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Tag: "explains" at biology news

World-first Living Donor Islet Cell Transplant A Success; Procedure Offers Promise For Diabetics

...ted islets began producing insulin within minutes, explains Dr. Shapiro. "The reason I'm so excited about this is because normally the Edmonton Protocol is done with islets from brain-dead organ donors. Those islets are often severely injured from cold storage, transport time and the pancreas is severely dama...

Great White shark evolution debate involves WSU Lake Campus geology professor

...possessing teeth that were up to six inches long," explains Ciampaglio. "However, our research, which is based on analyzing fossils of several hundred shark teeth, shows that the Great White shares more similarities with the mako shark." He added that because sharks regularly replace their teeth, it is relati...

McGill researchers shed light on formation of carcinogen in food

...Yaylayan and graduate student Carolina Perez Locas explains the presence of this chemical in a wide range of f...or sugars are broken down by the heat of cooking," explains Dr. Yaylayan. "Normally, furan is a volatile chemical which tends to quickly evaporate. However, whe...

New drug shows promise as powerful anticancer agent

...quired by a tumor cell to complete cell division," explains lead author Dr. E. Premkumar Reddy from Temple University School of Medicine. "One such molecule appears to be Plk1." Dr. Reddy and colleagues examined the effects of Plk1 inhibitor ON01910 on tumor growth in several animal models. The researchers f...

Love's all in the brain: fMRI study shows strong, lateralized reward, not sex, drive

...ciated with motivation to acquire a reward. Brown explains some of these findings, commenting that "when our ...me of the same brain systems are involved." Study explains second half of Darwin's puzzle, sexual selection & 'eyes of the beholder' "Darwin and many of h...

Researchers report new pro-inflammatory role for anti-inflammatory enzyme

...olecule released (predominantly) by immune cells," explains Dr. Adrian J. Hobbs of University College London. ...cells and growth of vascular smooth muscle cells," explains Dr. Hobbs. "iNOS is not expressed under normal physiological conditions, but is up-regulated for hos...

Biologists discover why 10% of Europeans are safe from HIV

...election pressure on the CCR5-delta32 mutation and explains why it occurs today at its highest frequency in Scandinavia and Russia." ...

First North American Encapsulated Islet Transplant without Long-term Immune Suppression into a Patient with Type 1 Diabetes

...election pressure on the CCR5-delta32 mutation and explains why it occurs today at its highest frequency in Scandinavia and Russia." ...

Aggressive aquatic species invading Great Lakes

...logperch and easily take over contested shelters," explains Balshine. The researchers found that round goby abundance has increased dramatically throughout the Great Lakes basin since its arrival from the Black and Caspian Seas in 1990. Previous research has shown that round gobies eat eggs and young of vari...

FDA Works To Speed The Advent Of New, More Effective Personalized Medicines

...ring regulatory decision making. The guidance also explains a new mechanism for industry to voluntarily submit research data to further the scientific exchange of information as we move into more advanced areas of pharmacogenomic research. The voluntary data, which will be reviewed by an internal, agency-wide...

Scientists discover that three overlapping signals in embryo help get the backbone right

...at the University of California, Berkeley, finally explains an 80-year-old observation that revolutionized the way biologists think about embryonic and fetal development and set the stage for the stem cell debate. That 1924 observation in newts by Hans Spemann and Hilde Mangold earned Spemann the Nobel Prize...

Multiple-drug resistant gene expression pattern predicts treatment outcome for pediatric leukemia

...this cause of treatment failure in childhood ALL," explains Dr. Evans. ...

Signs of aging: Scientists evaluate genes associated with longevity

...ucial for longevity. "Aging is a complex process," explains Dr. Brooks-Wilson. "It is commonly believed that a variety of genes and metabolic pathways contribute to the deterioration of cells, tissues and organisms during aging." In an effort to perform a comprehensive analysis of gerontology-related genes, ...

MUHC researchers make cancer target breakthrough

...al nutrient necessary for growth of cancer cells," explains Dr. Rima Rozen, principal investigator of the new ...ives us hope that this might also work in humans," explains Dr. Rozen. The research, funded by Strida Pharma--a McGill University spin-off company--also indica...

Disease progression model of pancreatic cancer developed by Penn researchers

...e linked to the progression of pancreatic cancer," explains Hingorani. "In trying to understand what events are required to create and support invasive and metastatic disease, we hope to translate our findings into better therapies," states Hingorani. The study was funded in part by the National Institutes o...

New polysaccharide may help combat multidrug resistance in cancer

...proliferation, invasiveness, and drug resistance," explains Dr. Toole. "Hyaluronan oligomers are non-toxic, non-immunogenic, and readily applicable to several proliferative disease processes, especially cancer. We are hoping that hyaluronan antagonists can be used in conjunction with chemotherapy such that mu...

Of mice and men's (and women's) contraceptives

...m cells differentiate into mature sperm and eggs," explains Hecht. "An equally likely possibility is that the absence of MSY2 disrupts the timing of how specific mRNAs are used during germ cell differentiation. As cells become mature sperm, there's a precise order of synthesis of many essential proteins neede...

Unchecked DNA replication drives earliest steps toward cancer

..."Cancer progression is driven by these mutations," explains Thanos D. Halazonetis, D.D.S., Ph.D., professor in the molecular and cellular oncogenesis program at Wistar and senior author on the Nature study. "Once you have the initiating event, you will have constant DNA breaks. These DNA breaks create more mu...

Breakthrough isolating embryo-quality stem cells from blood

...ding to the strength of their cytoskeletons. Watts explains that such an advance could have far-reaching consequences for medical treatments. "We could add significantly to our knowledge of stem cell biology toward developing cellular therapies," he says. The optical stretcher can already test 3,600 cells pe...

A new way to share models of biological systems

...it and share new models when they were developed," explains the EBI's Nicolas Le Novère. "The BioModels database aims to address these issues." The first step was to develop a standard way of describing such models. The Systems Biology Markup Language (SBML), an open-source computer language developed by the...

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