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Tag: "flexibility" at biology news

Breakthrough Microarray-based Technology for the Study of Cancer

...ampered by inadequate sensitivity, specificity and flexibility of themicroarray platforms. As detailed in the PNAS paper, Agilent'sbreakthrough is founded on the modification of its gene-expressionprofiling microarray technology to improve its utility for DNA analysisapplications. This new platform provides high...

Nanogen Issued Patent for Electronic Microarray With Memory

...centrate DNA or RNA, providing accuracy, speed and flexibility for developing molecular diagnostic tests. Storing critical voltage information allows for precise control of the biological molecules during analysis and increases data management efficiency by tracking test site activation and array usage directly ...

UCSD discovery may help extend life of natural pesticide

...these parasites." Griffitts and Aroian credit the flexibility of the roundworm C. elegans as an experimental system, particularly the ease of manipulating it genetically, in making it possible to find and characterize the structure of the long sought-after Bt receptor. However, their results apply to insects as...

Scientists solve structure of key protein in innate immune response

...ommodated in the pocket due to its large size, the flexibility of its rim, and the multiple grooves available for ligand binding. The researchers also discovered that mutations that interfere with LPS signaling cluster in a separate area near the pocket suggesting that the areas around the pocket are important i...

NIH Calls on Scientists to Speed Public Release of Research Publications

...'s public health mission, with the need to provide flexibility for authors, their institutions, and publishers in...peer review process. The policy gives authors the flexibility to designate a specific time frame for public release ?ranging from immediate public access after fi...

Buying Time Through Hibernation on Demand

...ersibly demonstrated the widest range of metabolic flexibility that anyone has ever seen in a non-hibernating animal," Roth said. "The cool thing about this gas we're using, hydrogen sulfide, is that it isn't something manufactured that we're taking down from a shelf ?it isn't 'better living through chemistry' ...

U-M team recovers ancient whale in Egyptian desert

...ersibly demonstrated the widest range of metabolic flexibility that anyone has ever seen in a non-hibernating animal," Roth said. "The cool thing about this gas we're using, hydrogen sulfide, is that it isn't something manufactured that we're taking down from a shelf ?it isn't 'better living through chemistry' ...

Advancements In Genomics Foster Deep Sea Discoveries

...atural barometer-like mechanism, which adjusts the flexibility of its membranes to cope with different levels of pressure. “There’s a protein within the membrane that gets squeezed when the cells experience higher pressure, and that triggers a signal transduction event that activates the expression of genes tha...

Supercomputers to focus brains on AIDS dilemma

...iscovered that there is a great deal of unexpected flexibility in this binding region, indicating that instead of...ies of drug candidates that rely on the remarkable flexibility revealed by the McCammon group's simulations in the integrase binding site. The first of these compo...

Brain May Be Less Plastic Than Hoped

...al cortex of the adult primate brain displays less flexibility in response to retinal injury than previously thought, according to a new study published in the May 19, 2005, issue of the journal Nature. This may have implications for other regions of the brain, and the approach the investigators used may be a ke...

Software Tool for Converting Scientific Text into a Database of Functional Relationships

...of MedScan work." The new version of MedScan adds flexibility on the level of entity recognition and information extraction. It has become simple to customize dictionaries, and extract new types of relationships by adding or editing linguistic patterns. MedScan users can create information extraction pipelines ...

Researchers test new therapy for advanced melanoma

...ogy Program at Moffitt. "Gene therapy gives us the flexibility to introduce a huge variety of potential targets for treatment, but its major limitation has been getting the gene into the cancer. If electroporation can deliver the gene to these tumors reliably and without serious side effects, melanoma and other ...

The making and breaking of microtubules

...th of cancer cells. "Nucleotide-dependent bending flexibility of tubulin regulates microtubule assembly," by Hong-Wei Wang and Eva Nogales, appears in the 16 June 2005 issue of Nature. ...

Promiscuous Catalytic Activity Possessed by Novel Enzyme Structure

...hat had never been seen before. The key to Orf2’s flexibility seems to reside in the active site, the region of the enzyme where the small aromatic molecules bind. In many enzymes, the structure of the active site only allows one specific molecule to interact with it, like a key fitting into a lock. But the sci...

Stem cell training program to make its Stanford debut

...hat had never been seen before. The key to Orf2’s flexibility seems to reside in the active site, the region of the enzyme where the small aromatic molecules bind. In many enzymes, the structure of the active site only allows one specific molecule to interact with it, like a key fitting into a lock. But the sci...

'Jumping genes' contribute to the uniqueness of individual brains

...ys. "This mobility adds an element of variety and flexibility to neurons in a real Darwinian sense of randomness and selection," says Fred H. Gage, Professor and co-head of the Laboratory of Genetics at the Salk Institute and the lead author of the study published in this week's Nature. This process of creating...

Gap-climbing fruit flies reveal components of goal-driven behaviors

... of the three motor components. This goal-directed flexibility of the fly's motor programs characterized in the new work profoundly changes our view of how insect behavior is composed and employed in response to the environment. ...

Nanotubes inspire new technique for healing broken bones

...scaffolds, the high mechanical strength, excellent flexibility and low density of carbon nanotubes make them idea...xpect that nanotubes will improve the strength and flexibility of artificial bone materials, leading to a new type of bone graft for fractures that may also be imp...

Surgical Robot 'Scrubs In' At UNC, May Be More Precise Than Conventional Surgery

...hat the surgeon has, and its instruments have more flexibility to perform the delicate nerve sparing and sewing parts of the procedure," he said. Patients, in turn, recover quickly and are able to resume their normal life within days of major surgery instead of months, Boggess said. "The robot provides the lap...

Screen all at risk for HIV, plus pregnant women

...hat the surgeon has, and its instruments have more flexibility to perform the delicate nerve sparing and sewing parts of the procedure," he said. Patients, in turn, recover quickly and are able to resume their normal life within days of major surgery instead of months, Boggess said. "The robot provides the lap...

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