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Tag: "failure" at biology news

Malaria may fuel spread of HIV in sub-Saharan Africa

...s," he said. "The global public-health system's failure to deal with the challenge of HIV/AIDS contributes directly to its failure to tackle other public-health challenges such as malaria and tuberculosis," Abu-Raddad said. "As lon...

Studies find general mechanism of cellular aging

...ng-related diseases such as diabetes result from a failure of cell growth, said Dr. Norman E. Sharpless, co-author on the three studies and an assistant professor of medicine and genetics at the UNC School of Medicine. "The studies indicate that certain stem cells lose their ability to divide and replace the...

'GreeneChip' -- New diagnostic tool that rapidly and accurately identifies multiple pathogens

...overnmental organization had acute fever and liver failure that culminated in death within one week. PCR ass... For example, one of the children died of cardiac failure caused by plasmodium falciparum (malaria). Therapeutic options for treatment of VHF are limited; ho...

Bones at the nanoscale

...his effect in biomaterials ?small particles resist failure better. Scientists carried out experiments on ID2 beamline at the ESRF. They tracked the molecular and supramolecular rearrangements in bone while they applied stress using the techniques of X-ray scattering and diffraction in real time. The h...

Mutant gene causes severe kidney disease in infants

...vere, early-onset form of kidney disease and renal failure in children: recessive mutations in a gene called phospholipase C epsilon or PLCE1. Identifying the mutant gene is important to scientists because PLCE1 affects the development of podocytes ?specialized cells that play a vital role in the kidney's a...

New study aims to stop sepsis in its tracks

... and heart rate. It can lead to the malfunction or failure of several major organs. "The goal of this project is to speed recovery, increase survival rates, and improve the long-term quality of life for those who have had sepsis," said NIGMS Director Jeremy M. Berg, Ph.D. One of the major challenges is t...

Mechanical 'artificial hearts' can remove need for heart transplant by returning heart to normal

... currently used in patients with very severe heart failure whilst they await transplantation. The new study, ...dy also highlights the fact that 'end stage' heart failure can be reversed and that the heart has the capacity to regenerate itself. It therefore stimulates th...

Minuscule molecules pack a powerful punch

...ive miR-155 are altered activation of other genes, failure to mount an effective immune response, susceptibility to autoimmunity and susceptibility to infection. "This dramatic finding reflects a large amount of work by collaborating groups," said Professor Allan Bradley, Director of the Wellcome Trust Sa...

Moonlighting enzyme linked to neurodegenerative disease

...ients become wheelchair-bound and succumb to heart failure later in life. There is no cure at this time, but Mayo Clinic researchers have identified mutations in an enzyme that may contribute to the disease. "Children and teens want to be on top of the world and having a disease like this is devastating for...

Twenty of world's 162 grouper species threatened with extinction

...of threatened species also reflects the widespread failure to successfully manage fisheries associated with coral reefs. Groupers are among the oldest fish on coral reefs, with some species reaching more than 50 years old. Several species only reach reproductive maturity later in life, making them particu...

Biologists produce global map of plant biodiversity

..., but important way so that such a fatal potential failure can be averted." ...

Discovery of an HIV inhibitor in human blood points to new drug class

...red from the blood of patients with chronic kidney failure during dialysis, in search of those with anti-HIV activity. After sorting the more than one million blood peptides into 300 fractions, they focused on one that blocked HIV without toxic effects on cells. Further examination revealed VIRIP as the a...

FSU researchers determine a critical factor in workings of proteins

...al for the creation of proper cell structures. The failure of the protein to associate quickly, then, is the root cause of the condition." In their Structure paper, Zhou and graduate student Razmi Alsallaq put forth a new theory that has been proven to accurately predict the association rate for proteins ...

Gene that makes people 'early to bed and early to rise' demystified

... modified by another enzyme that controls it. That failure leads to a reduction in the number of copies of the Per2 "message," and the characteristic shifted sleep pattern. Eventually, such insight into the factors influencing people's so-called circadian, or daily, rhythm might lead to therapies that cou...

Protein overexpression at heart of heart failure

Chronic heart failure resulting from dilated cardiomyopathy is rapidly e... L-type channels (L-VDCC), but their role in heart failure is still controversial. Electrophysiological studies on individual L-VDCCs from failing human heart ...

Putting an old drug to a new use

...ron in various tissues, where it can lead to organ failure and even death if not treated before irreversible ...er repeated blood transfusions and can cause organ failure over time. Günter Weiss, a clinician from the Innsbruck Medical University, and his collaborators fr...

UW launches study testing adult stem cells for heart damage repair

...stable angina, heart attacks and progressive heart failure when adequate blood flow is not restored. CMI deve...ading to significant disability, progressive heart failure and often death. ...

Indicators for risk of heart disease are higher in passive smokers

... or younger with no history of heart attack, heart failure or stroke also made lifwttle difference in the association. Dr Venn said: "Our study shows that very low levels of exposure to second-hand smoke may be associated with appreciable increases in cardiovascular risk. While the cotinine levels were on...

Study shows hope for early diagnosis of Alzheimer's

...an evaluation until a considerable degree of brain failure has occurred. The advantage of using a modified EEG to detect these early changes is that it is non-invasive, simple to do, can be repeated when necessary and can be done in a physician’s office. This makes it an ideal method to screen elderly indivi...

Trusting your instincts leads you to the right answer

...distinctive enough in the 'eyes' of the conscious, failure of identification can occur." ...

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