Combination therapy leads to partial recovery from spinal cord injury in rats
... conduction from the brain to the leg muscles. The finding may eventually lead to new ways of treating spinal...temore. "It is a proof of principle." Although the finding is promising, much work remains before such a technique could be used in humans. The study appears i...Small worm yields big clue on muscle receptor action
... it to the synapse," she added. Richmond said the finding might have direct relevance to humans because the ACR-16 receptor is very similar to the alpha-7 nicotinic receptor in the human brain. ...Study: Well-known protein helps stem cells become secretory cells
... Described in the May 15 issue of Development, the finding improves understanding of how cells become specialized for secretion, which is a critical ability of certain glands and cell types in organisms from insects to humans. The researchers discovered that a protein called CrebA single-handedly controls t...UCR chemist part of team identifying new areas of gene regulation
...yeast governs genetic expression and repression, a finding that could be repeated in cells of other organisms. Zhang, an academic coordinator at the Mass Spectrometry Facility of the Department of Chemistry at UCR, worked with Feng Xu and Michael Grunstein of the Department of Biological Chemistry at the Da...Where Bacteria Get Their Genes
...rch from The University of Arizona in Tucson. The finding has important biomedical implications because such gene-swapping, or lateral gene transfer, is the way many pathogenic bacteria pick up antibiotic resistance or become more virulent. "To maintain effective treatments and develop new antibiotics, it'...Speak up: Louder neurons form more connections
...which branches have the most electrical activity—a finding that could help to explain how early experiences guide brain development. The work, published in the April 21 issue of Nature, takes advantage of tiny, see-through zebrafish. Stephen Smith, PhD, professor of molecular and cellular physiology at the ...Confirmation of human protein interaction data by human expression data
...which branches have the most electrical activity—a finding that could help to explain how early experiences guide brain development. The work, published in the April 21 issue of Nature, takes advantage of tiny, see-through zebrafish. Stephen Smith, PhD, professor of molecular and cellular physiology at the ...Using nanoparticles, in vivo gene therapy activates brain stem cells
...lso manipulate the behavior of brain cells. Their finding that the nanoparticles successfully altered the development path of neural stem cells is especially intriguing because of scientific concerns that embryonic stem cells may not be able to function correctly since they have bypassed some of the develop...Researchers discover mechanism for multiplying adult stem cells
...ar and ovarian cancer. Still, the most provocative finding was that "Oct4 causes tumors by preventing adult stem cells in these tissues from differentiating," says Hochedlinger. In other words, with Oct4 active, the stem cells could replicate themselves indefinitely, but could not produce mature tissue. One...Enlisting genomics to understand flu evolution
...tudy in the open-access journal PLoS Biology. This finding may help scientists make better predictions about which viral strains will attack during upcoming flu seasons and design more effective flu vaccines. In the first large-scale effort to sequence the flu genome, Edward Holmes, David Lipman, and collea...Scripps research scientists identify infertility molecule
...nging prostaglandin levels. This is a significant finding because low implantation rates are one of the major issues facing women who use assisted reproductive technologies, and nobody has ever considered LPA signaling to be involved in implantation. If the same pathway turns out to be relevant in human emb...Researchers use 3-D imaging system to unveil swimming behavior of microscopic plankton
...f fishermen catches can depend on their success at finding those patches. For almost a century ocean scientists have suspected that these patches form when the zooplankton swim against the ocean currents. In all those years, however, an understanding of zooplankton swimming response to ocean currents has re...Caloric restriction won't dramatically extend life span in humans: UCLA research
... their reproductive system," said Phelan, citing a finding from his dissertation. A normal rodent reaches maturity at one month of age, and begins reproducing its body weight in offspring every month and a half. If humans shut off reproduction by severely limiting calories, "our reduction in wear and tear on...Discovery of an American salamander where it shouldn't be: Korea
...ts, though actively studying other salamanders and finding other new species, they did not expect to find a family of salamanders never before seen in Asia. "People have gone on expeditions looking for terrestrial salamanders, in places like Kazakhstan and other Central Asian republics," said Wake. "They di...Genomic sequences processed in minutes, rather than weeks
...-- bringing us one step closer to curing diseases, finding safer ways to clean the environment and protecting the country against biological threats. ScalaBLAST is a sophisticated "sequence alignment tool" that can divide the work of analyzing biological data into manageable fragments so large data sets can...Researchers develop new method for facile identification of proteins in bacterial cells
... mixture of hundreds of proteins can be likened to finding the proverbial needle in the haystack; this task can be performed much faster and more economically if you have more needles--and that's exactly what our method is based on," explained Dr. Halden. "Instead of spending a lot of time and resources on e...Major advance made on DNA structure
...ences. Another important part of this study is the finding that the process of DNA crystallization does not distort its structure. "Essentially, this is a proof of concept, a demonstration that this approach to studying DNA structure will work, and can ultimately be used to help understand biology," Ho said...Fluorescing lab worms signal longer life spans
...nse systems present in an organism," Rea said. "By finding them, we should ultimately be able to find what makes an animal robust to many different insults." Johnson authored a milestone paper in 1988 showing that mutating a single gene in roundworms could double their life span -- the first evidence that t...Scientists discover that three molecules may be developed into new Alzheimer's drugs
...ed in the brains of patients with Alzheimer's. The finding is promising news for the development of drugs for the disease. Ken Kosik, co-director of the Neuroscience Research Institute at the University of California, Santa Barbara, headed the effort to find these molecules. The results of the study are pub...Scientists at Galileo Pharmaceuticals confirm inflammatory response linked to glucose levels
...ed in the brains of patients with Alzheimer's. The finding is promising news for the development of drugs for the disease. Ken Kosik, co-director of the Neuroscience Research Institute at the University of California, Santa Barbara, headed the effort to find these molecules. The results of the study are pub...