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A new mechanism of regulating RNA degradation

...cognized for several years. "We were surprised to find that Staufen1 interacts with Upf1," she added. "This is a whole new function for Staufen1 that couldn't have been predicted from the studies in flies, even though a similar function may occur in flies." The team discovered that Staufen1 doesn't inte...

FDA Approves Human Hookworm Vaccine for Phase I Safety Trials

...cognized for several years. "We were surprised to find that Staufen1 interacts with Upf1," she added. "This is a whole new function for Staufen1 that couldn't have been predicted from the studies in flies, even though a similar function may occur in flies." The team discovered that Staufen1 doesn't inte...

Spleen may be source of versatile stem cells

...eported in their SAGE KE article, the MGH team did find that Hox11was produced in the spleens of adult mic...ne marrow in replenishing your blood supply. Wemay find that the spleen kicks in to help with many more biologicalemergencies. What has been considered a pr...

Yellowstone microbes fueled by hydrogen, according to U. of Colorado study

... living in thermal features. "Itwas a surprise to find hydrogen was the main energy source for microbesin...am used computer-generated thermodynamic models to find out ifhydrogen was indeed the principle source of energy. "You can smellsulfide in the air at Yellow...

It's not all genetic: Common epigenetic problem doubles cancer risk in mice

...n people, the current experiments were designed to find out whether the loss of imprinting is involved in cancer's development or just in its progression. "Most researchers, including me, expect epigenetic differences to influence progression -- whether a tumor would grow slowly or quickly, or whether it...

Novel technology detects human DNA mutations

...ugh the more than one billion base pairs of DNA to find a particular base pair of interest. Once that base pair is located, it is then necessary to determine if either of the bases is mutated (i.e., has SNPs). Nanosphere's technology can rapidly, easily, and accurately interrogate both bases in the pair t...

Priming embryonic stem cells to fulfill their promise

...g this combinatorialtechnique we were surprised to find many interesting interactions, andwe were able to ... there had been no practical wayfor researchers to find the optimal extracellular matrix needed to turnembryonic stem cells into cells with therapeutic pote...

Poor prenatal nutrition permanently damages function of insulin-producing cells in the pancreas

...uence, said Dr. Patti. "In our study, we needed to find out what was happening in these mice, before they got the problem." Their insulin levels provided a clue. In the prenatally undernourished mice, the insulin secretion stayed about the same, regardless of the glucose level in the bloodstream. "That s...

Emory Study Tests Bone Marrow Stem Cells to Improve Circulation in Legs

...ith peripheralvascular disease. Another goal is to find out whether or not increasingthe number of circula...ientsfor whom those treatments are not options. To find out more about thestudy and eligibility, call 404-712-0170....

Termites feed through good vibrations

... signals were broadcast. Scientists are hoping to find ways to interfere with the termites' ability to select wood in order to reduce the economic impact of termite damage. "There is a common perception that termites are voracious and indiscriminate eaters, consuming all the wood that they find," Dr Evan...

Genome of deadly amoeba shows surprising complexity, evidence of lateral gene transfer

...s at a time. Such information may help researchers find better means to harness the immune system to eradi... Petri says the genome data will help researchers find more about what makes some people innately resistant to infection by E. histolytica, and what acquir...

Timing is everything: First step in protein building revealed

...ic information in order to build a protein,only to find that it's not one step but two.In a series of experiments, the scientists found that when yeast'sprotein-building machinery recognizes the starting line for a gene'sinstructions, it first alters its structure and then releases a factorknown as eIF1, ...

Another Look Finds Promising Proteomics Test is Not Biologically Plausible

...y, whose quirks we don’t fully understand, you can find results that may be due to something other than bi...entity of which is often unknown). The goal is to find a pattern of peaks that will distinguish between patients with cancer and those who are cancer-free....

New species from old data

...y, whose quirks we don’t fully understand, you can find results that may be due to something other than bi...entity of which is often unknown). The goal is to find a pattern of peaks that will distinguish between patients with cancer and those who are cancer-free....

Cracking the olfactory code in bees

...y, whose quirks we don’t fully understand, you can find results that may be due to something other than bi...entity of which is often unknown). The goal is to find a pattern of peaks that will distinguish between patients with cancer and those who are cancer-free....

Signaling protein builds bigger, better bones in mice

...y, whose quirks we don’t fully understand, you can find results that may be due to something other than bi...entity of which is often unknown). The goal is to find a pattern of peaks that will distinguish between patients with cancer and those who are cancer-free....

New Technique for Tracking Gene Regulators

...technique gives us a new way to index the code, to find the placeswhere regulators act ?where the on/off switches are that determinewhich genes are at work in different types of cells under differentconditions,?he said.Previous, individual experiments have identified about 100 places whereCREB binds to DN...

Genome-wide mouse study yields link to human leukemia

...e range of methylated fragments is exactly what we find in human leukemia, too," says Caligiuri, "so that gives added merit to our mouse model as an investigative tool." Using data from the methylation studies, Caligiuri and Plass were able to identify a particular stretch of DNA, called Id4, as a tumor ...

Scientists seek answers on what activates deadly anthrax spores

...er and three other institutions are setting out to find what activates the spores in anthrax, the deadly bacterial infection that is back in the news. "A key aspect of anthrax spore biology concerns the germination process through which the dormant spore becomes a reproductive, disease-causing bacterium,...

Study finds more than one-third of human genome regulated by RNA

...echnology becomes moresophisticated, I think we'll find that even more genes are targeted bymicroRNAs," predicts Lewis.In addition, the team discovered some hints about how microRNAs findtheir targets.To produce a protein, the cell first makes a template for that proteinby constructing a molecule called m...

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