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Tag: "fluorescent" at biology news

Programmable cells: Engineer turns bacteria into living computers

...u programmed E. coli bacteria to emit red or green fluorescent light in response to a signal emitted from another set of E. coli. In one experiment, the cells glowed green when they sensed a higher concentration of the signal chemical and red when they sensed a lower concentration. In a Petri dish, they formed a...

Molecular Motors Cooperate In Moving Cellular Cargo, Study Shows

...One Nanometer Accuracy. The technique can locate a fluorescent dye to within 1.5 nanometers (one nanometer is a billionth of a meter, or about 10,000 times smaller than the width of a human hair). Recent improvements to FIONA now allow scientists to detect motion with millisecond time resolution. Selvin's team ...

Harnessing microbes, one by one, to build a better nanoworld

...ssed at very low levels compared with conventional fluorescent microarrays. The system uses a chemiluminescence-detection instrument, software, and chemistries to deliver unambiguous gene results that are highly sensitive and reproducible. The PCR process and the 5' nuclease detection process are covered by pat...

Self-assembled nano-sized probes allow Penn researchers to see tumors through flesh and skin

...ylvania and the University of Minnesota has lodged fluorescent materials called porphyrins within the surface of ...Therien laboratory focused on the design of highly fluorescent compounds. Polymersomes, which were developed by Penn professors Daniel A. Hammer and Dennis Discher...

Applied Biosystems Introduces Advanced Gene Expression Service Provider Program

...ssed at very low levels compared with conventional fluorescent microarrays. The system uses a chemiluminescence-detection instrument, software, and chemistries to deliver unambiguous gene results that are highly sensitive and reproducible. The PCR process and the 5' nuclease detection process are covered by pat...

Unexpressed But Indispensable -- The DNA Sequences That Control Development

...d individual CNEs into embryos, along with a green fluorescent protein (GFP) reporter. By day two of development, 23 out of 25 CNEs injected had upregulated GFP expression, indicating interaction of these sequences with endogenous transcription factors. Different CNEs caused different regional patterns of expres...

New methods of gene delivery using lasers

...ells was then confirmed by observing the red/green fluorescent proteins produced by the ‘new?gene. The study is published today by Optics Express: http://www.opticsexpress.org ...

Novel ultrafast laser detection of cancer cells also may improve understanding of stem cells

...the old way requires a time-consuming process like fluorescent tagging or a chemical reagent. We've found we can see them immediately by light alone." The techniques could be critical to advancing early detection, diagnosis, and treatment of disease. More technically put, "To rapidly assess the health of a sin...

First real-time view of developing neurons reveals surprises, say Stanford researchers

... to right, a distinct population of neurons turned fluorescent colors to indicate their activity. Moving the square the reverse direction triggered a different population of neurons to light up. "At first we felt like we let some air out of our own tires with this finding," said Smith. His previous work had sup...

Nano-Probes Allow an Inside Look at Cell Nuclei

...f light when illuminated by a laser. Because these fluorescent probes are stable and nontoxic, they have the abil...ell or fading out -- much longer than conventional fluorescent labels. This could give biologists a ringside seat to nuclear processes that span several hours or d...

Weill Cornell Research Reveals Secrets Of Trafficking Within Cells

...activity of individual living cells by attaching a fluorescent tag to a specific cell component -- in this case clathrin. "This means that now we could suddenly look at a much broader dynamic range of activity," Dr. Ryan said. "Instead of it being an 'all or nothing' proposition, we were able to understand how ...

New research questions basic tenet of neuron function

..., the researchers labeled synaptic vesicles with a fluorescent dye and observed how and when the vesicles released neurotransmitters, both when the neurons were at rest and when they were active. From these observations, as well as data gathered from electrophysiological techniques, the researchers found two dis...

Color-blind method opens new doors in DNA sequencing

...l replicating enzymes, the DNA is tagged with four fluorescent dyes, each corresponding to a particular nucleotid...ystem so that each dye gives the same intensity of fluorescent signal, eliminating the need for further software processing to yield readable sequence information....

Timing is everything: First step in protein building revealed

...t and arelated part of the ribosome with different fluorescent chemicals. Whentwo fluorescently labeled molecules...was added to the mix."We weren't even sure the two fluorescent molecules would be closeenough together to create a FRET signal at all," says Maag. "We werevery ple...

Quantum Dots Research Leads to New Knowledge about Protein Binding in Plants

...de (CdSe) quantum dotscoated with zinc sulphide as fluorescent probes. The particles had adiameter of 6.3 nm. The...on protein.This labeled the protein molecules with fluorescent tags.Quantum dots are much more resistant to photobleaching thanconventional fluorescent markers and...

DNA Molecules Used To Assemble Nanoparticles

...ased cells. The other end of the complex carries a fluorescent protein so that the researchers can track their movement. A series of experiments using cell sorters, 3-D microscopes and other tools verified that these dendrimers hit their targets, were admitted into the cells and gave off their signaling light. ...

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