Enlisting genomics to understand flu evolution
...enough samples from around the world," he adds, to find the benign virus strain that will become next season's scourge. The more genomes scientists collect--and the more refined the tools of genomics become--the greater the chances of developing more effective vaccines. Citation: Holmes EC, Ghedin E, Mil...Achilles heel of the herpes virus possibly found
... away from being able to use this new knowledge to find effective drug candidates, this is a very exciting... herpes virus. They searched the genome library to find genes essential to HSV infection, isolated the B5-coding sequence, and figured out how to get pig ce...Researchers use 3-D imaging system to unveil swimming behavior of microscopic plankton
...r in the Marine Physical Laboratory at Scripps. "I find it fascinating and remarkable that we can capture the reflection of such tiny creatures in three dimensions from two meters away." The divers frequented the underwater setup to sample the animals, reorient the transducer and measure the vertical cur...Discovery of an American salamander where it shouldn't be: Korea
...rsenia koreana, in the May 5 issue of Nature. The find suggests that the lungless salamanders are more wi... Korean frogs and salamanders, who heard about the find a few weeks ago. "The closest relative to the critter they are reporting for the first time is proba...Biologists determine genetic blueprint of social amoeba
...ch we will relate the gene function information we find to humans," Kuspa says. "It makes Dictyostelium a better model for looking for targets against which drugs can act." Key collaborators in the project at Baylor included Richard Gibbs and George Weinstock, co-directors of Baylor's Human Genome Sequen...Newly discovered genetic disease sheds light on body's water balance
...on." First, Gitelman and his colleagues worked to find an innovative treatment for the two young patients. "When adults retain too much water we can treat them by restricting fluid intake," he said. "We can't do that with infants -- almost all of their nutrition comes in liquid form." The physicians wer...Researchers develop new method for facile identification of proteins in bacterial cells
...d resources on eliminating the background noise to find the signal, our method increases the signal upfront so that it stands out above the background noise. By forcing an up-regulation of enzyme expression in the bacterium of interest, our target can be identified amidst all of the other cell components,...Novel compounds show promise as safer, more potent insecticides
...ath risks and there’s a growing effort underway to find safer replacements. Targeting the ryanodine receptor may offer a promising alternative, researchers say. Ryanodine, a natural alkaloid discovered years ago in a species of tropical plant, has been used to study muscle physiology in a wide variety of...The genetic origins of corn on the cob
...has a spiky top like corn, so we were delighted to find that they have similar profiles of ramosa1 activity," says Martienssen. ...$6.5 Million Grant for Microarray Center at Yale School of Medicine
...has a spiky top like corn, so we were delighted to find that they have similar profiles of ramosa1 activity," says Martienssen. ...A virus-like hitchhiker may trigger bacterial meningitis
...- known as 'hyperinvasive' strains -- occasionally find their way into the blood stream and then into the brain, where they trigger a potentially fatal immune response (meningitis). Tinsley and colleagues have now discovered that many hyperinvasive stains of N. meningitidis contain a bacteriophage (a vir...Scientists turn tobacco against cancer
...tibody is expensive, and researchers would like to find alternatives. Dr. Koprowski, Dr. Ko and their co-w...d prevent disease in infected mice. They wanted to find out if plant-made antibodies could be effective for cancer immunotherapy. They first showed that pl...Tufts researchers shine light on firefly mysteries
...r words, are some male fireflies lying in order to find romance? "If female mate choice is adaptive, we would expect that the more attractive males would provide females with greater material benefits and/or genetic benefits," said Sara Lewis, associate professor of biology in the School of Arts & Sc...Fluorescing lab worms signal longer life spans
... "By finding them, we should ultimately be able to find what makes an animal robust to many different insults." Johnson authored a milestone paper in 1988 showing that mutating a single gene in roundworms could double their life span -- the first evidence that the lifespan of an animal could be increased...Wild grasses and man-made wheats advance research capabilities
...abiotic stresses," Rudd said. "I'm being forced to find broader gene pools to bring in the genetic variabi...can be looked at for other characteristics. "If we find something useful in the wild, we may make a synthetic hexaploid from it, or directly cross into whea...Can our genes tell the story of our divergence?
...mier open-access journal PLoS Biology. One way to find such genetic signatures is to search for genes tha... genes in humans to their equivalents in chimps to find positively selected genes in both species. Nielsen et al. identified many genes involved in sensory...Scientists discover that three molecules may be developed into new Alzheimer's drugs
...of California, Santa Barbara, headed the effort to find these molecules. The results of the study are publ...ng the disease process. The researchers set out to find a way to inhibit this enzyme, to keep it from putting any phosphate on tau. In the laboratory, they...Discoveries by UAB and Florida scientists may help transplanted organs survive longer
... list for a transplant, it would help immensely to find a way to reduce a patient's need for a second or third kidney." The helpful molecule, IL-10, has anti-inflammatory, immunosuppressive and other properties that help keep blood vessels healthy. Chronic vascular rejection, characterized by thickening ...Scientists at Galileo Pharmaceuticals confirm inflammatory response linked to glucose levels
...of California, Santa Barbara, headed the effort to find these molecules. The results of the study are publ...ng the disease process. The researchers set out to find a way to inhibit this enzyme, to keep it from putting any phosphate on tau. In the laboratory, they...Researchers feed tiny pills of RNA to planarians to identify genes essential for regeneration
...the possibility of systematic molecular studies to find the genetic cause of regenerative processes in animals." Silencing planarian genes may also help in studying human disease. Thirty-eight of the genes Sánchez Alvarado and his team silenced are related to human genes associated with diseases, such as...