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A gene's first 'kiss' sets off that affair known as puberty

...: What causes puberty to begin? How is it that the full repertoire of reproductive hormones can exist at b... about four to six months of age, then reemerge in full force some 10 to 12 years later? "Puberty is critical to human development. And while there is a fa...

DNA Molecules Used To Assemble Nanoparticles

...ith the DNA strands. "So it's like having a shelf full of Tinker Toys," Baker said. An array of single-functional dendrimers, such as targets, drugs, and contrast agents, and the ability to link them together quickly and easily in many different ways would enable a clinic to offer 25 different "flavors"...

Poor prenatal nutrition permanently damages function of insulin-producing cells in the pancreas

... delivery, all babies nursed and all mothers ate a full diet. "By the time the babies were weaned, at three weeks, the low-birth-weight group had caught up with the others, something we see in human babies too," said Dr. Patti. "They looked and acted the same. There was nothing outwardly different about t...

Whole genome fine map of rice completed

...enome shortgun approach. Through searches of 19079 full length cDNA, 97.7% of complete genes were found in the two genomes. After adjusting for residual errors of predictions with EST data, the number of genes is estimated to be between 30,000 to 40,000. Among them, only 2-3% genes are unique to any one o...

Finding Cures For Tropical Diseases: Is Open Source An Answer?

... a summary from ScienceDaily is available in the full post. Onlyabout 1% of newly developed drugs are for tropical diseases, such asAfrican sleeping sickness and dengue fever. While patent incentiveshave driven commercial pharmaceutical companies to make Western healthcare the envy of the world, the c...

Novel Enzyme Shows Potential As An Anti-HIV Target

...pression. Without Tat, HIV transcripts don’t reach full length and can’t effect viral replication. In a new study, Melanie Ott and colleagues identify an enzyme that regulates viral transcription by modifying Tat. The regulation of HIV genes depends on a complex interplay between proviral DNA, cellular p...

Researchers reveal the infectious impact of salmon farms on wild salmon

...on habits. "There's a double bottom line here. The full ecological costs of industrial scale salmon farming must be quantified as well as the economic ones," says Volpe. "For the migratory runs we studied, there may be very little time left." ...

Clam embryo study shows pollutant mixture adversely affects nerve cell development

...reated embryos to check the visual data. Read the full paper ...

Study identifies predictors of HIV drug resistance in patients beginning triple therapy

...reated embryos to check the visual data. Read the full paper ...

Papers of DNA Pioneer and Nobel Laureate Francis Crick Added to National Library of Medicine’s Profiles in Science Web Site

...letters at a time, evidence that made possible the full elucidation of the code by 1966. Crick then turned to developmental biology, the study of how genes control the growth and specialization of organs. In 1976, Crick moved to the Salk Institute for Biological Studies in La Jolla, California, where he ...

First real-time view of developing neurons reveals surprises, say Stanford researchers

...esh of the brain. Because the group could see the full branching structure of a neuron each time it fired, they could watch the branches grow and recede like a tree waving in the wind, losing the occasional twig. Over time, the network of branches stabilized into the mature form. "We're looking at a dyn...

Scientists identify new model Of NK cell development

...he provocative observation that lymph nodes, while full of CD56 bright cells, are significantly lacking in their counterparts, the CD56 dim cells. "Our next goal is to determine if there is some developmental continuum at work here, supporting the notion that CD56 bright cells are really just immature CD...

World's largest rainforest drying experiment completes first phase

...tower 130 to 150 feet above the ground, basking in full sunlight, begin to falter and die. The death of large trees ?trees that may take centuries to reach the top of the forest canopy and have trunks greater than 10 inches in diameter -- increased from about one percent per year before the rainfall exclu...

Kinovate Life Sciences Launches Nittophase?High Performance Solid Support For Oligonucleatide Synthesis

...unit cost, as well as potentially higher yield and full length purity, reducing cost-of-goods. NittoPhase?will be commercially available in two grades; NittoPhaseTOS?for high loading applications, and NittoPhaseROS?for lower loading applications. In this way, NittoPhase?offers a solution for the entire sp...

Nonlinear Dynamics announces more details of its global partnership with PerkinElmer

...last week, PerkinElmer will distribute Nonlinear's full range of 1D, 2D and array software. However the agreement also represents the formation of an integrated partnership between the two companies, with Nonlinear now formally established as PerkinElmer's principal software partner for all proteomics app...

US life expectancy about to decline, researchers say

...ions will be wrong. And that's what we hope." The full text of the article is available free on the journal's web site at http://www.nejm.org. Olshansky will also present the results of the paper at the Second International Conference on Healthy Ageing and Longevity in Brisbane, Australia on March 20. ...

Potential treatments for neurofibromatosis

...ors develop. "It's like an engine being driven at full speed," said Dr. Clapp. To encourage development of the blood vessels they need, the tumors emit chemical signals that cause the mast cells to congregate in tissues surrounding the tumors. The mast cells create chemicals called growth factors that e...

Variation in women's X chromosomes may explain differences among individuals, between sexes

... The new work extends that earlier finding to the full set of X-linked genes and also further reveals that individual women exhibit extensive differences among them with respect to X inactivation, Willard said. In their study, the researchers isolated cell lines from each of 40 women. They then measured...

UCLA launches $20 million stem cell institute to investigate HIV, cancer and neurological disorders

...edicine. "As dean, I am committed to advancing the full potential of stem cell research to find novel and more effective therapies to treat many diseases for which present-day therapy is either unsatisfactory or unavailable." Because the university and medical school at UCLA are located on the same campu...

Gene Signatures Predict Interferon Response For Multiple Sclerosis Patients

... (marked by acute flare-ups followed by partial or full recovery), and their RNA was isolated from a class of immune cells called peripheral blood mononuclear cells. After patients started interferon therapy, blood was taken at specific time points over the course of two years. Baranzini et al. measured t...

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