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Tag: "explains" at biology news

Genes In The Interferon System Important In Systemic Lupus Erythematosus

...locking the function of the thyrosinkinaseenzyme," explains Lars Rönnblom.The other gene codes for a transcription factor, which also plays animportant role in regulating the interferon effect. Further functionalanalyses will be necessary to map the molecular mechanisms in detail.Besides the Rheumatology Clin...

UCSB scientists probe sea floor venting to gain understanding of early life on Earth

...e Foundation, a major funder of this work. The NSF explains that subseafloor ecosystems may represent both the cradle of life on Earth and a model for the exploration and discovery of life on other planets. "We are highly conscious of the importance of microbes in the grand scheme of things," said Haymon. "I...

Elusive HIV shape change revealed; Key clue to how virus infects cells

...l-ordered crystals you get a very blurry picture," explains Harrison. "It took a very long time, and lots of computational work, to get that picture to sharpen up enough to get an answer." One of the lab's first steps will be to determine which shape of gp120 ?bound to the CD4 receptor, or unbound ?is recogn...

Newly-discovered class of genes determines ?and restricts ?stem cell fate

...s occurring in resident stem cells in adult skin," explains Jon Epstein, MD, Professor of Medicine, Cardiovascular Division. "These few rare stem cells were expressing genes that previously had only been known to be expressed in a developing embryo. That was the first clue that we were on to something new." E...

The secret to longevity in tubeworms

...ypothetical interaction provides real benefits and explains real observations, the authors hope to stimulate further research into the biology of the enigmatic and beautiful L. luymesi. ### Citation: Cordes EE, Arthur MA, Shea K, Arvidson RS, Fisher CR (2005) Modeling the mutualistic interactions between tu...

Another Look Finds Promising Proteomics Test is Not Biologically Plausible

...ein pattern “is biologically implausible.?Baggerly explains that discriminatory peaks appear to be spread across the entire m/z spectrum in the second data set, but “changes in protein expression associated with cancer should affect only a few specific peaks, not the entire spectrum.?/p> Furthermore, the ...

New species from old data

...ein pattern “is biologically implausible.?Baggerly explains that discriminatory peaks appear to be spread across the entire m/z spectrum in the second data set, but “changes in protein expression associated with cancer should affect only a few specific peaks, not the entire spectrum.?/p> Furthermore, the ...

Cracking the olfactory code in bees

...ein pattern “is biologically implausible.?Baggerly explains that discriminatory peaks appear to be spread across the entire m/z spectrum in the second data set, but “changes in protein expression associated with cancer should affect only a few specific peaks, not the entire spectrum.?/p> Furthermore, the ...

Signaling protein builds bigger, better bones in mice

...ein pattern “is biologically implausible.?Baggerly explains that discriminatory peaks appear to be spread across the entire m/z spectrum in the second data set, but “changes in protein expression associated with cancer should affect only a few specific peaks, not the entire spectrum.?/p> Furthermore, the ...

Scientists find missing enzyme for tuberculosis iron scavenging pathway

...tics have sugar rings with amino groups attached," explains Dr. Baker. "The N-acetyltransferase chemically mod...nnot acquire the iron that it needs for survival," explains Dr. Baker. "Importantly this seems to be true even of the bacteria that are taken up by macrophages ...

Gene therapy converts dead bone graft to new, living tissue

...ivities cause microscopic fractures in our bones," explains Schwarz. "Those fractures are normal and healthy, and our bones re-knit them constantly. But when the bone is dead, there is no healing, and those tiny fractures begin to accumulate until finally, perhaps in 10 years, the implanted section collapses,...

Antibiotic Resistant Bacterium Uses Sonar-like Strategy to “See?Enemies or Prey

... in the December 24 issue of Science, this finding explains howsome bacteria know when to produce a toxin that makes infection moresevere. It may lead to the design of new toxin inhibitors. “Blocking orinterfering with a bacterium’s “detection?mechanism, should preventtoxin production and limit the severity o...

Novel Therapy Tested in Mice Could Chase Away Cat Allergies

...Feline domesticus, for its human and feline parts, explains principal investigator Andrew Saxon, M.D., of UCLA. The cat allergen end of GFD binds to antibodies on the surface of the cell. The human end of GFD links to a different cell surface protein (called FcgRIIB) that interrupts the allergic response. Dr...

Why do insects stop 'breathing'? To avoid damage from too much oxygen, say researchers

...these safe values," Bradley said. "This hypothesis explains the respiratory pattern of insects in different environments in ways that previous models can't." Two previous models for explaining why insects punctuate their breathing with periods of closure are (1) such discontinuous breathing reduces water los...

Scientists discover that host cell lipids facilitate bacterial movement

...it reaches the peripheral or outer cell membrane," explains Dr. Frederick Southwick of the University of Flori...that Listeria is capable of inside-out signaling," explains Dr. Southwick. "Most signals arise from molecules binding receptors on the outside of the cell. In t...

Scientists solve structure of key protein in innate immune response

...various molecules from pathogenic microorganisms," explains Dr. Jie-Oh Lee of the Korea Advanced Institute of ...ock agents for a long time without clear success," explains Dr. Lee. "Since LPS is an important inducer of septic shock, blocking LPS receptors such as CD14 are...

Sequencing of marine bacterium will help study of cell communication

...any different bacteria use quorum sensing. Stevens explains that cells release autoinducer molecules. The numbers of these signal molecules increase with cell density, until they initiate various reactions, such as light production ?or, in a pathogen, the release of toxin once a certain level of bacteria buil...

Children's taste sensitivity and food choices influenced by taste gene

...her than rebelliousness or defiance of authority," explains Reed. The research continues and extends Monell's long-term research program exploring development of taste and flavor preferences during childhood, a critical time for learning about food. Mennella comments, "Our previous studies focused on how ear...

Protein offers way to stop microscopic parasites in their tracks

...e when the immune system wanes or is compromised," explains L. David Sibley, Ph.D., professor of molecular microbiology at Washington University School of Medicine. For the study, researchers in Sibley's lab collaborated with Sinisa Urban, Ph.D., assistant professor of microbiology at Harvard University. Sib...

Effective Cancer Treatments Follow The Clock

...archers have discovered a molecular mechanism that explains why sensitivity to anti-cancer drugs changes with the clock. They said their findings could lead to new drug treatments that may be more effective because they harness the power and precision of the body's internal clock. The research team, which in...

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