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Tag: "fluctuations" at biology news

Gene Therapy For Parkinson's Disease Moves Forward In Animals

...at instead of taking pills that create detrimental fluctuations of L-dopa levels, a continuous, therapeutic dose would be better for you. As for efforts to reverse impaired movements in rats, scientists used 33 animals with severe dopamine depletion and transferred a gene to provide a source of L-dopa production...

The very unexpected life and death of a leukemic cell

...y may vary over time and this may be the result of fluctuations in birth and/or death rates of the CLL cells. This challenges the dogma that CLL is a purely accumulative disorder where leukemic cells accumulate because they cannot die. Clearly CLL is a disease in which there is a dynamic interplay between rates ...

Gene therapy for Parkinson's disease moves forward in animals

...at instead of taking pills that create detrimental fluctuations of L-dopa levels, a continuous, therapeutic dose would be better for you. As for efforts to reverse impaired movements in rats, scientists used 33 animals with severe dopamine depletion and transferred a gene to provide a source of L-dopa production...

Low level of extinction during ice age linked to adaptability

...this era were singularly equipped to endure severe fluctuations in temperature and sea levels. Those that were not...aid. "The other competing hypothesis is that large fluctuations of sea level, driven by the melting and reforming of glaciers, disrupted marine communities, and the...

Scripps scientists find potential for catastrophic shifts in Pacific ecosystems

... Pacific's biological systems exhibited shift-like fluctuations consistent with "nonlinear" mechanisms. Measuring ...les. This finding means that suspected regime-like fluctuations in the North Pacific physical system are for all practical purposes wiggles that are best modeled by...

Random gene expression may drive HIV into hiding

Random fluctuations in gene expression can influence the fates of cell...t Arkin had done in the 1990s, showing that random fluctuations in viral gene expression can influence latency in a bacterial virus, Weinberger wanted to see if the...

Millennium Ecosystem Assessment: Many of 2 billion dryland dwellers at risk as land degrades

...ivity can increase their vulnerability to seasonal fluctuations and droughts." "Population growth, inappropriate policies, and some aspects of globalization are the main drivers that lead to unsustainable pressure on dryland ecosystems," he says. Adds co-author Uriel Safriel of Hebrew University of Jerusalem, a...

Space matters: Estimating species diversity in the fossil record

...ect. These results, they argue, suggest that many fluctuations in diversity seen in fossil analyses actually arise from the species-area effect and are not actually the result of true changes in the distribution of species. Given the lack of uniform geographic sampling in paleontological data, the impact of this...

York scientists warn of dramatic impact of climate change on Africa

...rtment studied the likely impact of future climate fluctuations on the continent by modelling the responses of more than 5000 plant species to predicted climate changes. Dr Jon Lovett, who led the research, said: "The results were extraordinary ?plants migrate out of the Congo rainforests and there is a massive ...

Scientists create digital bacteria to forge advances in biomedical research

...them to study the relationship between biochemical fluctuations within a single cell and the cell's behavior as it...cument the connection between internal biochemical fluctuations and cellular behavior. "The belief is that these fluctuations are going to be reflected in the behav...

New law for resolution allows unprecedented sharpness in fluorescence microscopy

...tal implications for methods that use fluorescence fluctuations to study the reaction kinetics of molecules in solutions. The smaller the focal volumes, the more effective and sensitive are these methods. Fluorescence fluctuation methods were also limited by diffraction as a result. Therefore, in a fourth study [...

Amphetamines reverse Parkinson's disease symptoms in mice

...herapy wanes with time, and patients often develop fluctuations in motor performance and other adverse reactions. In the current study, the researchers treated mice unable to recycle dopamine with a drug that also prevented them from manufacturing the brain messenger. The brains of the mice therefore lack detect...

Ancient anthropoid origins discovered in Africa

...in magnetic fields in the sediments due to ancient fluctuations in the earth's magnetic fields. According to Simons, other anthropoids exist at BQ-2 and will soon be described, The latest fossils of the new species consist of tiny teeth and jaws, whose shapes yield critical clues about the species whose mouths t...

Researchers quantify more noise in gene expression

...f variation at the basic level of life: unscripted fluctuations within individual cells and variations between ide...ave detected and classified significant downstream fluctuations that result from this source of 'intrinsic noise' in gene expression." Hasty leads a team of resear...

Team led by Carnegie Mellon University scientist finds first evidence of a living memory trace

...?the memory trace ?from what appeared to be random fluctuations of neural activity. "The trace is like a fingerprint that disappears over time. It's strongest after the honeybee's initial exposure to an odor, but you can still detect its signature features minutes afterwards," said Galán. A future question tha...

Phenotype is influenced by nature, nurture and noise

...l biologists are proving otherwise. The fine-grain fluctuations we see in the genetic regulation within single cells may lead to new insights about variability at the level of a fly, cat, or human." Changes in a cell's phenotype may be triggered by environmental factors, by programmed genetic instructions, or mo...

Animal models show that anabolic steroids flip the adolescent brain's switch for aggression

... or without steroid abuse. "Linking aggression to fluctuations in vasopressin makes it an important neurotransmitter to target for pharmacotherapy," he says. ...

Nanopore method could revolutionize genome sequencing

...nd computer modeling of the motions and electrical fluctuations of DNA molecules to determine how to distinguish e...dicular to the DNA strand to reduce the structural fluctuations of DNA while it moves through the pore, thus minimizing the noise. "If nature was very unkind, then...

Alaska seal pup diet may hold key to decline of population

...o far have been surprising: growth rates, seasonal fluctuations in body mass, and percent body fat have been generally independent of the seal's diet. Instead, the starting weight has been the critical predictor of whether the seal would add body mass and body fat, Polasek explained. Seals weighing less than 26 ...

Atmospheric ozone recovering in mid-latitudes, report shows

...rs had to account for long- and short-term natural fluctuations in ozone concentration, Cunnold noted. One such fluctuation is an 11-year solar cycle, and another is a two-year oscillation that occurs in the tropics, but affects ozone in other latitudes because of atmospheric transport. Despite the natural fluctu...

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