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Tag: "failure" at biology news

Primates on the brink

...nimal trade as the primary threats, and warns that failure to respond will bring the first primate extinctions in more than a century. The golden-headed langur of Vietnam and China's Hainan gibbon number only in the dozens. The Horton Plains slender loris of Sri Lanka has been sighted just four times since ...

B cells are required for development of epithelial cancer associated with chronic inflammation

...d B lymphocytes in this model system resulted in a failure to recruit innate white blood cells to premalignant skin and an absence of chronic inflammation. As a consequence, parameters of early cancer development were attenuated, and cancer incidence was significantly reduced. The researchers went on to show...

Study shows humans have ability to track odors, much like bloodhounds

...ents, according to Sobel. One explanation for this failure was that von Bekesy used chemicals that stimulate not only the olfactory nerve in the nose, but also a nasal sensory nerve, the trigeminal nerve. Most odors stimulate both, and some, like onions and ammonia, are stinging enough to bring tears to the ...

Scientists succeed in cloning human embryos from eggs matured in the lab

...rly embryos developed to the blastocyst stage, and failure to do so could reveal some problems in gene activation, especially in cloned embryos. So, first we have to understand how to get cloned blastocysts of good quality from in vitro matured oocytes. This will be difficult because it is well known that em...

Invitrogen Launches i-Path -- A Unique Systems Biology Platform at BIO 2005

...rly embryos developed to the blastocyst stage, and failure to do so could reveal some problems in gene activation, especially in cloned embryos. So, first we have to understand how to get cloned blastocysts of good quality from in vitro matured oocytes. This will be difficult because it is well known that em...

Insects develop resistance to engineered crops

... extensive use, there have been no reports of crop failure or insect resistance in the field to genetically modified Bt crops, Shelton said. Still, several insects have developed resistance to Bt toxins in the lab, and recently, cabbage loopers (a moth whose larvae feed on plants in the cabbage family) have ...

Hepatitis C responds best to combo of ribavirin and interferon, study concludes

...virus replication. The researchers were measuring failure to respond adequately to treatment under each course of treatment. In tests for presence of the virus among those who had never been treated for the disease, 83 percent of those on interferon did not respond after six months, compared to 58 percent ...

Insulin pulses keep the liver lean

...heir breakdown and release into the bloodstream. A failure to make or respond to insulin in people with diabetes causes blood sugar levels to rise. The current study uncovered a new mechanism whereby acute insulin pulses limit fat synthesis in the liver. This protective mechanism fails in obese mice and mic...

Scientists show that tick-borne flaviviruses use a novel mechanism to evade host defenses

...the first definitive study that dissects where the failure occurs in the signaling pathway, and then identifies some of the interacting partners in the cell and virus." Prior to this work, Dr. Bloom says, scientists knew only that NS5 helped tick-borne flaviviruses replicate. RML's Sonja Best, Ph.D., who sp...

Survival of heart patients on beta-blockers varies greatly with genetic variation

... now a member of the cardiology staff in the heart failure and cardiac transplant section at Henry Ford Hospi... hypertensive patients and heart function in heart failure patients. "But this is the first time that anyone has shown that these genetic variations affect s...

Chemical 'band-aid' prevents heart failure in mice with muscular dystrophy

...to cardiac muscle cell membranes and prevent heart failure in mice with the genetic mutation that causes Duch...nne muscular dystrophy die in their 20s from heart failure caused by cardiomyopathy, a gradual weakening of the heart muscle. Heart failure is the second leadi...

Researchers create infectious hepatitis C virus in a test tube

...infected by HCVcc unless they express CD81. Liver failure due to hepatitis C is the leading cause of liver transplants in the United States, and about 25 percent of liver cancer cases in the country are associated with HCV. Although about 85 percent of those who are infected develop chronic infection, the v...

Hopkins scientists uncover 'tags' that force proteins to cell surface

...ting CF. Although many scientists would say that failure to get these proteins to the cell surface means the proteins weren't assembled properly in the cell, Li says that how and where proteins are made has a lot to do with the difficulties researchers have had. For one, proteins are made deep inside the...

Researchers identify genes associated with lung transplant rejection

...ronchitis (OB), the most common cause of long-term failure of transplanted lungs. The researchers hope their results will lead to an earlier, more sensitive, and more accurate standard test for chronic lung rejection, as well as greater understanding of the rejection process. The study is being published i...

Newfound roadblock to interferon effectiveness against malignant melanoma

...of the disease. The findings explain the frequent failure of interferon therapies and thus further our understanding of melanoma in its late, and most aggressive, stage. In the future, a routine analysis of the STAT5 status in melanoma patients might help to improve and personalize therapies. ...

Life-extending protein keeps blood sugar in check

...ose from the bloodstream and burn it for energy. A failure to make or respond to insulin in people with diabetes causes blood sugar levels to rise. The researchers found that Sirt1 is present in pancreas cells that secrete insulin hormone. Mice genetically modified to have an excess of Sirt1 in b cells of t...

Newly Discovered Role for Heart Response Enzyme May Yield Better Heart Failure Therapy

...ction in response to exercise or stress. In heart failure patients, chronic stress leads to an excess of adrenaline, over-stimulating beta-adrenergic receptors, a process that results in receptor desensitization and loss, Rockman said. Earlier work by Rockman's team identified PI(3)K as being required for ...

Sea Ice May Be on Increase in the Antarctic

...ose from the bloodstream and burn it for energy. A failure to make or respond to insulin in people with diabetes causes blood sugar levels to rise. The researchers found that Sirt1 is present in pancreas cells that secrete insulin hormone. Mice genetically modified to have an excess of Sirt1 in b cells of t...

Time and money make a difference in endangered species recovery

...ies Act in judging whether the law is a success or failure in recovering biodiversity. This issue has become a major focus of political battles over this controversial environmental law. ...

Stem cells bring fast direct improvement, without differentiation, in acute renal failure

...that patients with ARF often simultaneously suffer failure of other major organ systems. The most serious fo...al stem cells protect against ischemic acute renal failure through differentiation-independent mechanisms," appears in the American Journal of Physiology-Renal...

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