Deficient DNA Repair Capacity Associated With Increased Risk Of Breast Cancer
...r capacity in the nucleotide excision pathway that fixes DNA alterations known as bulky DNA adducts is associated with breast cancer risk, Regina M. Santella, Ph.D., of the Columbia University Mailman School of Public Health in New York, and colleagues analyzed cell lines generated from blood samples taken...Tsunami-damaged coral reefs should be left to recover naturally, say scientists
...'s School of Biology, added: "There are many quick fixes on offer but scientific evidence suggests that in most cases these would not be a good use of scarce resources and could actually harm surviving reefs. We need to find a long-term, sustainable solution for restoration. "We're advocating a cleaning up...Stressed cells spark DNA repair missteps and speed evolution
...ound the newly synthesized genetic material. "It fixes the hole in the DNA by copying similar information," said Rosenberg. However, when the process goes wrong, the repair process introduces errors into the DNA. When graduate student Rebecca G. Ponder set up a system so that she could control where th...Hot-spring bacteria flip a metabolic switch
...s the nitrogenase complex--the enzyme factory that fixes N2. Other organisms have found creative solutions to this dilemma. For example, plants rely on symbiotic N2-fixing bacteria that live in their roots, far away from the photosynthetic leaves. A different type of cyanobacteria grows in multicellular st...Microbe fixes nitrogen at a blistering 92 C
...geothermally heated sand near an Italian beach and fixes nitrogen at temperatures up to 64 C. Nitrogen is necessary for all life because it is an essential part of amino acids and proteins. To be used by organisms, gaseous nitrogen must be converted to other compounds, or "fixed," which can only be done ......wn reproduction. The DNA damage response normally fixes DNA errors caused by radiation or other environmental factors, or mistakes accidentally introduced when cells copy their genetic material prior to dividing. In the murine (or mouse-infecting) herpes virus they studied, researchers at Washington Un...