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Tag: "factor" at biology news

No link found between caffeine intake and development of hypertension in women

...ation in the article. Hypertension is a major risk factor for coronary heart disease, stroke, and congestive heart failure. Therefore, even small reductions in the prevalence of hypertension could have a potentially large public health and financial impact. Several previous studies have indicated a possibl...

Group proves it's possible to grow new lung alveoli by growing new blood vessels

...and that angiopoeitin-1, another angiogenic growth factor is crucial for blood vessel maturation, the team a...s of lung cells. Once inside the cells, the growth factor proteins went to work doing the job they were programmed to do. The results were striking: In micro...

Forgotten by evolution?

... On one hand, the stem cells could be missing some factor which is absolutely necessary for the complete differentiation into specialised cells and tissue. On the other hand, it could be the case that at least some of the known adult stem cell types are "only" the rudiments of earlier embryonal differentiat...

NASA's AURA satellite peers into Earth's ozone hole

... the atmosphere are decreasing. Another important factor in how much ozone is destroyed each year is the temperature of the air high in the atmosphere. As with temperatures on the ground, some years are colder than others. When it's colder in the stratosphere, more ozone is destroyed. The 2005 ozone hole w...

Preclinical study of a new brain tumor therapy

...e detection of molecules known as epidermal growth factor receptors (EGFR). The glioblastoma cells overexpress EGFR (that is, in comparison with normal brain cells, they have many more of these molecules on their surface). The scientists then selected a type of genetic material (a nucleic acid) associated w...

MicroRNA may have fail-safe role in limb development

...ription factor. "It's turning off a transcription factor in the hindlimb that is important for forelimb development," Harfe said. "But it still doesn't explain why a hindlimb is a hindlimb and a forelimb is a forelimb." The next step in the research is to observe limb development in mice engineered to not...

UCSD study finds anthrax toxins also harmful to fruit flies

...umans. Guichard and her co-authors applied lethal factor toxin to fruit fly embryos and larvae and observed... anticipate that toxins such as the anthrax lethal factor toxin that have multiple host target proteins may be used to simultaneously reduce or eliminate the ...

Depression model leaves mice with molecular scar

...ression of the gene for brain derived neurotrophic factor (BDNF) to normal levels and reversed the social withdrawal behavior. BDNF in the hippocampus has been linked to memory, learning and depression, but Nestler said social defeat stress probably similarly affects other genes there as well. The research...

Stem cell mobilization therapy appears to be ineffective in repairing damage caused by heart attack

...ll based therapies. Granulocyte colony-stimulating factor (G-CSF, a growth-factor protein) induces mobilization of bone marrow stem cells, according to background information in the article. Dietlind Zohlnhöfer, M.D., of the Technische Universität, Munich, Germany, and colleagues conducted a randomized, do...

Stem cells from muscles can repair cartilage

...hich they grew. The addition of transforming grown factor â1 (TGFâ1) to MDSC-B4 did not enhance chondrogenic differentiation. The authors conclude that skeletal muscle is a promising source of cells that can differentiate into cartilage-producing cells. "The MDSCs used here served as good carriers of a the...

Source of crucial immune cell in the skin discovered

...so found that a protein, called colony stimulating factor receptor (Csf-1) is necessary for the transformation of Gr-1 cells into Langerhans cells. The researchers state that discovery of how Langerhans cells are replaced "should contribute to ongoing efforts to engineer immune responses in vaccine design ...

Free HIV tests cheaper than charging when goal is preventing AIDS

...ges that the cost of free testing is a significant factor for organizations with limited resources. "Cost is probably the biggest barrier, but if the goal is to prevent HIV infection, free HIV testing and counseling provides outstanding bang for your buck," he said. "Right now there is a lot of emphasis o...

Ancient DNA helps UF researchers unearth potential hemophilia therapy

...om hemophilia stems from how much of this protein, factor VIII, is missing," said Bradley Fletcher, M.D., Ph...ells are potentially a very important cell to make factor VIII," said Katherine P. Ponder, M.D., an associate professor of medicine and a hemophilia researche...

Environmental tobacco smoke linked to behavior problems in children and pre-teens

...tobacco smoke is increasingly recognized as a risk factor for child behavior problems." In the United States, about 25 percent of children are exposed to environmental tobacco smoke in their own homes, yet more than 50 percent of children have detectable levels of cotinine in their blood, according to Dr. ...

Swiss researchers develop all-in-one remote control gene expression tool

...ed in the lentivirus the expression of this growth factor can now be turned off when the desired effect is achieved, thus preventing unharnessed growth ?otherwise known as cancer. "It's an extremely polymorphic tool, useful in testing therapies and in preclinical studies," says Trono. "Using it we can cont...

Whole-genome study at Johns Hopkins reveals a new gene associated with abnormal heart rhythm

...ars to influence significantly one particular risk factor - the so-called QT interval length - for sudden ca...ving a too long or too short QT interval is a risk factor for sudden cardiac death," says the study's co-first author, Dan Arking, Ph.D., an instructor in the...

Ocean 'dead zones' trigger sex changes in fish, posing extinction threat

..."Reproductive success is the single most important factor in the sustainability of species," Dr. Wu says. "In many places, the areas affected by hypoxia are usually larger than the spawning and nursery grounds of fish. Even though some tolerant species can survive in hypoxic zones, they may not be able to m...

Alcoholism, smoking and genetics among Plains American Indians

...lleagues also found that the Val allele was a risk factor for smoking, but only in women. For the current study, researchers recruited 342 (201 women, 141 men) community-based Plains American Indians, establishing their lifetime drinking and smoking histories. Additionally, five COMT loci ?including Val15...

Sustainable farm practices improve Third World food production

...farming practices require less water, an important factor given that predictions suggest by 2025 most developing countries will face physical or economic water shortages, Pretty says. About 800 million people in the developing world are short of food and agriculturally driven environmental damage threaten...

Horseshoe crab decline threatens shorebird species

...mber of horseshoe crab eggs was the most important factor determining the use of the beaches by red knots. The availability of horseshoe crab eggs was even more influential than the presence of human disturbance, predator occupation, and availability of other types of food," says Karpanty, a post-doc in the...

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