A link is found between morphine addiction and the tendency to explore
...mes over the period of a few days, the rat is left free and we observe which of the two compartments it prefers. The more the animal likes morphine, the more time it will spend in the compartment that it associated with the effects of this drug, and this gives us an indication of the rat's addiction to th...Flesh-eating bacteria escape body's safety net
...ng "Strep" bacteria use a specific enzyme to break free of the body's immune system, a finding which could potentially lead to new treatments for serious infections in human patients. The research, reported in the February 21, 2006 issue of the journal Current Biology, focuses on the major human pathogen...Antioxidant selenium offers no heart-disease protection
...nts in the study, conducted from 1983-96, who were free of cardiovascular disease when they were recruited. Participants came from seven dermatology clinics in low selenium areas of the eastern United States: Augusta and Macon, Ga.; Columbia, S.C.; Miami, Fla.; Wilson and Greenville, N. C.; and Newington...World faces challenge as life expectancies lengthen, scientist says
...ging technologies are distributed in the unchecked free market, "it's entirely likely to me that we'll wind up with permanent global underclasses, countries that will get locked into today's mortality conditions," Tuljapurkar said. As the gap widens and rich countries continue to invest in anti-aging tech...DNA conclusive yet still controversial, Carnegie Mellon professor says
...an be subjected to DNA testing. But DNA's value to free the wrongfully convicted can be attained only if political leaders allow its full application," Roeder said. "Thousands currently await the evaluation of their cases." In the early phases, technical disputes among scientists impeded the use of DNA e...Powerful technique for multiplying adult stem cells may aid therapies
Adult stem cells may be free of the ethical concerns that hamper embryonic stem cell research, but they still pose formidable scientific challenges. Chief among these is the doggedness with which adult stem cells differentiate into mature tissue the moment they're isolated from ...UW-Madison engineers squeeze secrets from proteins
... "Most research in this area looked at proteins in free solution when in fact, most proteins are confined in some way," says Juan de Pablo, a chemical and biological engineer at the University of Wisconsin-Madison. "What we demonstrate for the first time is that the stability of proteins under severe conf...Study in Science holds promise for a new approach to drug therapy
...e ligand that activates a GPCR on the outside. The free G protein gamma-beta subunit can, for example, "tu...ght about by morphine. In white blood cells, the free G protein gamma-beta subunit activates enzymes that allow the cells to home in on the site of infect...New compound protects against liver cancer
...lamed, they can produce reactive molecules, called free radicals, that can damage DNA and promote cancer development," explained Kensler. "CDDO-Im can also inhibit cancer formation by interfering with this inflammatory process." Because it can stimulate the body's defense mechanisms at such low doses, Ke...New possibilities to fight pests with biological means
...he olfactometer. When the predatory wasps were set free in the central cylinder of the olfactometer, they flew towards the scent-producing plants. The experiments led to an additional, surprising result: in order to react this way, the wasps needed a first exposure to both the corn scent and the caterpill...Oh, rats! Designer animals reveal possible heart disease genes
...esulting from the study, dubbed TREX, is available free of charge at: http://pga.tigr.org/ . TIGR continues to study the panels of designer rat strains, and Lee hopes in the future to knock out specific candidate heart disease genes, directly testing their effects. "With all this information in hand, sc...Removing DNA repair gene causes metabolic syndrome
...ay of enzymes involved in repairing DNA damaged by free radicals that trigger oxidative stress on cell molecules. As a consequence of these studies, the Lloyd laboratory found human homologs to the bacterial repair enzyme and immediately began constructing the repair-deficient mice. "If you have oxidativ...St. Jude projects 90 percent cure rate for ALL
... "This reflects the ability of St. Jude to provide free treatment to all children regardless of their ethnic or racial backgrounds or their ability to pay; and to tailor the treatment according to their specific needs," Pui said. "The significant leadership role St. Jude played is due entirely to the enor...Morning grogginess more debilitating than sleep deprivation, according to CU-Boulder study
...o medical, psychiatric or sleep disorders and were free of medication including alcohol, nicotine, recreational drugs and caffeine. The subjects also spent several hours each day during their six-day, in-patient stay practicing the math test used to quantify sleep inertia. "These were very healthy peop...Some like it hot: Worms at deep-sea vents favor a fiery 45-55°C
...r special aquarium, leaving the deep-sea creatures free to choose any temperature between 20 and 61 degrees Celsius (58 and 142 degrees Fahrenheit). When this thermal gradient was established, all the worms migrated to parts of the tank registering 45 to 55 degrees Celsius. For seven hours the worms chos...Leave it to salmon to leave no stone unturned
... lay her eggs in a nice, gravel-bottom bowl that's free of fine sediments that can smother them. But consider the efforts of the grand dames of the salmon world, the female chinook ?or king ?salmon. The largest females are more than a yard long and tip the scales at 45 pounds or more. The biggest nests a...Nearly half of people who need cholesterol treatment don't get it
...l disorders were common in this population that is free of known cardiovascular disease," said Goff. "And we found that cholesterol treatment and control is far from optimal. The high-risk group had the lowest level of control and there was evidence of gender and ethnic disparities in both treatment and c...For the first time: Longevity modulated without disrupting life-sustaining function
...ding parasites. Highly reactive molecules known as free radicals also unleash DAF-16. If the worms are having a good day in a favorable environment, but for some reason DAF-2 signaling gets turned off precociously, the worms reap the benefit of increased stress resistance and double their lifespan from ...Mayo Clinic researchers challenge sepsis theory
...nces is liberated from "natural suppression." Once free to function, the receptor can trigger the catastrophic cascade of events that is sepsis. The sepsis syndrome can occur during a bacterial infection, as the accepted medical principle holds, or -- as the Mayo Clinic team theory suggests -- it also can......h said. The very tip of the chromosome must remain free to allow access to the site on the enzyme that directly extends the telomeres, Cech pointed out, so the anchor site secures the DNA molecule nearby, slightly closer to its center. Cech is optimistic that the new portrait of the TEN domain will spee...