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Tag: "fragments" at biology news

Exploring the dark matter of the genome

... grind up whole flies and produce libraries of DNA fragments of two sizes, some that are 2 kilobases long" -- a...se fragments. With euchromatin, large, single-copy fragments practically assemble themselves, but it's harder to know how shorter pieces with many repeating sequ...

Ancient retrovirus sheds light on modern pandemic

... of years, and so humans share many retroviral DNA fragments with their primate cousins. Such vestiges of primitive infection, rendered inactive by eons of genetic mutation, make up about 8 percent of the human genome. Innate protection against PtERV1 in humans could be credited, the researchers believe, to ...

An ancient bathtub ring of mammoth fossils

... and approaching as fast as 60 miles an hour. Some fragments may have come from full skeletons churned up and redistributed by later floods, while others may actually have ice-rafted in with erratics....

Scientists identify prion's infectious secret

...enic fungi. When the prion was placed with peptide fragments from baker’s yeast, the baker’s yeast recognition element was activated, and likewise for the pathogenic fungi. Even more striking, Tessier could activate different recognition elements by manipulating environmental conditions, such as temperatur...

DOE JGI sets 'gold standard' for metagenomic data analysis

...data to enable accurate classification of sequence fragments into their corresponding species populations. The...al genomes is first sheared into millions of small fragments to enable the amplification, labeling, and ultimately sequencing. Genome assembly is the process of...

DNA-damage test could aid drug development

...ng an easily detected "micronucleus" consisting of fragments of nuclear DNA. Unlike the current procedure, which injects the compound into a live mouse, the new assay is a cell-culture system that could allow hundreds or thousands of tests to be performed from the bone marrow of a single mouse, and potentially...

Implanting dopamine generators in brain cells obtains improvement in Parkinson's in monkeys

...od of time. The procedure involved implanting cell fragments extracted from the carotid body in the striate are...y injected into the striate area of the brain with fragments from the carotid body of the same animal This region of the brain where the fragments from the carot...

Protein fragments sequenced in 68 million-year-old Tyrannosaurus rex

...instructor in pathology, who sequenced the protein fragments over the course of a year and a half using highly ...eagues isolated and sequenced more than 70 protein fragments from a 160,000- to 600,000-year-old mastodon, providing further evidence of the staying power of an...

Rotavirus can spread beyond the intestine

...arrhea in children, and who have antigens (protein fragments from the surface of the virus) in their blood, also have infectious virus in their blood. Margaret Conner and colleagues from Baylor College of Medicine, Houston Texas, tested samples obtained from hospitalized children with gastroenteritis and compa...

Large size crucial for Amazon forest reserves

...meters every year, leaving a trail of small forest fragments isolated by cleared land. Many species that occur ...ation. "It is no surprise that small isolated fragments lack many species" said Ferraz. "Many birds are so uncommon that they will rarely occur in small plo...

Genes and biomarkers that allow doctors to choose the right therapy for the right patient

...ain tumors to determine which peptides ?or protein fragments ?were active in the tissue environment surrounding... the bacteriophage viruses used to capture protein fragments ?was then isolated and tested. With the library, Dr. Diaz and his colleagues could select peptide...

Scientists find new genetic clue to cause of Alzheimer's disease

...in, or APP, is processed into amyloid beta protein fragments that make up plaques in the brain. The researchers... resulting in increased production of amyloid beta fragments while high levels decreased production. However, the researchers note, other genetic and non-genetic...

40,000-year-old skull shows both modern human and Neandertal traits

...dern humans dispersed into Europe. The different fragments of the reconstructed cranium ?named Oase 2 ?were found in a Late Pleistocene bone bed principally containing the remains of cave bears. They were recovered during a systematic excavation project directed by Professor Trinkaus and Professor Zilhao be...

Mystery of fossilized trees is solved

...e genus Wattieza, a tree fern-like plant. Small fragments of Wattieza have been found in the past, but there was no direct evidence of how large the plant could grow. The new specimens show that they reached at least 8 metres in height and formed the first known forests on earth. Dr Berry, of Cardiff's S...

Discovery of an HIV inhibitor in human blood points to new drug class

...ation of Cell Press. The research team found that fragments of a relatively abundant blood molecule, which they call VIRUS-INHIBITORY PEPTIDE, or VIRIP, acts as a broad-based inhibitor of HIV-1. Moreover, they showed that a few amino acid changes in the fragment enhanced its antiretroviral potency by two orde...

Batten down the hatches against HIV

...mising approach to gene therapy involves short DNA fragments (interfering RNA) that bind to specific genes and ...his has allowed them to successfully introduce RNA fragments that "switch off" the genes for special HIV-specific receptors and co-receptors on the cells?surface...

Speeding 'fingertip' discovery -- 20 years of protein info in 1 place

...agments, separates them by size and identifies the fragments based on their mass - their size and weight. The process improves on previous techniques by breaking up proteins more gently and keeping chemical modifications like phosphorylation intact. Previous spectrometry methods were “just too rough?on the del...

Recently discovered species gain protection

...er extraction clearing the last subtropical forest fragments surrounding it. Now, support from the American Bird Conservancy (ABC) and partners has allowed for the purchase of further habitat area in a crucial move to protect the chestnut-capped piha and other Endangered species. "Thanks to the generous su...

'Terror bird' arrived in North America before land bridge, study finds

...toe bone in Texas, and in Florida by about 40 bone fragments from different skeletal regions. MacFadden's team also analyzed six specimens from the Santa Fe River in north Central Florida. "We found that the Titanis fossils were 2 million years old and not 10,000 years old as had been suggested," MacFadden s...

New science of metagenomics 'will transform modern microbiology'

...ed genetic material consists of millions of random fragments of DNA that can be cloned into a form capable of being maintained in laboratory bacteria. These bacteria are used to create a "library" that includes the genomes of all the microbes found in a habitat, the natural environment of the organisms. Alth...

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