New imaging technique tracks traffic patterns of white blood cells
...re able to view white blood cell subsets and their forming microdomains in the vascular system in real time. In the upcoming March issue of Nature Methods, the new research displays the migration and inner workings of white blood cells in the small veins and bone marrow of mice. "Intravital micropscopy (IV...Nanoparticles can track cells deep within living organisms
...n to migrate to and incorporate into blood vessels forming around tumors in mice. The researchers believe the cells could soon be used in clinical settings. "Kathy and colleagues showed that we can scan for these cells at the same MRI field strength we are using in medical imaging," Wickline says. "Altho...Gallium: A new antibacterial agent?
... cystic fibrosis. Ga also prevented P. aeruginonsa forming biofilms, the multi-cellular bacterial communities responsible for chronic bacterial infections, and killed both free-living bacteria and bacteria in biofilms. Furthermore, inhalation of Ga protected mice from both acute and chronic P. aeruginonsa lu...RNA enzyme structure offers a glimpse into the origins of life
...nother stem are positioned over the ligation site, forming a pocket where the reaction takes place. A magnesium ion bound to one stem and positioned in the pocket plays an important role in the reaction, Robertson said. The structure indicates that this artificially selected ribozyme uses reaction mechani...Scripps research study reveals structural dynamics of single prion molecules
...uctuates among several different structures before forming intermediate shapes during the amyloid assembly process. The intermediate stages of the process are critically important, Deniz noted: "No single native unfolded protein is capable of initiating the amyloid cascade because of this constant shape-...Cold sore virus might play role in Alzheimer's disease
...to infect a cell. Nectin-1 plays a crucial role in forming synapses, the structures between brain cells that move information and signals from one cell to the next. The team is studying whether herpes somehow disturbs the receptor, possibly altering the structure and function of the synapse. Damage to synaps...McBride shows DNA detective work with paper-eating bacteria that 'glide'
...ce of the cell, and he thinks some are involved in forming nearly invisible filaments around the perimeter of the cell. These filaments were recently imaged in collaboration with Sriram Subramaniam and Jun Liu at the National Institutes of Health by cryo-electron tomography. "The filaments may be the cel...Imaging pinpoints brain regions that 'see the future'
...ring, but not much is known about how we go about forming these mental images of the future," says Karl Szpunar, lead author of the study and a psychology doctoral student in Arts & Sciences at Washington University. "Our findings provide compelling support for the idea that memory and future thought ...Latent memory of cells comes to life
...al genetic information adopt very different fates, forming tissues that have apparently very little in common with each other, such as skin, brain, or bones. Mechanisms at the origin of this so-called cellular differentiation are those for which researchers at the University of Copenhagen have a possible cla...Scientists develope a new model of artificial canine skin
... conditions exposed to air. The cells proliferated forming the various layers of the epidermis. The model ... of expression as that of normal canine skin, even forming a basal membrane, which also maintains the characteristics of conventional skin....UQ research heralds vaccine technology breakthrough
... because, along with helping children, it included forming a new type of vaccine. The research group has developed a "recombinant" vaccine using the existing Hepatitis B vaccine to carry the RSV peptides. "Hepatitis B surface antigen forms virus-like particles, which are the vaccine used for Hepatitis B va...Cancer patients monitor fatigue in real time
...preading to the bone marrow, causing anemia and by forming toxic substances in the body that interfere with normal cell functions. "People who are having problems breathing -- another symptom of some cancers -- may also experience fatigue." According to Hacker, this is the first study of real-time coll...Protein enables discovery of quantum effect in photosynthesis
...cillations meeting and interfering constructively, forming wavelike motions of energy (superposition states) that can explore all potential energy pathways simultaneously and reversibly, meaning they can retreat from wrong pathways with no penalty. This finding contradicts the classical description of the ph...Genome of Clostridium botulinum reveals the background to world's deadliest toxin
...is its ability to hibernate when times are hard by forming dormant spores. More than 110 of its set of almost 3700 genes are used to control spore formation and germination when opportunity arises. "C. botulinum shows us one extreme of the ways that bacteria can make the most of animal hosts," explai...St. Jude study shows genes play an unexpected role in their own activation
...nt genes in the brain that are key to learning and forming memories.” A long-term implication of this work is that one day it might be possible to manipulate CREB’s co-factors to treat disease. “A drug that blocked the specific co-factors CREB needs in the liver to trigger activity of genes that make gluc...Bacteria ferry nanoparticles into cells for early diagnosis, treatment
...ient cell they are engulfed by its outer membrane, forming "vesicles," or tiny spheres that are drawn into the cell's interior. Once inside the cell, the bacteria dissolve the vesicle membrane and release the cargo. The method might be used to take images of diseased tissues by inserting a cargo of fluore...Physicist cracks women's random but always lucky choice of X chromosome
...e gene can be itself blocked by a plug of proteins forming on top of its specific location on the chromosome but they had little idea as to why this should happen randomly to one X chromosome’s gene and not the other. Scientists are extremely uncomfortable with this randomness and have sought a clear scie...