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Tag: "expressed" at biology news

A gene's first 'kiss' sets off that affair known as puberty

...ates." Besides learning that GPR54 and KiSS-1 are expressed inside the hypothalamus of primates at the time of puberty, the researchers also found that by giving animals kisspeptin they could, essentially wake up the reproductive hormones from their childhood hibernation. Within 30 minutes of kisspeptin being...

Newly-discovered class of genes determines ?and restricts ?stem cell fate

...d store the pigments in the skin and hair ?is also expressed in adult stem cells in the skin. "Our findings to...ng genes that previously had only been known to be expressed in a developing embryo. That was the first clue that we were on to something new." Epstein and colle...

Ancient olfaction protein is shared by many bugs, offering new pest control target

...viously shown that of 62 odorant-receptor proteins expressed by fruit flies, 61 are exclusively expressed in non-overlapping sub-populations of neurons, indicating that these proteins participate in sensing...

Live Recombinant Adenovirus Vaccine Technique Explored

... gene into a live adenovirus such that it would be expressed using the virus' own late-gene expression machinery. L1 is expressed at very high levels in some recombinants. Dr. Ketner believes that the replicating live recombinant...

Gene therapy converts dead bone graft to new, living tissue

...in living bone, called RANKL and VEGF, were barely expressed around the dead bone. He then modified a harmless virus to carry these genes, devised a method of freeze-drying a paste containing the virus so it could be easily handled, and painted it directly onto a bone graft during surgery. Numerous tests in m...

Scientists decipher genome of fungus that can cause life-threatening infections

...A differences and differences in when the genesare expressed (turned on or off) ?may account for the disparity invirulence.Among the surprising findings of the study were the complex genestructures discovered in C. neoformans that are unlike those found inpreviously sequenced yeasts and are reminiscent of the ...

First 'atlas' of key brain genes could speed research on cancer, neurological diseases

...or brain areasthat shows what regulatory genes are expressed in those specificlocations,?said Quifu Ma, PhD, of... determined that more than 1,000 of these TF’swere expressed in the brains of developing mice.Using genetic probes to investigate thin sections of mouse brains, ...

Vital step in cellular migration described by UCSD medical researchers

... scientists noted that alpha4 integrins are widely expressed in neural crest cells, immune system leukocytes (such as T cells), striated and smooth muscle, and neurons. For this reason, they believe the mechanism used by alpha4 integrins to localize Rac activity may participate in a wide variety of cell migrat...

Genetically modified natural killer immune cells attack, kill leukemia cells

...a said. "By genetically modifying NK cells so they expressed the CD19 receptor, we made them specifically effective against ALL cells." A potential clinical application for the technology developed in this study is in leukemia patients who are treated with hematopoietic (blood cell-forming) cell transplantati...

Researchers trace evolution to relatively simple genetic changes

...cule called ectodermal dysplasin. This molecule is expressed in ectodermal tissue during development and instructs certain cells to form teeth, hair and sweat glands. It also seems to control the shape of - bones in the forehead and nose. Now, Kingsley said, "it turns out that armor plate patterns in the fish...

Scientists reveal molecular secrets of the malaria parasite

...he parasite genes evolve mostrapidly when they are expressed in the mammal hosts (human/mouse). Thatmay represe...is particularly interestingbecause these proteins, expressed early in the mosquito, are the targetof transmission-blocking vaccines" —that is, vaccines which rai...

Octopuses occasionally stroll around on two arms, UC Berkeley biologists report

...cule called ectodermal dysplasin. This molecule is expressed in ectodermal tissue during development and instructs certain cells to form teeth, hair and sweat glands. It also seems to control the shape of - bones in the forehead and nose. Now, Kingsley said, "it turns out that armor plate patterns in the fish...

Tiny scaffolding allows stem cells to become working fat cells

...ing fat cells, and from that proved that the cells expressed the normally expected array of genes, and subsequent proteins and did so as well as occurs in normal tissue. So far, the researchers have kept the cells alive and thriving for several months and hope to maintain them for up to a year. "We know that ...

Research Using Mouse Models Reveals A Novel Key Player In The Initiation Of Colon Cancer

...n a transcription factor called Foxl1 that is also expressed in the colon, but in a different layer of cells, adjacent to the epithelium, called the mesenchyme. They had seen that mice that are deficient for the Foxl1 protein show a similar accumulation of the beta-catenin protein in the epithelium layer, yet ...

RNA project to create language for scientists worldwide

...les as "the software controlling how the genes are expressed to make proteins." They are unique in being able to store and transmit information as well as process that information. The continuous discovery of new RNA molecules with novel biological functions is beginning to show that RNA plays far more roles ...

South America's vast pantanal wetland may become next everglades, UNU experts warn

... by UNU-PREP and UNU IAS in Brazil in October 2003 expressed their willingness to draft a treaty for the sustainable management of the Pantanal wetland. "The challenge now is to translate this will into action." ...

UF Researchers Map Bacterial Proteins That Cause Tooth Loss

...urnal Proteomics. “Determining which proteins are expressed in greater levels in the mouth has allowed us to g...called ‘hypothetical?proteins in P. gingivalis are expressed and have specific functions.?/p> Until now, scientists had identified less than 2 percent of the...

Applied Biosystems Introduces Advanced Gene Expression Service Provider Program

...while using less sample for the detection of genes expressed at very low levels compared with conventional fluorescent microarrays. The system uses a chemiluminescence-detection instrument, software, and chemistries to deliver unambiguous gene results that are highly sensitive and reproducible. The PCR proces...

Harnessing microbes, one by one, to build a better nanoworld

...while using less sample for the detection of genes expressed at very low levels compared with conventional fluorescent microarrays. The system uses a chemiluminescence-detection instrument, software, and chemistries to deliver unambiguous gene results that are highly sensitive and reproducible. The PCR proces...

Asthma gene clusters identified

...s goal would be to identify gene profiles that are expressed during asthma that are exacerbated by different factors, such as exercise, viral infection or allergic triggers. In doing so, physicians will be in a better position to assess and treat a patient's asthma with greater precision. "As we learn more ab...

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