Specialized immune-system B cells play double-barreled role
..., the two mouse strains enabled the researchers to explore the consequences of too many or too few B-1a cells. Also, the strain lacking CD19, and therefore B-1a cells, enabled the researchers to isolate sufficient numbers of pure B-1b cells for study. The researchers studied how the immune systems of the tw...ORNL, UC Berkeley unravel real-world clues to Earth's mysteries
...nction, a great deal of work remains to more fully explore the spatial and temporal aspects of how such a community grows, ages and adapts to its environment. ...Scripps research scientists solve structure of a critical innate immune system protein
...s great insights into experiments we can design to explore their function. In advance, we wouldn't have known where to look." In addition to helping scientists better understand how TLRs work, the structure may also help scientists take steps toward improving human health, since TLRs are implicated in a num...New tool reveals secrets of migrating cells
...hanged the way immunologists think about how cells explore their environment, how they signal to each other, ... traveling thousands of microns in an hour as they explore the thymus. The new experiments, conducted primarily by Witt, suggest that this exploration probabl...Major advance made on DNA structure
... letters, it's an actual structure that we have to explore if we ever hope to understand biological function. This is a significant step forward, a milestone in DNA structural biology." In the early 1950s, two researchers at Cambridge University ?James Watson and Francis Crick ?made pioneering discoveries b...Tufts researchers shine light on firefly mysteries
...f fireflies. For the first time, researchers will explore the question of whether male fireflies' flashing light ?previously shown in one species to indicate superior physical and genetic quality ?has evolved in another species to provide misinformation to prospective mates. In other words, are some male fi...Disease diagnosis, bioengineering covered at state nano summit
...ors. Both presenters and attendees will be able to explore the specific research needs and opportunities associated with the multidisciplinary field that is nanotechnology. Krause's work deals with the significant effort in bionanotechnology today being devoted to the use of naturally occurring proteins in ...Going To Extremes To Improve Human Health
...r's potential is enhancing researchers' ability to explore fatigue. "Physical and mental fatigue may not be commonly perceived as work hazards, but fatigue often is a fundamental cause of accidents and injuries," Minson said. Minson's work, which pertains to a range of disease conditions such as diabetes, i...Insects develop resistance to engineered crops
...Bt plants and Bt-resistant insects allowed them to explore the concurrent use of single- and dual-gene Bt plants in a way that could not be done with cotton or maize, although their results are relevant to these widely grown plants. First, the researchers bred moth populations in which a low percent of the ...... make comparisons meaningful but with an easier to explore nerve layout. MBL researchers have used the toadfish as a model for research into neurotransmission; certain hearing and balance disorders, including Meniere's disease; and motion sickness and dizziness. Surf clam (Spisula solidissima): Surf clam eg...New clue to cocaine addicts' quirky behavior
...avioral studies on the cocaine-sensitized rats, to explore the behavioral effects of this disruption. In these studies, they placed the rats in a plus-shaped maze. The rats were taught that in response to a visual cue they should turn left or right toward one arm or the other of the maze to obtain a piece of...Deep sleep short-circuits brain's grid of connectivity
...Tononi says. "So what could be responsible?" To explore the breakdown of consciousness during sleep, Tononi and his colleagues capitalized on a new technology - transcranial magnetic stimulation - that permits precise, non-invasive activation of small regions of the brain. Subjects are also equipped with ...Frog peptides block HIV in lab study
...Tononi says. "So what could be responsible?" To explore the breakdown of consciousness during sleep, Tononi and his colleagues capitalized on a new technology - transcranial magnetic stimulation - that permits precise, non-invasive activation of small regions of the brain. Subjects are also equipped with ...Space matters: Estimating species diversity in the fossil record
...udies can more easily correct for area effects and explore these issues. And given the parallels between species-area relationships in paleontology and ecology, collaborations across disciplines may offer valuable insights into ecological dynamics through time. Citation: Barnosky AD, Carrasco MA, Davis EB (...NIH creates nationwide network of molecular libraries screening centers
...for the first time, enable academic researchers to explore novel ideas and enable progress on a broad front a...ening effort will eventually enable researchers to explore the hundreds of thousands of proteins believed to be encoded by the approximately 25,000 genes in th...New research could help us deliver genes for new bone formation
.... Professor Oreffo added "It is important that we explore the potential of new methods and biotechnologies to help meet the healthcare needs of an ageing population. Although research such as this is currently a number of years from being available to patients it is important that fundamental research is ca...Public collections of DNA and RNA sequence reach 100 gigabases
...vel of their genetic code, several groups began to explore the possibility of developing a public repository for sequence information. In the early 1980s this led to the launch of two databases: the first was the EMBL Data Library, based at the European Molecular Biology Laboratory [EMBL] in Heidelberg, Germ...Discovering an ecosystem beneath a collapsed Antarctic ice shelf
...ollapsed Larsen Ice Shelf will allow scientists to explore the uncharted life below Antarctica's floating ice... as Lake Vostok, also in the Antarctic, to further explore the little-understood connection where ice sheets, the seafloor, and circulating water meet. The res...A novel method to measure circadian cycles
...the method developed by Schibler and colleagues to explore questions about the exact relationship between the suprachiasmatic nucleus and the circadian rhythms of cultured fibroblast cells. Just how does this brain structure coordinate genetic imperatives with environmental input including light fluctuations...'Shifty-eyed' Monkeys Offer Window Into Brain's Social Reflexes
...ial-processing regions of the monkeys' brains, and explore whether the resulting behaviors mimic the symptoms of autism. Also, he said, the researchers can explore the environmental contribution to autism by studying the effects of manipulating the animals' social...