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A gene's first 'kiss' sets off that affair known as puberty

... that awkward phase when boys and girls are primed for their sexual reproductive years as men and women, ...ty's deep-seated neurobiological mechanisms could, for instance, help prevent precocious or delayed puberty from occurring in some children," noted the stu...

Chemists create 'Superbowl' molecule; May lead to better health

...a development that could one day score a touchdown for better health, chemists in Australia have created a "superbowl" molecule that shows promise for precision drug delivery, according to a recent study in the Journal of the American Chemical Society...

DNA Molecules Used To Assemble Nanoparticles

...essor of Nanotechnology and director of the Center for Biologic Nanotechnology at U-M. Nanoparticle comp...is process is long and difficult, requiring months for each new molecule added to the dendrimer in sequential steps. And the yield of useful particles drop...

Bioartificial kidney under study at MCG

...the University of Michigan, can help turn the tide for some patients by more closely mimicking the many i...ons of the kidney. In ICUs today, doctors may opt for newer continuous dialysis therapies in which patients with renal failure receive dialysis around the...

Viral DNA sequence a possible trigger for breast cancer

...e an important and previously unrecognized trigger for breast cancer. The DNA sequence in question is us...dy puts the spotlight on a potential new mechanism for virus-induced breast cell transformation, which has largely been attributed to the integration of vi...

Wisconsin scientists grow critical nerve cells

...important because they provide critical guideposts for scientists trying to repair damaged or diseased ne...p victims of spinal-cord injuries, or pave the way for novel treatments of degenerative diseases such as amyotrophic lateral sclerosis (ALS), also known as...

New push for public health, AIDS spending at African Union summit

... there will be not just talk about an HIV strategy for the AU but how to tackle an action-oriented plan,"...heir disease, which has no known cure. But demand for free drugs vastly outstrips their supply, the cost of the drugs - at some $US600 annually for the re...

Association of herpesvirus with lung disorder questioned

...imens from a small number of subjects. They looked for evidence of HHV-8 in samples of lung tissue from 1...to question, there are other possible explanations for the divergent data. For example, the pathogenesis of primary pulmonary hypertension in Japan may be ...

Man and mouse share genome structures

...Eric Lander, and their Broad Institute colleagues, for the daunting computational analysis required to in...n structures could be activating sets of HOX genes for specific developmental programs. This global activation may have implications for understanding mec...

Adding Radiation Therapy To Chemotherapy Improves Survival In Patients With High-risk Breast Cancer

...effects, including cardiac deaths, were acceptable for both groups of patients. "Our results, and those from other groups, confirm that in situations where residual disease remains, adjuvant chemotherapy alone in high-risk breast cancer patients is suboptimal and that the addition of locoregional radiat...

Novel Asthma Study Shows Multiple Genetic Input Required; Single-gene Solution Shot Down

...effects, including cardiac deaths, were acceptable for both groups of patients. "Our results, and those from other groups, confirm that in situations where residual disease remains, adjuvant chemotherapy alone in high-risk breast cancer patients is suboptimal and that the addition of locoregional radiat...

Jump-starting T Cells In Skin Cancer

... authors found significantly more T cells specific for non-vaccine tumor proteins than were detected before vaccination. Vaccine-specific T cells, on the other hand, became detectable but did not expand to large numbers. Thus, reinvigoration of existing tumor-specific T cells after vaccination did not re...

Molecular biology fills gaps in knowledge of bat evolution

... coauthors the paper, titled A Molecular Phylogeny for Bats Illuminates Biogeography and the Fossil Recor... and Paul Bates of the Harrison Institute's Centre for Systematics and Biodiversity Research, Kent, U.K. "The present work advances our understanding of w...

Scientists ID molecular 'switch' in liver that triggers harmful effects of saturated and trans fats

... a molecular mechanism in the liver that explains, for the first time, how consuming foods rich in satura...vidence pointed to the liver, which is responsible for the body's synthesis of triglycerides and cholesterol, but the molecular chain of events from eating...

A new mechanism of regulating RNA degradation

...ted video game player knows, the first requirement for using a weapon or tool is finding it. And it is no different for cell biologists and clinicians who want to take control of gene expression in cells to create therap...

FDA Approves Human Hookworm Vaccine for Phase I Safety Trials

...ted video game player knows, the first requirement for using a weapon or tool is finding it. And it is no different for cell biologists and clinicians who want to take control of gene expression in cells to create therap...

Deficient DNA Repair Capacity Associated With Increased Risk Of Breast Cancer

... have suggested that deficiency in cells' capacity for DNA repair contributes to the accumulation of DNA ...igning studies of DNA repair capacity and the need for the development of better laboratory tests for such studies. "When DNA repair capacity can be measur...

Spleen may be source of versatile stem cells

...imitive stem cells in thespleen that are important for healing several types of damage orinjury," says De...cocca is alsospearheading an effort to raise money for a clinical trial of theislet-regeneration technique in human patients. For more informationabout thi...

Genes In The Interferon System Important In Systemic Lupus Erythematosus

... SLE, combined with world leaders in thetechnology for large-scale genetic analyses and statistics. The g...ciated with the diseaseSLE. One of the genes codes for a so-called thyrosinkinase enzyme,whose function is to convey signals from interferon outside the ce...

UCSB scientists probe sea floor venting to gain understanding of early life on Earth

...century, and have now become a powerful motivation for research and exploration, according to the Nationa...esent both the cradle of life on Earth and a model for the exploration and discovery of life on other planets. "We are highly conscious of the importance ...

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