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Tag: "expressed" at biology news

Gene expression profile helps predict chemotherapy response in ovarian cancer patients

...ology known as microarray analysis, in which genes expressed by cancer cells are labeled and applied to a glass...r tissue obtained at a patient's initial diagnosis expressed a gene profile predictive of findings at second-look surgery. (Second-look surgery is currently the ...

Scientists crack code for motor neuron wiring

...id attention to the fact that these genes are also expressed in the spinal cord." Earlier work performed by Das...bodies that react with each of the 21 Hox proteins expressed by spinal cord motor neurons was an important technical advance that enabled the researchers to crac...

Researchers develop new method to help find deadly malaria parasite's Achilles heel

...e, and the Fields group analyzed only the proteins expressed in the phase that infects human red blood cells, a...ause only a subset of the Plasmodium's proteins is expressed in the erythrocytic stage. However, he noted that the parasite's asexual-phase is actually enriched ...

Argonne researchers confirm lead in Beethoven's illness

..." said Walsh. In fact, in a letter to a friend, he expressed the wish that after his death, researchers would use his remains to help determine the cause of his illness so that others would not have to suffer as he did. "Beethoven suffered from bad digestion, chronic abdominal pain, irritability and depression...

MicroRNA may have fail-safe role in limb development

...ted to actual growth processes. "We found miR 196 expressed only in the hindlimbs of mice, not the forelimbs - in other words, the feet but not the hands," said Brian Harfe, Ph.D., an assistant professor of molecular genetics and microbiology in the College of Medicine and a member of the UF Genetics Institut...

Interactive 3-D atlas of mouse brain now available on web

...etabolically active and where particular genes are expressed -- and for making quantitative anatomical comparisons with other, genetically engineered mouse strains," said project leader Helene Benveniste, who is a researcher in Brookhaven's medical department and a professor of anesthesiology at Stony Brook Un...

Genetic key to growth of new arteries is identified

...e specific DNA sequences of the MMP2 gene that are expressed when new arteries are grown. The study appears in the November 8 issue of the Proceedings of the National Academy of Sciences. "It is not clear why some patients grow new arteries in response to an arterial blockage and others do not," observes Sar...

Common molecular 'signature' identified in solid tumors

...olinia and George Calin found 137 different miRNAs expressed in at least half of the cancers, with 43 miRNAs allowing scientists to distinguish the difference between normal and malignant tissue. Further tests showed that 21 of the distinguishing miRNAs were deregulated in at least three of the cancers ?and ...

UF scientists reveal ancient origin of vertebrate skeleton

...ysis to demonstrate two type II collagen genes are expressed during the development of the lamprey's cartilaginous skeleton. In addition, they isolated a gene called Sox9, a regulator of collagen gene activity in vertebrates. The results indicate the collagen-based skeleton evolved before the jawed and jawles...

Neurons find their place in the developing nervous system with the help of a sticky molecule

... for Biological Studies have identified a molecule expressed on the surface of certain migrating neurons that h...borate connections. They also showed that MDGA1 is expressed on subpopulations of migrating neurons throughout the developing nervous system, including layer 2/3...

New Rotavirus vaccine joins routine infant immunization schedule

...visits at ages two, four and six months. Merck has expressed a commitment to working with the global public health community to make the Rotateq vaccine available to infants and children worldwide. ...

Powerful new tool for studying brain development

... points and show where and when specific genes are expressed at each of four developmental stages. Gene express...o discovers a previously unrecognized gene that is expressed during brain development can rapidly determine how it fits into the overall scheme of brain developm...

Master genetic switch found for chronic pain

...unx transcription factors. Runx1 was known to be expressed only in sensory nerve cells called "nociceptive" c...ryonic development, the gene is characteristically expressed in pain-receptor cells involved in neuropathic pain. When they knocked out the gene, they found that...

Gene needed for butterfly transformation also key for insects like grasshoppers

...ch don't have a pupal stage. "We found that it is expressed throughout the nymphal stages, and that it is also required for change," said Deniz Erezyilmaz, a UW biology research associate. "So it looks like metamorphosis evolved in insects by restricting the expression of the broad gene to a short but intense...

UF scientists reveal ancient origin of vertebrate skeleton

...ysis to demonstrate two type II collagen genes are expressed during the development of the lamprey's cartilaginous skeleton. In addition, they isolated a gene called Sox9, a regulator of collagen gene activity in vertebrates. The results indicate the collagen-based skeleton evolved before the jawed and jawles...

Powerful technique for multiplying adult stem cells may aid therapies

...iated as angpt12 and angpt13, were also abundantly expressed in these stem-cell supporting cells. When Zhang combined these two proteins with IGF-2 and added them to hematopoietic stem cells, the result was a 30-fold increase. "People have been culturing and working with these cells for years, and never befo...

The evolution of food plants: Genetic control of grass flower architecture

... The group found that the ra2 gene is transiently expressed early in development of the maize inflorescence. Analysis of gene expression in a number of different mutant backgrounds placed ra2 function upstream of other genes that regulate branch formation. The early expression of ra2 suggests that it function...

Medical experts: US unlikely to have enough vaccines to stop avian flu

...de Bruin said. Although the federal government has expressed a commitment to open communication about these risks, its messages have not yet been scientifically evaluated, according to Fischhoff. ...

Darkness unveils vital metabolic fuel switch between sugar and fat

...emained in the pancreas and stomach. The gene was expressed in the livers of some mice from a double-mutant st...types of mouse kept in constant darkness had mClps expressed not only in their livers but in all peripheral tissue except the brain and kidneys. "This is the ...

New hybrid virus provides targeted molecular imaging of cancer

...that the reporter and therapeutic genes were being expressed throughout the tumors in the animals," Gelovani says. "This is an example of the so-called "theragnostic" approach, a combination of the words therapeutic and diagnostic." Next, the international collaborative research team plans to evaluate the saf...

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