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Tag: "factor" at biology news

Skin disease common among Hispanic farmworkers in North Carolina, research shows

... problem, yet exposure to sunlight is a major risk factor for the disease. The interviews also revealed that a common belief among workers is that each individual's personal susceptibility determines whether they will be affected by a condition. "Farmworkers do not acknowledge several skin diseases that sh...

Marine mammals are on the frontline of failing ocean health

...cific genetic traits and a herpes virus, are a key factor in causing the cancer. "We see the herpes virus in sea lions without cancer, so the virus alone isn't enough to cause cancer in sea lions, which is why we think organochlorines (a class of POPs) play a role either directly in the urogenital tract ...

World faces challenge as life expectancies lengthen, scientist says

...g." However, an increase in citizenry is only one factor in determining a nation's socioeconomic health, he...derly, who are frequently retired or disabled. To factor in this phenomenon, Tuljapurkar examined the effects of anti-aging technologies on the national depe...

A surprising pair of proteins help make healthy eggs

...ence describing the essential role a transcription factor called TAF4b plays in the fertility of female mice. Without this protein, egg-producing ovarian follicles didn't develop properly. The result: infertile mice. The new research underscores TAF4b's central role in normal reproduction. The Brown and Be...

How the brain learns to become addicted

...oup that another molecule, corticotropin releasing factor (CRF), acts similarly. Such adaptations are believed to create a need that is far more compelling than the simple memory of drug-induced pleasure and represent a "rewiring" of the brain into an addictive state. In a preview article on the paper in ...

Powerful technique for multiplying adult stem cells may aid therapies

...al Blood how one of these genes codes for a growth factor protein called IGF-2. When Zhang purified IGF-2 an...mber. Zhang then discovered that two more growth factor proteins, Angiopoietin-like 2 and ?, abbreviated as angpt12 and angpt13, were also abundantly expres...

Testes to incubate stem cells

...s a similar goal. Bizarrely, a brain cell growth factor also has a powerful influence on spermatogonial stem cells. Glial cell derived neurotrophic factor (GDNF) is also involved in spermatogenesis: levels are high during the neonatal period and drop in a...

Warming trend may contribute to malaria's rise

... not mean that temperature is the only or the main factor driving the increase in malaria, but that it is on...ons, any increase in abundance can be an important factor in transmission of the disease." In the current study, the researchers looked only at the link bet...

UCI researchers discover key factor for survival of human embryonic stem cells

...trophin growth factors ?brain derived neurotrophic factor (BDNF), neurotrophin 3 (NT-3), and neurotrophin 4 (NT-4) ?were added to hES cells in culture, the cells' survival increased 36-fold. "Keeping hES cells alive as single cells has been extremely difficult," Donovan said. "This fact has kept us from ...

Tiny RNA molecules fine-tune the brain's synapses

...nes to grow. When neurons were exposed to a growth factor known as brain-derived neurotrophic factor (BDNF), this inhibition was overcome and Limk1 became active again, enhancing spine growth. Greenbe...

UC San Diego partners with Venter Institute to build marine microbial genomics cyberinfrastructure

...er for science at the Moore Foundation. "The major factor limiting its further progress has been the management of the very large quantities of data. We are delighted to be able to support the development of this community resource at one of the world's premier sites for high-speed networking and high-perfo...

Botox could help target resistant tumors for treatment

...f resistance to radiotherapy, and is a determining factor in the poor prognosis of tumors to cytotoxic treatments," said Gallez. "Botulinum toxin could lead to inhibition of contractions of tumor vessels, improve tumor perfusion and oxygenation, and enhance the response of tumors to radio- and chemotherapy....

Researchers discover a new genetic cause of Alzheimer's disease

... of amyloid protein in brain cells is a major risk factor for Alzheimer's disease. Amyloid protein has alrea...he brain tissue of Alzheimer patients is a central factor in the search for a therapy for Alzheimer's disease. A lot or not much of the amyloid precursor pro...

The urban evolution lab

... of amyloid protein in brain cells is a major risk factor for Alzheimer's disease. Amyloid protein has alrea...he brain tissue of Alzheimer patients is a central factor in the search for a therapy for Alzheimer's disease. A lot or not much of the amyloid precursor pro...

Absence of critical protein linked to infertility

...emy of Sciences -- indicate that the transcription factor protein C/EBPb must be present in the uterus for pregnancy to occur. The study appears online this week at the PNAS Web site. Without it, they say, an embryo cannot survive in uterine tissue or attach to a mother's blood supply. Other genes also pla...

Tool developed to silence genes in specific tissues using RNAi

...coding a regulatory protein called a transcription factor that controls the formation of adherens junctions,... the discovery that WT1 is the first transcription factor shown to regulate the formations of these junctions, Wilkinson says. "It is a transcription factor t...

Cuttlefish masters of disguise despite colorblindness

...ger and her colleagues suspect might be a critical factor in uncovering what determines camouflage patterning in cuttlefish. Despite these results, the vexing question of how cuttlefish master the task of camouflage in low-contrast, color-rich environments such as those found at shallow depths of water, re...

NHGRI announces new sequencing targets

... base pairs is roughly the size of a transcription factor binding site: a small DNA sequence occurring near a gene that is involved in switching the gene on or off. Sequencing efforts will be carried out by the NHGRI-supported, Large-Scale Sequencing Research Network, which consists of five centers: Agenco...

Basic research leads to a novel cancer therapy

...re and function of a receptor for epidermal growth factor (EGF). Since then, tyrosine kinases and various gr...res in size can create vascular endothelial growth factor (VEGF), which triggers blood vessel development. Ullrich found some of the most important evidence ...

Protein finding could lead to treatment for inflammatory diseases

...appaB" she said. NF-kB is a cellular transcription factor that activates the expression of genes involved in inflammation. Shisler's lab was interested in determining whether MC160 also acted on NF-kB. In their study -- funded by the National Institutes of Health -- Shisler and Daniel Brian Nichols, a doc...

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