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Tag: "fluorescent" at biology news

Most common lung cancers may begin in newly discovered cells

...with another research group to develop microscopic fluorescent probes to image the unique molecular surface of BASCs and track the progress of the naturally arising tumor, Jacks said. The similar genetic activity profile of mouse tumors with K-ras mutations to the profile of human lung cancer samples make the re...

Researchers seek to discover what really happens when a virus enters the body

...e can also result from the spectral overlap of the fluorescent markers that Duca uses. Also, since the microsco... a model we developed that reflects the physics of fluorescent microscopy ?also estimates and corrects the effect of the microscope's uneven illumination and the m...

Fluorescing lab worms signal longer life spans

...sity of Colorado at Boulder scientists have used a fluorescent marker to predict the individual life spans of ide...y identical nematodes were engineered with a green fluorescent "reporter" protein coupled to a stress protein that is present in most multicellular organisms as a ...

New tool reveals secrets of migrating cells

...n on the standard technique of labeling cells with fluorescent dye and then hitting them with a laser that makes ...ight is needed to make the dye, in this case green fluorescent protein, glow. But high-frequency, short-wavelength visible light, like green, doesn't penetrate tis...

Researchers use 3-D imaging system to unveil swimming behavior of microscopic plankton

... various methods, including releasing and tracking fluorescent dye and with state-of-the-art acoustic current meters. Downward-flowing water in the ocean is always accompanied by horizontal flows, forming a convergence, or "downwelling" zone. When zooplankton swim upward against such a downward current, they fo...

Unusual antibiotics show promise against deadly 'superbugs'

... molecular marriage does take place. They attached fluorescent tags to the peptides and observed the glow in collagen that had been mixed with the smaller molecules. Exactly how and why the collagen and the peptides join is uncertain. But researchers know that collagen molecules form a distinctive triple-helix i...

Modified collagen could yield important medical applications

... molecular marriage does take place. They attached fluorescent tags to the peptides and observed the glow in collagen that had been mixed with the smaller molecules. Exactly how and why the collagen and the peptides join is uncertain. But researchers know that collagen molecules form a distinctive triple-helix i...

Using nanoparticles, in vivo gene therapy activates brain stem cells

...'s disease, for example -- took up and expressed a fluorescent marker gene, demonstrating the ability of nanoparticle technology to deliver effectively genes to specific types of cells in the brain. Using a new optical fiber in vivo imaging technique (CellviZio developed by Mauna Kea Technologies of Paris), the...

Mosaic mouse technique offers a powerful new tool to study diseases and genetics

...urn green for easier observation. "We use a green fluorescent protein," Luo says. "So now if you mutate a gene, ...eered to carry two inactivated segments of a green fluorescent protein molecule. Mice derived from these embryonic stem cells are mated to each other. As their off...

Studies reveal how plague disables immune system, and how to exploit the process to make a vaccine

...s. When that happens, those cells, when exposed to fluorescent light, glow blue instead of green. This technique enabled the team to identify the cell types targeted by the bacteria. Two days after the mice were infected, their spleens were filled with bacteria. Although the overwhelming majority of immune cell...

New Species of Coral Discovered Off Southern California

..., such as by introducing the genetic code of green fluorescent protein (GFP) into its genetic information. There the marker protein will be produced by the cellular machinery and appended to the desired site. To observe the interaction of HIV with the host cell, there had also been attempts to label the virus w...

Virologists make major step towards understanding the process of HIV infection

..., such as by introducing the genetic code of green fluorescent protein (GFP) into its genetic information. There the marker protein will be produced by the cellular machinery and appended to the desired site. To observe the interaction of HIV with the host cell, there had also been attempts to label the virus w...

Natural Killers Could Lead to New Hepatitis Treatments

...an used mice in which NKT cells were tagged with a fluorescent marker. This was accomplished by replacing the gen...face receptor called CXCR6 with the gene for green fluorescent protein. Although the CXCR6 receptor is known to be central to the function of NKT cells, its overal...

Chemical Engineer Kao Explores Antibiotic Synthesis With DNA Chips

... erythromycin-producing bacteria were infused with fluorescent dye and applied to the microarray. "This experiment revealed that the RNA transcript abundance of the erythromycin-producing genes remained higher for longer times in the Saccharopolyspora erythraea mutant strain," Kao said. Searching for mutations...

Microarrays as phenotype

...ional DNA on glass slides. Then researchers attach fluorescent labels to nucleic acids (DNA or RNA) from the cells under study. These labeled nucleic acids are allowed to bind to the DNA on the slides. Researchers then use a microscope to measure how much of a specific nucleic acid is present. Genotype is the g...

Microscopes at microscopic size

...h scientists can place biological samples. Special fluorescent chemicals are then used together with tiny light e...BioStatus has developed the research to refine the fluorescent probe technology and also to make the analysis of biological samples more sophisticated. Professor ...

Findings have implications for tracking disease, drugs at the molecular level

... at the single molecule level," said Fourkas. "The fluorescent molecules commonly used in multiphoton imaging give out only a limited amount of light, 'burn out' quickly under continuous observation, and are prone to blinking on and off. "The gold particles, however, do not blink or burn out, even after hours o...

Study: 'homemade' gene expression technology unreliable

...lacing copies of DNA or RNA molecules labeled with fluorescent dyes on the slide, and examining whether the molecules that bind to a particular gene light up when viewed with a special scanner. By interrogating thousands of genes at once, scientists can quickly pinpoint genes affected by drugs being tested to t...

Revolutionary nanotechnology illuminates brain cells at work

...eedings of the National Academy of Sciences. "The fluorescent imaging technique allows us to see living cells do... is a vibration, the same response occurs with two fluorescent dyes that have overlapping, but slightly different colors–in this case cyan and yellow versions of G...

Robot-based system developed at Carnegie Mellon detects life in Chile's Atacama desert

...-based life, such as cyanobacteria in lichens, and fluorescent signals from a set of dyes designed to light up on...d Gregory Fisher, project imaging scientist. "Our fluorescent imager is the first such system to work in the daylight while in the shade of the rover. The rover u...

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