Sugar helps control cell division
... first author, Chad Slawson, Ph.D., a postdoctoral fellow in biological chemistry in Johns Hopkins' Institute for Basic Biomedical Sciences. "In contrast, our experiments show that by increasing or decreasing the amount of sugar attached to proteins, the cell cycle is disrupted and isn't salvageable unless ...No small feat: First ever gene therapy success for muscular dystrophy achieved
... the study's first author and a research associate fellow in Dr. Xiao's lab. Future directions for research include finding a way to engineer the laminin alpha-2 gene. For this study, the authors chose to use the mini-agrin gene because researchers from the University of Basel, Switzerland, had already dem...UCSD discovery may provide novel method to generate medically useful proteins
...ease," said Stephen McMahon, a former postdoctoral fellow in Ghosh's lab who conducted much of the research. "This idea has already been picked up by the biotech industry." The function of the massively variable phage protein is to tether the phage to the bacteria they infect. The phage "predator" protei...Evolution of life on Earth may hold key to finding life in outer space
...nors and awards for his research. He is an elected fellow of the American Academy of Microbiology, the American Association for the Advancement of Science and the American Institute of Medical and Biological Engineering. As a postdoctoral researcher with Carl Woese at the University of Illinois, Fox was inv...Computers close in on protein structure prediction
..." said first author Philip Bradley, a postdoctoral fellow in Baker's lab. "It is a real step forward to achieve structures that are in some way comparable to what you can get by experiments." The encouraging results come from a refinement of a sophisticated computer modeling program called Rosetta, first d...Virus uses tiny RNA to evade the immune system
...f course be pirated by a virus," said postdoctoral fellow Adam Grundhoff, co-first author of the paper. Tho...-first author Christopher Sullivan, a postdoctoral fellow in Ganem's lab, started their search for viral microRNAs with a small virus, known as SV40, in the b...A radical solution for environmental pollution
... E. Neil Marsh, who did the work with postdoctoral fellow Chunhua Qiao. Free radicals---highly reactive chemical species that have been implicated in aging, diseases such as Alzheimer's and cancer, and even destruction of the ozone layer---aren't all bad, Marsh said. Many essential chemical reactions occur...Study: Plants use dual defense system to fight pathogens
...d graduate student Luis da Cunha and post-doctoral fellow Aidan McFall, both in the department of horticulture and crop science; Youssef Belkhadir and Jeffrey Dangl, both with the department of biology at the University of North Carolina, Chapel Hill; and Sruti DebRoy, formerly of the U.S. Department of Ene...Brain networks change according to cognitive task
...ork during Rhyming and Spelling." A post-doctoral fellow in the department of communication sciences and disorders, Bitan worked with Associate Professor James Booth of the same department and M-Marsel Mesulam, director of the Cognitive Neurology and Alzheimer's Disease Center in Northwestern's Feinberg Sc...UW-Madison scientists zero in on drugs' sweet spots
...rmer UW-Madison graduate student and post-doctoral fellow and now a chemistry professor at Seattle University; Noel R. Peters, and Professor F. Michael Hoffmann of the UW-Madison Comprehensive Cancer Center's Small Molecule Screening Facility; and Ilia A. Guzei, director of crystallography in the UW-Madison...North & South American researchers find architectural abnormalities in T. cruzi ribosome
...ified ribosomes from T. cruzi. There, postdoctoral fellow Haixiao Gao led the experiment, using a technique that works on a principle similar to a medical CAT scan. First, the researchers freeze an ultrathin layer of buffer with purified ribosomes so quickly that the water has no chance to crystallize and ...Most embryos produced during IVF do not result in live births
...etween these two needs." Patrizio said he and his fellow physicians strive to better identify the embryos with the most potential. But addressing the growing pressure to transfer fewer embryos to reduce multiple births is a difficult task unless they can come up with a method in the lab to identify the bes...NIEHS launches website with information for assessing environmental hazards from Hurricane Katrina
...ite is one vehicle that NIEHS is using to help our fellow citizens." Information in the GIS, such as the demographics of populations before Katrina will be helpful as health officials treat displaced citizens who may have been previously exposed to toxicants. Subsequent phases will provide more in-depth in...FDA approves child-friendly AIDS medicine
...ite is one vehicle that NIEHS is using to help our fellow citizens." Information in the GIS, such as the demographics of populations before Katrina will be helpful as health officials treat displaced citizens who may have been previously exposed to toxicants. Subsequent phases will provide more in-depth in...Drug resistant avian influenza viruses more common in Southeast Asia than North America
..." said Natalia A. Ilyushina, Ph.D., a postdoctoral fellow in the Infectious Diseases Department at St. Jude. First author of the Virology paper, Ilyushina did much of the work on this project. The St. Jude researchers analyzed the M2 gene sequences from 60 influenza viruses isolated in Southeast Asia and 7...U-M scientists discover identifying markers for primitive blood-forming stem cells
... Toshide Iwashita, M.D., Ph.D., a former research fellow in Morrison's laboratory and co-first author on the study, was responsible for the tissue section analysis. Cox Terhorst, Ph.D, from the Beth Israel Deaconess Medical Center and Harvard Medical School also collaborated in the research. Morrison's re...Color perception is not in the eye of the beholder: It's in the brain
... a related experiment, Williams and a postdoctoral fellow Yasuki Yamauchi, working with other collaborators from the Medical College of Wisconsin, gave several people colored contacts to wear for four hours a day. While wearing the contacts, people tended to eventually feel as if they were not wearing the c...MicroRNAs have shaped the evolution of the majority of mammalian genes
...onary level," says Andrew Grimson, a post-doctoral fellow in Bartel's lab. In order to make a protein, a gene codes for a specific molecule called messenger RNA, or mRNA. Each mRNA molecule contains a blueprint for making a protein. A microRNA can bind to a short sequence on a targeted mRNA and suppress p...Human cerebellum and cortex age in very different ways
... and cerebellum," says Joshua B. Plotkin, a junior fellow in the Harvard Society of Fellows. "The fact that gene activity levels in the cerebellum remain more stable as a person ages suggests that this region of the brain experiences less oxidative stress and damage as part of normal aging." "Much remains ...Scientists develop nanotech-laser treatment that kills cancer cells without harming healthy tissue
...thors are Michael O'Connell, a former postdoctoral fellow in the Department of Chemistry, and graduate student Jeffrey A. Wisdom in the Department of Applied Physics. The study was partly supported by the National Science Foundation Center on Polymer Interfaces and Macromolecular Assemblies, a research par...