experiments 2 5

Tag: "experiments" at biology news

Pair of cancer genes found to drive both cell migration and division

...membrane, and the cell can't migrate properly. In experiments with single-celled amoebae, Devreotes and his team learned that PTEN and PI3K do the same thing to PIP3 in dividing cells. When a normal cell prepares to divide, it first doubles its genetic material, and then creates a "furrow" down the middle, cutt...

Researchers Closer To Helping Hearing-Impaired Using Stem Cells

...hino said she and her colleagues are beginning new experiments to test the feasibility of marrow stromal cell transplantation to stimulate the growth of the nerve cells that are often missing from the inner ears of patients with profound hearing loss. “Sonic hedgehog and retinoic acid are molecules found in emb...

Researchers Identify Cause of Early Bird Sleep Disorder

...e, their circadian rhythm, he added. But follow-on experiments in fruit flies and mice yielded results that are i...son's sleep behavior. Evidence from tissue culture experiments with the second gene suggests the change causes a protein -- an enzyme called a kinase that is made ...

Computational Tool Predicts How Drugs Work In Cells, Advancing Efforts To Design Better Medicines

... cells. Their algorithm predicted, and subsequent experiments verified, that PTSB acted on thioredoxin and thioredoxin reductase, findings that not only validate the tool’s capability but could also pave the way to investigations of a potentially new class of therapeutic compounds. In addition to Gardner, Coll...

Climatologists discover deep-sea secret

...firmed with detailed data obtained from scientific experiments using weather records from the past. This is the first evidence showing that waters in the southern hemisphere play an active role in sudden climate changes. Today's climate in Europe and North America is greatly influenced by the gulf stream. This ...

Life detection instrument passes key test on road to Mars

...Honda generator providing power, they set up their experiments and, with six other colleagues, tested the integrated subcritical water extractor together with the MOA on samples from popular test sites such as the "Rock Garden" and the "Soil Pit." One thing they learned is that with low environmental levels of ...

New understanding of cell movement may yield ways to brake cancer's spread

...rnally choreographing directed cell migration. The experiments were conducted in several widely used laboratory models, but the molecule exists in nearly all animals, from roundworms to mammals, and likely has a conserved function throughout species. Knowing exactly what triggers cellular migration can help deve...

Gene silencing technique offers new strategy for treating, curing disease

...ile the PNAs are synthetic," Dr. Corey said. "The experiments worked beautifully," he said. "It's hard to believe that this strategy would work so well if nature wasn't doing it already." The researchers designed their RNA to match up with and target specific genes. "It's possible that the body is making the R...

Team Invents Device For Weighing Individual Molecules

...few billionths of a trillionth of a gram. In their experiments this represents about thirty xenon atoms-- and it is the typical mass of an individual protein molecule. "We hope to transform this chip-based technology into systems that are useful for picking out and identifying specific molecules, one-by-one--fo...

Protein synthesis can be controlled by light, opening way for new scientific, medical applications

... "Our technique will enable scientists to conduct experiments aimed at understanding the mechanisms of learning and memory at the molecular and cellular level," said Dore. The technique could also be used in drug discovery and development, though it is much more likely to be used in advancing knowledge about b...

The making and breaking of microtubules

...dynamic instability, opening opportunities for new experiments testing the physiological roles of these microtubule intermediates in the cell." Richard Rodewald, a program officer and cell biologist at the National Institute of General Medical Sciences, which funded the research, noted that "these studies provi...

Program finds lost genes in nematode genome

...ome sequence, using that as a hypothesis designing experiments to test the hypothesis. The traditional modus operandi is a data-driven approach that starts with sequencing a random sample of tens of thousands of cDNA clones. Whereas the traditional approach leads to sequencing some genes thousands of times and o...

UI researcher studies deafness in fruit flies, humans

...olecule is used, scientists will be able to design experiments to test specific mechanisms that have been hypothesized. Eberl says, "These experiments are next to impossible in humans, but quite feasible in the fruit fly." "Understanding how this pro...

Combination therapy leads to partial recovery from spinal cord injury in rats

...is case, specialized cells and growth factors. The experiments also used a combination of outcomes -- physiology, behavior, and anatomy -- to point clearly at myelination as the cause for improved function," says Naomi Kleitman, Ph.D., the NINDS program director for the grants that funded this work. "The study a...

UNC plant researchers discover proteins interact to form hair-trigger protection against invaders

...uses. "Contrary to what we thought we'd find, our experiments showed that at least three different proteins work in concert with one another in tug-of war or teeter totter-fashion to keep plant defenses in a state of constant readiness," said Dr. Jeffrey L. Dangl, John N. Couch professor of biology in UNC's Col...

Researchers develop promising new gene network analysis method

...frame. Analysis of gene activity generated in the experiments revealed 1,191 possible players in the c-Myc gene ...stem: humans. The overall concept ?the time series experiments and the combination of statistics and network theory ?is quite novel. This should be an important ne...

FDA approves more generic AIDS drugs

...uses. "Contrary to what we thought we'd find, our experiments showed that at least three different proteins work in concert with one another in tug-of war or teeter totter-fashion to keep plant defenses in a state of constant readiness," said Dr. Jeffrey L. Dangl, John N. Couch professor of biology in UNC's Col...

Mechanism for the captation of nutrients in plants- unknown to date

..., Plant Cell Physiology, will enable the design of experiments aimed at enhancing vegetable species in the intere...than that incorporated via endocitosis. Thus, the experiments carried out showed the existence of processes independent of nutrient captation: a saccharose penetr...

Bioinformatics reveals new gene regulation system

...rchers simultaneously showed through 'wet' biology experiments in Streptomyces bacteria that a transcription factor from this family represses Nrd gene expression in the living bacterial cell, confirming the Russian researchers' predictions. Confident that they had identified a new repressor of bacterial genes, ...

Researchers extend mouse lifespan by protecting against free radicals

...ly been able to extend the lifespan of mice in lab experiments by managing their diets and reducing their caloric intake. Another method relied on the restriction of a growth factor, but a side effect was that the mice suffered from dwarfism. However, neither of those methods of elongating the mouse lifespan was...

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