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Researchers learn how blood vessel cells cope with their pressure-packed job

...a much reduced degree," said Chien. Post-doctoral fellow Roland Kaunas, now an assistant professor of biomedical engineering at Texas A&M University, with the help of UCSD laboratory assistant Phu Nguyen, found that unstretched cells or cells that were stretched only 1 percent of their length contained...

Regenerating worms help elucidate stem cell biology

... was carried out by Helen Hay Whitney postdoctoral fellow Peter W. Reddien (now an Associate Member at the Whitehead Institute for Biomedical Research), and led by Howard Hughes Medical Institute investigator Alejandro Sánchez Alvarado. Salamanders, zebrafish, and other organisms are capable of regenerati...

Wolves' top-down effect

...ly repopulated adjacent areas. Hebblewhite and his fellow researchers were able to examine the effects of wolf exclusion on elk--wolves' preferred prey--on plants such as willow, which are favored by the ungulates, and on other species that depend on the willow habitat. Hebblewhite and his colleagues found...

UT Southwestern researchers unravel control of growing blood vessels

... for Basic Research in Pediatric Oncology. He and fellow researchers focused on a molecule called Foxo4, to see whether it might control myocardin; they found that it turns off myocardin, thus allowing smooth muscle cells to stop contracting and grow. The level of Foxo4, in turn, increases or decreases dep...

Sudden change in social status triggers genetic response in male fish, study finds

...around it," says Burmeister, a former postdoctoral fellow in the Fernald lab, now assistant professor of biology at the University of North Carolina-Chapel Hill. "The subordinate male is responding to the absence of another individual, so he has to have some kind of understanding of what their relationship ...

Normal chromosome ends elicit a limited DNA damage response

...ision, chromosome ends are exposed," says research fellow and first author Ramiro Verdun who emphasizes that, "it would be very unhealthy for the cell if it happened at any other time." In addition, Verdun and his colleagues found that several well-known members of the DNA damage response machinery ?recrui...

Prostate cancer uses Wnt signaling proteins to promote growth of bone tumors

...says Christopher L. Hall, Ph.D., a senior research fellow in urology at U-M. "But this is the first time Wnts have been shown to be involved in abnormal bone production in adult animals with prostate cancer." Hall is first author of a paper to be published in the Sept. 1 issue of Cancer Research, which pr...

Gene therapy for muscular dystrophy fixes frail muscle cells in animal model, Stanford study finds

... The gene therapy technique Rando and postdoctoral fellow Carmen Bertoni, PhD, used was developed by Michele Calos, PhD, associate professor of genetics. One of the main advantages of this method is that it could potentially provide a long-term fix for a variety of genetic diseases, including muscular dystr...

Why Christmas trees are not extinct

...al thesis by Jarmila Pitterman, now a postdoctoral fellow at the University of California, Berkeley. She and Sperry conducted the study with other University of Utah biologists: Uwe Hacke, a research assistant professor; lab technician James Wheeler, who has since left for graduate school at Harvard Univers...

Researchers know what you were about to say; fMRI used to detect memory storage and retrieval

...enced the event," said Sean Polyn, a post-doctoral fellow at the Computational Memory Lab in Penn's Department of Psychology. "It is all part of the brain's ability to cross-reference memories, pulling together separate pieces of information from an elaborate network of stored representations to recreate a...

Rutgers researchers scientifically link dancing ability to mate quality

...to desirability." Cronk and postdoctoral research fellow William Brown also examined results by the sex of the dancer. They found that symmetric males received better dance scores than symmetric females and that female evaluators rated symmetric men higher than male evaluators rated symmetric men. "In spe...

Penn study finds direct role for glial cells in brain cross-talk

...e lead author was Olivier Pascual, a post-doctoral fellow in Penn's Department of Neuroscience. Co-authors are Kristi Casper, Cathryn Kubera, Jing Zhang, Raquel Revilla-Sanchez, Jai-Yoon Sul and HajimeTakano. This study was funded by the National Institute of Neurological Disorders and Stroke and the Natio...

Brain activity related to processing faces is similar in people with, without autism

...es; and Dr. Gabriel Dichter, postdoctoral research fellow within UNC's Neurodevelopmental Disorders Research Center. The study involved functional magnetic resonance imaging, or fMRI. Unlike standard MRI scans that show anatomical structures in black and white, fMRI offers digitally enhanced color images o...

Neurons generated in the adult brain learn to respond to novel stimuli

...," says Sanjay Magavi, PhD, who led the study as a fellow in the laboratory of Jeffrey Macklis, MD, DHST, di...normally regenerate." Magavi is now a postdoctoral fellow at Massachusetts Institute of Technology. It had long been believed that neurons, the active cells...

Phenotype is influenced by nature, nurture and noise

...itri Bratsun and Dmitri Volfson, and post-doctoral fellow Lev. S. Tsimring modified the Gillespie algorithm, a well known computer model of cellular reactions, by factoring in intrinsic noise and delays. Using the modified Gillespie algorithm and sophisticated mathematical analyses of sets of biochemical re...

Worms know bad food when they smell it

...Cornelia I. Bargmann and Yun Zhang, a postdoctoral fellow in Bargmann's laboratory at The Rockefeller Univer... discern, Bargmann said. Hang Lu, a postdoctoral fellow in Bargmann's lab, used her engineering expertise to design a more complex maze for the worms to nav...

How Rickettsial pathogens break into cells

...Institute in Paris, together with her postdoctoral fellow Juan Martinez and collaborators in Paris and at Case Western Reserve University in Cleveland, Ohio, has identified the first receptor for a Rickettsial bacterium. Their findings will be reported in the December 16, 2005, issue of the journal Cell. R...

Young scientists turn to gel to ease side-effects of cancer treatment

... Paul Watson, together with post-doctoral research fellow Mark Godber, have developed the gel which will help doctors to target cancer tumours more efficiently. Now, the group has secured £30,000 under the Bioscience Yorkshire Enterprise Fellowship scheme to commercialise their idea. Their product, a for...

Researchers discover new form of cancer gene regulation

...n of protein function. Olga Lakiza, postdoctoral fellow in pediatrics at the Feinberg School, was the first author on the article. Iannaccone's other co-researchers on this study included David O. Walterhouse, associate professor of pediatrics, Feinberg School and Children's Memorial Research Center, and ...

Technique offers new view of dynamic biological landscape

... led by Weissman, Maya Schuldiner, a post-doctoral fellow working in his lab, and Nevan Krogan at the University of Toronto, described initial studies of E-MAP in yeast in the November 4, 2005, issue of the journal Cell. Weissman and his colleagues at UCSF collaborated on the studies with researchers at t...

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