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Tag: "frontline" at biology news

Cracking open the black box of autoimmune disease

... group of white blood cells called T cells are the frontline soldiers of immune defense, engaging invading path.... Failure of the regulatory T cells to control the frontline fighters leads to autoimmune disease. Scientists previously discovered that regulatory T cells a...

Mechanism for Epstein-Barr virus protein's role in blood cancers discovered

...tage of patients are non-responsive to the current frontline drug for treating B cell lymphoma, a CD20 monoclonal antibody." The researchers surmise that the first use of future therapies from these studies could be in lymphoproliferative disease in transplant and immunocompromised patients. ...

Genetic variation alters response to common anti-clotting drug

...ability truly improves patient treatment with this frontline anticoagulant drug." ...

Disabling gene defuses rheumatoid arthritis in mice

...pidly to invaders and normally comprise the body's frontline defenses against bacterial infection. Peng became interested in Foxo3a because of prior studies his research team had conducted on a related gene, Foxj1. Both genes belong to the forkhead family of genes, which regulates the activity of other genes ...

Potential Cure for Lymphoma in HIV patients

...ected patients had undergone previousstandard-dose frontline chemotherapy for their lymphoma, but themajority either failed to achieve a complete remission or had relapsedafter an initial remission. The median length of study follow-up wasapproximately two and a half years, with a range of about six months tos...

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