New path from estrogen to survival in breast cancer cells described
...to. In this way, they could use SNEP8 "as bait" to fish for protein complexes held together by NEDD8. They first found that BCA3 binds to SENP8 and was modified byNEDD8, and then discovered that this complex affects NFkB signaling. It does this by binding on to p65, one of the two proteins that make up...How does a zebrafish grow a new tail?
...cells and is a very intricate structure. It is the fish version of an arm or leg. The question of how col...ore about the remarkable ability of amphibians and fish to re-grow complex parts might provide the information necessary to create treatments for people who...Stormy days ahead for coral reefs
...leaching"); and overfishing, which can deplete the fish that eat seaweeds and dead coral and keep the reef clear for the next generation of corals. "Regardless of whether we think of more severe storms as a looming threat or just the ramping up of a natural cycle, one thing is certain," says Dr Conn...Jumping gene could provide non-viral alternative for gene therapy
...asleep" in fish. They also looked at Tol2, another fish transposon, and Mos1, found in insects. The piggyBac transposon, which has close relatives in the human genome, is widely used to genetically modify insects. Sleeping Beauty has been used to correct hereditary diseases, including hemophilia, in a ...Common carp sheds new light on surviving in extreme environments
...r even kill lesser creatures. This is because the fish has evolved in small-to-medium sized ponds in a harsh continental-type climate in Asia where the winters are very cold and the summers are hot and steamy. "Its ability to cope with such extreme conditions of temperature, lack of oxygen and dirty, ...Mobile DNA part of evolution's toolbox
...a small segment of DNA in the genome of a primeval fish may have been crucial to the transition of ancient...match was to DNA from the coelacanth -- an ancient fish thought to have gone extinct millions of years ago until a live specimen was caught in 1938 off the ...Electric fish in Africa could be example of evolution in action
... for shapes and patterns of electricity created by fish in the water. They know from their previous research that the various groups of local electric fish have different DNA, different communication patterns and won't mate with each other. However, they n...Report warns about carbon dioxide threats to marine life
...structures that provide habitat for many important fish species, particularly in the coastal waters of Alaska. The report outlines future research to understand this consequence of climate change. While scientists cannot yet fully predict how much marine calcification rates will change in the future, the...Choosy females make colourful males
Female fish prefer brightly coloured males because they are ea...tch researcher Martine Maan following her study of fish speciation in the East African Lakes. Environmental variation subsequently leads to differences in p...Pollen proves beneficial for northern lakes
...r forage fish, the production of harvestable sport fish may also rise, all thanks to pollen. Since climate also affects annual pollen production predicted climate change scenarios could affect the productivity of northern lakes by altering the magnitude and timing of delivery of this important source of...Major initiative proposed to address amphibian crisis
...n turn serve as part of the food supply for birds, fish and other animals. The demise of entire species also eliminates their possible use in biomedicine and biotechnology. One of the leading problems is a fungus that causes an infectious disease called chytridiomycosis, the researchers said in their S...Female guppies risk their lives to avoid too much male attention
...and habitats," explains Croft, who points out that fish are not the only species who display this social characteristic. "In many ecosystems, predators are the first to go extinct, and our work shows that this may have many, perhaps unexpected, effects. In this case, females may suffer more sexual harassm...Compound in dairy products targets diabetes
...e "bad" fats. CLA, whose effect is very similar to fish oil, a source of "good" fat, could prove beneficial against Type-2 diabetes. "And compared to the synthetic drugs used to treated this disease, CLA does not cause weight gain and may in fact decrease overall body fat," says Vanden Heuvel, who has...Precision biochemistry tracks DNA damage in fish
Like coal-mine canaries, fish DNA can serve as a measure of the biological impac... pollutants in water and sediment on the health of fish in the lower Duwamish River. The Duwamish flows through an industrialized section of south Seattle, ...Researchers appeal for new regulations to save coral reefs from live fish trade
... are calling for tighter controls on the live reef fish trade, a growing threat to coral reefs, in letters...of the reefs is being compromised by the live reef fish trade, a serious threat that has prompted scientists to call for tighter regulations on the exploita...Jellyfish dominate fish in over-harvested Namibian waters
... have found that jellyfish have actually overtaken fish in terms of the biomass they contribute to this oc...ela. In the past, this region has offered abundant fish stocks, thanks largely to its being served by cool, nutrient-rich upwellings occuring along the cont...Harmful Algal Blooms monitored from space in Chile
...n water, causing physical or biochemical damage to fish and shellfish. Early detection of Harmful Algal Blooms (HABs) allows fish farmers to make timely key decisions in order to minimise the damage to aquaculture. To aid in this ...Global warming may have damaged coral reefs forever
...m impact of sea temperature rise on reef coral and fish communities. Large sections of coral reefs and m...s just 7.5 per cent. The survey showed that four fish species (a type of butterfly fish, two types of wrasses and a type of damsel fish) are possibly alre......go, early animals had 13 Hox genes. Then, in jawed fish ?the last common ancestors of modern vertebrate animals ?each Hox gene had split into four, so 13 became 52. Later, duplicate Hox genes either mutated in a way that proved useful, or vanished because they were redundant, so today in humans and other...Bedsores and bald hides: Novel roles revealed for a 'scaffolding' protein
...r nearest neighbors, the research team was able to fish out K17 and all other proteins stuck to it. One of these, called 14-3-3(sigma) not only binds to K17, but has been thought to activate the Akt/mTOR pathway to increase protein synthesis and cell size. In further experiments, the investigators reintro...