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Tag: "fighting" at biology news

Tuberculosis: The bacillus takes refuge in adipose cells

...oS ONE, sheds new light on possible strategies for fighting tuberculosis. Attempts to eradicate the bacillus entirely from infected individuals should take these newly identified reservoir cells into account. Mycobacterium tuberculosis, the bacillus responsible for tuberculosis can hide, in a dormant state,...

How blood flow dictates gene expression

...in blood vessel and muscle biology could help with fighting atherosclerosis. "We always knew that there had to be this line of communication from the vessel lining, or endothelium, to the smooth muscles, which never sees a blood cell," says senior author Mark Kahn, MD, Associate Professor of Medicine. "Tha...

Pure carbon nanotubes pass first in vivo test

...d. “Up to his very last day, he was simultaneously fighting his own battle with cancer and developing new ways to treat the disease that ultimately took his life. These new results are simply the first fruits of his final contributions in nanohealth research, and there are still more to come." ...

Scientist works to improve treatment for brain tumors

...ong survival in these patients ?that's what we are fighting for," he said. Currently, people with GBM have a median survival time of 12 to 14 months and a five-year survival rate of 1 percent to 5 percent. The drug's development was based on Debinski's finding that glioblastoma cells over-express large am...

Finding paves way for better treatment of autoimmune disease

...ory T cells when the body gets too many, say after fighting a big infection, and that it may not work well enough in people with autoimmune disease. ...

T cells activated to fight HIV basis for dendritic cell therapeutic vaccine

...nized to rally other cells of the immune system in fighting the virus unique to that individual. At the XVI International AIDS Conference (AIDS 2006), University of Pittsburgh researchers will describe one of the steps that is key to the approach's success ?modifying the dendritic cells in such a way that t...

Bones hold the key to blood renewal

...ed blood cells, possibly becoming immune cells for fighting infection or cells for blood clotting and healing after injury. They can even respond to calls for help from organs such as the liver, migrating through the bloodstream to assist in repairing damage. The inner walls of the bones are also sites of ...

Researchers map out networks that determine cell fate

...y active genes to carry out its particular role in fighting infection. A major scientific puzzle has been how and why immature hematopoietic stem cells initially express genes that are characteristic of both cell lineages. Until recently, however, there was no experimental system that researchers could man...

Researchers win money to develop breath test to detect breast cancer

One of the biggest problems in fighting breast cancer is the lack of inexpensive, early detection diagnostic tools. Researchers at the University of Michigan hope to change that by developing a device to test breath for the presence of metabolites associated with breast cancer. The team ...

Radiotherapy advance points way to noninvasive brain cancer treatment

...search into using a new radiotherapy technique for fighting GBM with the element gadolinium. The approach might some day lead to less invasive treatment and possibly a cure of this disease. "It's the most lethal cancer there is. The only good thing about it is that, if left untreated, death is relatively qui...

Mutation in blood stem cells provides clues to cancer development

...ine said, "We now appreciate that the challenge in fighting certain forms of blood cancer is partly due to a reservoir of leukemic stem cells that are resistant to current therapies. The discovery of the JAK2 mutation in stem cells in patients with PV is an important first step in developing treatments which...

Nano-particles effective in killing cancer with one-two punch of chemotherapeutics

...delivery system, and should prove a useful tool in fighting a number of diseases," said Dennis Discher, a professor in Penn's School of Engineering and Applied Science and a member of Penn's newly established Institute for Translational Medicine and Therapeutics. "Here we show that drug-delivering polymersom...

Loosen leash on cancer protein 'watchdog,' researchers say

...h teams had found that p53 was a good prospect for fighting cancer," she said. "With too little p53 protein, people and mice are more likely to develop cancer. But it's not a panacea. Embryonic mice with too much p53 in their systems don't survive gestation. Moreover, recent reports have suggested that high l...

A Jekyll and Hyde of cytokines: IL-25 both promotes and limits inflammatory diseases

...That is, a type 2 response that was once useful in fighting worm infections has now become a dangerous menace, causing inflammatory responses to commonly encountered environmental antigens. About 30 percent of Americans suffer from the negative affects of type 2 inflammation: asthma and allergies. These con...

Major WHO study concludes calcium supplements can reduce complications during pregnancy

...r scientists toward a completely novel approach to fighting HIV infections." In contrast to the colorful but static images on the covers of scientific journals, actual proteins are constantly quivering from the thermal motion of their atoms. Drug-binding sites that may be closed most of the time can be trans...

Computer simulation hints at new HIV drug target

...r scientists toward a completely novel approach to fighting HIV infections." In contrast to the colorful but static images on the covers of scientific journals, actual proteins are constantly quivering from the thermal motion of their atoms. Drug-binding sites that may be closed most of the time can be trans...

UCSD team unmasks family of immune system invaders

...ese findings may prove to be especially helpful in fighting bacterial disease in Third-World countries, in children and those with suppressed immune systems, such as HIV/AIDS patients. Contributors to the paper include Seema Mattoo, Feng Shao and Cheri S. Lazar, UCSD Departments of Pharmacology and Cellula...

New influenza vaccine takes weeks to mass produce

...essful purifications gives us a great advantage in fighting against a potential influenza pandemic, if it derived from any of these strains," says Wang. "Starting from a stocked recombinant baculovirus bank, a closely matched vaccine can be massively produced within 2 weeks." PSC has recently signed a Let...

Waking a sleeping virus

...terials to make new viruses. "A good strategy in fighting viruses is to block the activation of viral genes," says Patrice Morand, a physician at the University hospital and the IVMS. "The drugs we currently use against EBV work that way. The problem is that they only interrupt the late phase of the viral c...

Researchers map of genetic variations implicated in disease

...le, as might be expected from a region involved in fighting infection (as well as other functions). Over evolutionary time, the MHC has been driven to become the most variable region of our genome. The MHC Haplotype Project is studying in fine detail the sequence of eight of the most common human haplotypes,...

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