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Tag: "factor" at biology news

WHO suspends Marburg work, appeals for new funds

.... In African countries, the single most important factor in controlling viral haemorrhagic fevers is the engagement of affected communities as partners in control. To achieve this engagement, local belief systems about the causes of disease and traditional rituals for mourning the dead must be respected. W...

Primates on the brink

... collection of fuel wood continues to be the major factor in the declining number of primates, according to the report. Hunting for subsistence and commercial purposes also is a major and insidious threat, especially in Africa and Asia. Live capture for the pet trade also poses a serious threat, particularl...

Embryonic Stem Cells Treated With Growth Factor Reverse Hemophilia In Mice: UNC Researchers

...ryonic stem cells treated in culture with a growth factor and then injected into the liver reverse a form of...netically altered mice lack the clotting substance factor IX, which in humans results in the hereditary bleeding disorder known as hemophilia B. This disease,...

Research may provide new link between soft drinks and weight gain

...ata, the researchers now also believe that another factor contributing to the increased fat storage is that the liver metabolizes fructose differently than it does other carbohydrates. "Similar to dietary fat, fructose doesn't appear to fully trigger the hormonal systems involved in the long-term control o...

The first impact factor for PLoS Biology ?13.9

...has been assessed by Thomson ISI to have an impact factor of 13.9*, which places PLoS Biology among the most... the scientific and medical literature. An impact factor of 13.9 places PLoS Biology above such established journals as EMBO Journal, Current Biology, and th...

Vitamin A's paradoxical role in influencing symmetry during embryonic development revealed

...luence pattern formation -- Wnt, fibroblast growth factor and Notch -- and found that none of them was responsible for coordinating the antero-posterior and left-right axes. However, blocking the retinoic acid pathway generated an uneven distribution of tissue on the right and left halves of the body. That ...

Critical step traced in anthrax infection

...e. The pore permits the other two proteins, lethal factor (LF) and edema factor (EF), to enter the cell interior, where the factors interfere with metabolic processes, leading to d...

Studies reveal how plague disables immune system, and how to exploit the process to make a vaccine

...se. LcrV also prevents secretion of tumor necrosis factor (TNF), which causes inflammation. "LcrV is secreted in massive amounts via the type-III pathway during an infection," Schneewind said. "Without it, the bacteria are relatively harmless." Consequently, researchers have tried to use LcrV alone as a v...

Open Access journals get impressive impact factors

...tors this year. BMC Bioinformatics, with an impact factor of 5.42, has reinforced its reputation as one of t... bioinformatics journal, and already has an impact factor comparable to that of Bioinformatics (5.74), the most established journal in the field, which has be...

'Bionic' arm gives amputee sense of touch

...tors this year. BMC Bioinformatics, with an impact factor of 5.42, has reinforced its reputation as one of t... bioinformatics journal, and already has an impact factor comparable to that of Bioinformatics (5.74), the most established journal in the field, which has be...

Recombinant DNA technology may enable oral, rather than injectable, delivery of protein drugs

...based drugs such as granulocyte colony-stimulating factor (G-CSF) to create a new oral compound that is capa...as isolating the genetic code for G-CSF, a protein factor that stimulates white blood cell production in the body. G-CSF is used to make Neupogen(r) and Neula...

Combination therapy leads to partial recovery from spinal cord injury in rats

...eurotrophin 3 (NT3) and brain-derived neurotrophic factor (BDNF). Both NT3 and BDNF help myelin-producing cells (oligodendrocytes) develop and survive. Dr. Whittemore and his colleagues injected the treated precursor cells into the spinal cords of rats with a type of spinal injury called a contusion, which...

Study: Well-known protein helps stem cells become secretory cells

...n the salivary gland. "CrebA is the more immediate factor involved in keeping secretory genes expressed at h...ur findings suggest that this single transcription factor directly determines the amount of secretory activity in a given cell type," said Andrew. ...

Bioinformatics reveals new gene regulation system

...mparative genomics to identify a new transcription factor system in bacteria that represses expression of ge...al sequence, but also the regulatory transcription factor that bound it, the repressor nature of the signal, and other genes also regulated by this system. "...

Modified collagen could yield important medical applications

.... Still other medical uses are possible. A growth factor joined to collagen could encourage new cells to multiply. An antibiotic attached to collagen could help a collagen-based bandage fight infections over a long period of time. Modified collagen could also release helpful medications while serving as a ...

Unusual antibiotics show promise against deadly 'superbugs'

.... Still other medical uses are possible. A growth factor joined to collagen could encourage new cells to multiply. An antibiotic attached to collagen could help a collagen-based bandage fight infections over a long period of time. Modified collagen could also release helpful medications while serving as a ...

Arthritis: What Wnt wrong?

...which Wnt-7b would be an important pathobiological factor in rheumatoid arthritis," added Nakamura. Future studies will investigate the role of Wnt and its signaling partners in arthritic joint destruction. Further delineation of the Wnt signaling pathway in arthritic progression may provide future therapie...

Scientists find microRNAs regulate plant development

...icroRNAs control the accumulation of transcription factor proteins that regulate the expression of genes in ...ulation. One of these targets is the transcription factor AUXIN RESPONSE FACTOR17 (ARF17), which is thought to repress the expression of a number of other gen...

Anthrax inhibitors identified by Burnham team

...ied inhibitors of the anthrax toxin, termed lethal factor ("LF") that could be developed into an emergency treatment for exposure to inhalation anthrax. These findings will be published by the Proceedings of the National Academy of Sciences by Early Edition at the journal's website the week of June 20th. B...

Attacks of King George III's madness linked to key metabolism molecule

...tacks. "We found that PGC-1 alpha is an important factor controlling the expression of ALAS-1 in the fasted and fed liver," the authors write. "Moreover, we showed that hepatic [in the liver] PCG-1 alpha is a major determinant of the severity of acute porphyric attacks in mouse models of chemical porphyria...

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