and increased risk of preterm and low birthweight births. The March of Dimes also urges women to t...Patients to benefit from novel technology revolutionizing high-speed molecular imaging
...ion imposes very long acquisition times of up to a full hour and sometimes more," he added. "This new camera technology enables acquisition times that are shorter by an order of magnitude (2 minutes vs. today's 20 minutes for a cardiac scan), better image quality (up to two times the image resolution) and...'Smart' genetic therapy helps the body to heal itself
...s, which will lead in turn to a safe and efficient full body treatment for DMD patients. Currently no therapy is available for this disease, which represents a huge psychosocial and economic burden to patients, carers and society." ...Genetic 'roadmap' charts links between drugs and human disease
...mmon language of "genomic signatures," meaning the full complement of genes that the drugs turn on and off. To create a first-generation Connectivity Map, the scientists measured the genomic signatures of more than 160 drugs and other biologically active compounds. They next developed a computer progra...Scientists' cell discovery unearths evolutionary clues
The full family tree of the species known as social amoebas has been plotted for the first time ?a breakthrough which will provide important clues to the evolution of life on earth. Researchers, headed by evolutionary biologist Professor Sandie Baldauf, of t...Embryo tests give parents the choice
...nsure that all children are born with achance of a full and flourishing life, says Eric Cohen, head of the bioethics programme at the Ethics and Public Policy Center in Washington DC. "PGD clinics are performing sex selection just to satisfy parental preferences, and embryo screening is being used for lat...Vaccine combined with short-term postexposure antibiotics protects monkeys from inhalational anthrax
...here more than half of the people did not take the full 60-day course--there were no additional anthrax cases," Friedlander commented. "This suggests that the doses of inhaled spores were probably very low. In contrast, computer modeling suggests that protection against higher doses of anthrax spores cou...What animals can tell us about hemorrhage, organ transplants and aging
...index.htm and click on "Week at a glance" for the full Comparative Physiology program. Check out "Conference-Related Press Releases," for more program summaries. Members of the media who want to obtain a complete set of conference abstracts can contact Christine Guilfoy, cguilfoy@the-aps.org or at (301) ...Cell death following blood 'reflow' injury tracked to natural toxin
...injuries, the researchers pumped mouse nerve cells full of PAR-polymer. The cells died, but to be sure PAR-polymer (and not something else) killed them, they examined the brains of mice engineered to lack an enzyme that chews up and gets rid of PAR. These mouse brains contained twice as much PAR-polymer a...Paying attention sets off symphony of cell synchronization
You know the sensation. When something has your full attention you see it vividly. And when you don't pay attention, you're liable to miss something important. Now a new Northwestern University study sheds light on how attention operates. The mystery of how attention improves the perception of incomin...Restoring tamoxifen sensitivity in resistant breast cancer cells
... become less effective over time, might retain its full strength indefinitely if used along with a second drug, according to new research in mice conducted by investigators from the National Cancer Institute (NCI), part of the National Institutes of Health, and their partners. The results appear in the De...