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Tag: "first" at biology news

Chemists create 'Superbowl' molecule; May lead to better health

...lass of artificial bowl-shaped molecules that were first developed in the 1980s to mimic naturally occurring enzymes, which facilitate molecular synthesis and transport within the body. Over the years, these bowl-shaped molecules have been extensively studied and refined by chemists for their wide range of...

Wisconsin scientists grow critical nerve cells

...n transplanted into a living animal. The team will first test the neurons in chicken embryos. While the new results are promising and provide access to critical cells that may one day be used in therapy, it will likely be many years before they can be tested in humans, Zhang says. ...

New push for public health, AIDS spending at African Union summit

...n the US Food and Drug Administration approved the first ARV cocktail, which could open the taps on the promised $US15 billion that President George W Bush promised two years ago for the fight against AIDS. ...

Man and mouse share genome structures

...and human development. The research team includes first author Bradley Bernstein, recipient of a Howard Hughes Medical Institute (HHMI) physician postdoctoral fellowship who works in the Harvard University laboratory of HHMI investigator Stuart L. Schreiber. Other co-authors are from the Broad Institute o...

Scientists ID molecular 'switch' in liver that triggers harmful effects of saturated and trans fats

...ular mechanism in the liver that explains, for the first time, how consuming foods rich in saturated fats and trans-fatty acids causes elevated blood levels of cholesterol and triglycerides and increases one's risk of heart disease and certain cancers. In the Jan. 28 issue of Cell, scientists led by Bruce...

A new mechanism of regulating RNA degradation

...tion at the RNA level is even more complex than we first imaginated... As any dedicated video game player knows, the first requirement for using a weapon or tool is finding it. And it is no different for cell biologists and...

FDA Approves Human Hookworm Vaccine for Phase I Safety Trials

...tion at the RNA level is even more complex than we first imaginated... As any dedicated video game player knows, the first requirement for using a weapon or tool is finding it. And it is no different for cell biologists and...

Spleen may be source of versatile stem cells

...adult mammal."Co-authors of the SAGE KE report are first author Shohta Kodama, MD,PhD, of the MGH Immunobiology Laboratory, and Miriam Davis, PhD, ofGeorge Washington University. The group's research is supported bygrants from the Iacocca Foundation. Founder Lee Iacocca is alsospearheading an effort to rai...

Genes In The Interferon System Important In Systemic Lupus Erythematosus

...of HumanGenetics. "These findings are probably the first genetic pieces of ahuge 'interferon puzzle,' with whose help it will be possible todiscover the mechanisms behind the disease SLE, and maybe otherautoimmune diseases at the molecular level," says Professor LarsRönnblom. "Itis remarkable that by stud...

UCSB scientists probe sea floor venting to gain understanding of early life on Earth

...ns, which has been occurring ever since the oceans first formed four billion years ago. Conditions below th...f the global mid-ocean ridge system. These are the first reported manifestation of hydrothermal systems associated with abyssal hills on the flanks of a fast...

Quantum Dots Research Leads to New Knowledge about Protein Binding in Plants

...d them under a confocalmicroscope.This is the very first time that Quantum Dots have been utilized forlive imaging in plant systems. The study opens the door for thepotential use of Quantum Dots in live imaging of plant cells andprovides valuable understanding of the mechanism of interaction betweenthe pol...

Source of molecular triggers in cutaneous T cell lymphoma identified

...nd his colleagues at the National Cancer Institute first identified CTCL as a separate category of lymphoma thirty years ago. The Yale research group reported that, like all T cells, the cancerous CTCL cells require antigenic stimuli delivered by specialized dendritic cells of the epidermis, referred to a...

Dysentery uses 'sword and shield' to cause infection

...and one of the researchers, comments: "This is the first description of bacteria able to use this 'sword and shield' approach, showing how dysentery is able to infect the body so effectively. We have shown why the bacteria can avoid being destroyed by the body's immune responses through the expression of a...

Topical treatment shown to inhibit HIV and herpes simplex virus infection

... Retroviruses and Opportunistic Infections, is the first to show that a gel can retain anti-viral activity within the human vagina. The study, which was funded by the National Institutes of Health (NIH) investigated the efficacy of PRO 2000, a topical microbicide under development by Indevus Pharmaceutica...

Priming embryonic stem cells to fulfill their promise

...icpromise, scientists believe that stem cells must first be coaxed todifferentiate, or mature, into precurs...ls to embryonic stem cells, we may be able for the first time tostudy all the dimensions of the niches required to very specificallycontrol embryonic stem ce...

Growth in the sea comes down to a struggle for iron

...Nature that oceanographer John Martin reported the first series of iron experiments that indicated iron was...el. The Americans' interest stems in part from the first SEEDS experiment in 2001. Japanese scientists had recorded the largest phytoplankton bloom of any of...

New, automated tool successfully classifies and relates proteins in unprecedented way

For the first time, researchers haveautomatically grouped fluorescently tagged proteins fromhigh-resolution images of cells. This technical feat opens a new way toidentify disease proteins and drug targets by helping to show whichproteins cluster together inside a...

New binding target for oncogenic viral protein

...arge T," explained Dr. Markus Welcker, the study's first author. The research appears as the "Paper of the Week" in the March 4 issue of the Journal of Biological Chemistry, an American Society for Biochemistry and Molecular Biology journal. DNA tumor viruses proliferate by hijacking their host cell's DN...

Poor prenatal nutrition permanently damages function of insulin-producing cells in the pancreas

...he other group also was fully nourished during the first two weeks but undernourished during the third week, restricted to only half the amount. It had a dramatic effect. At birth, their babies weighed 23 percent less than the control group. After delivery, all babies nursed and all mothers ate a full die...

Fox Chase Cancer Center scientists identify immune-system mutation

...n the Feb. 24 issue of Nature. Kappes' laboratory first discovered the mice with this naturally occurring defect in Fox Chase's laboratory animal facility in 1997. Known as "helper deficient" or HD mice, they are proving to be useful for exploring the pathways of lymphocyte development, according to Kappe...

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