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Tag: "fluorescent" at biology news

Cellular message movement captured on video

...n and other proteins move inside the cell with new fluorescent labels and live-cell video microscopy,” said Chien, director of the Whitaker Institute of Biomedical Engineering at the Jacobs School. The two-color labeling technique of Chien and Hu revealed that red-labeled paxillin is linked to green-labeled a...

Brightening prospects of using fluorescent nanotubes in medical applications

...INSE) have removed an obstacle that has restricted fluorescent nanotubes from a variety of medical applications, ...t can successfully produce large batches of highly fluorescent nanotubes. “Nanotubes have a number of characteristics that make them particularly suitable for u...

Bacteria ferry nanoparticles into cells for early diagnosis, treatment

...he nuclei of cells, causing the cells to produce a fluorescent protein that glowed green. The same method could b...images of diseased tissues by inserting a cargo of fluorescent molecules into tumors that are ordinarily too small to be detected, said Demir Akin, a research assi...

Surprising origin of cell's internal highways

...rotubules in human retinal epithelial cells with a fluorescent molecule, videotaped their growth and carefully followed the tracks back to their origin. "We show that not only the centrosome, but the Golgi also makes microtubules," Kaverina said. "And unlike centrosomal microtubules, which are radial and sym...

New research shows sharks use their noses and bodies to locate smells

...lso tested the sharks under two light conditions – fluorescent and infrared – and in two sensory conditions – with their lateral lines intact or lesioned by streptomycin," explained Gardiner. According to the researchers, streptomycin, an antibiotic, interferes with the normal function of motion sensitive "h...

Catching cancer's spread by watching hemoglobin

...ution) and does not require any contrast agents or fluorescent markers (unlike most other high-resolution vessel-imaging techniques). Clinically, the imaging technique can potentially be used to detect the spread of cancer, since angiogenesis—the growth of new blood vessels from existing ones—often signals ...

Technique monitors thousands of molecules simultaneously

...dy that recognizes the receptor and is tagged to a fluorescent label. The washing step risks removing a bound receptor if it does not bind the molecular key strongly enough. But, with an electrochemically addressable computer chip, provided in great abundance by one of his sponsor's, CombiMatrix in Seattle, Moel...

pHLIP, a novel technology to locate and treat tumors

... The researchers demonstrated that by attaching fluorescent probes to a pHLIP peptide, tumors could be detected. They expect that by attaching and delivering active agents with pHLIP, that tumors may be able to be treated. Targeting is based on the fact that most tumors, even very small ones, are acidic as a ...

Newborn neurons like to hang with the 'in' crowd

...chers injected a virus carrying the gene for green fluorescent protein into the hippocampus, a brain region harbo... born neurons infected with virus were marked by a fluorescent dye enabling the researchers to follow their fate over time as they tried to get accepted into the e...

New technique will produce a better chromosome map

...accurate chromosome map, researchers will next use fluorescent immunostaining of proteins that bind to specific DNA sequences. These landmarks will help them tease out the relationship of the sequence to the physical structure. The new approach will allow scientists to answer fundamental questions about chrom...

New Brandeis research sheds light on memory by erasing it

...ppens to the CaMKII after it is attacked. By using fluorescent forms of CaMKII, it will be possible to determine whether the kinase leaves the synapse after inhibitor is applied. This provides a way to directly visualize the forgetting process and complements previous work done in Lisman's laboratory showing tha...

Survival of the rarest: Fruit flies shed light on the evolution of behavior

...Fitzpatrick "tagged" one of the types with a green fluorescent protein that glows under ultraviolet light. Then, over the course of a year, Fitzpatrick sat in a darkened room for several hours a day counting glowing larvae under a microscope. The researchers found that when the fruit fly larvae were competing...

Fast and slow -- How the spinal cord controls the speed of movement

...colleagues injected the fishes?spinal cords with a fluorescent dye, which then lit up when calcium ions flooded in as the nerve cells activated. A confocal microscope with lasers allowed the researchers to image the cells at very high resolutions. Using this set up, they watched nerve cells light up as the anima...

Deconstructing brain wiring, one neuron at a time

...eds of surrounding cells, turning them brilliantly fluorescent green. While these experiments were conducted using slices of brain, it is possible to produce transgenic mice that will express specific genes in a targeted class of neurons, Callaway says. "All neurons of the type we select will then express the...

Lighting up life: Cold Spring Harbor Protocols presents tips for creating glowing plants

...hem to radiate a brilliant green color. This green fluorescent protein (GFP) has allowed biologists to make many new discoveries regarding how living cells function. But one kingdom of life—plants—has presented special challenges to GFP detection: plants harbor tough cell walls and enormous subcellular structur...

Researchers develop marker that identifies energy-producing centers in nerve cells

...er functioning of the central nervous system. This fluorescent marker protein may shed light on brain cell defect...echniques, the researchers have produced mice with fluorescent protein markers that identify only the mitochondria in neurons. These structures light up with a gre...

Sandia researchers take new approach to studying how cells respond to pathogens

... Proteins in the cells of interest are tagged with fluorescent molecules, essentially colored dyes. The dyes range from green to red and give researchers the opportunity to track proteins and see, for example, the dynamic cellular production of proteins or protein-binding processes inside or on the surface of th...

Enhancing activity of marijuana-like chemicals in brain helps treat

... which the various cell types were labeled with a fluorescent protein that glows vivid green under a microscope. Having an unequivocal way to identify the cells allowed them to tease apart the functions of the different cell types. Malenka's lab has long studied how the communication between different neu...

Imaging techniques permit scientists to follow a day -- or four -- in the life of a cell

...complex assays--including laser photobleaching and fluorescent speckle microscopy--that yield specific insights into cellular processes. A second freely available protocol ( http://www.cshprotocols.org/cgi/content/full/2007/1/pdb.prot4660 ) outlines the construction and use of an enclosed microscope chamber. ...

Sheffield scientists light up bacteria

...he new method will use a polymer which will give a fluorescent signal when it encounters bacteria, allowing scientists to easily identify infected wounds much earlier than using conventional methodologies. The new technology will be of immediate benefit to healthcare industries in general, as well as those in...

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