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Tag: "experiments" at biology news

Effective Cancer Treatments Follow The Clock

...rent times of the day,?said Takahashi. The initial experiments with normal mice, performed by Antoch during her tenure in Takahashi's lab, confirmed that animals treated with CY survived better when they received treatment in late afternoon than those whose treatments were initiated early in the morning. Antoch ...

Hirsute Or Hairless? Two Proteins May Spell The Difference

...uds, the precursors of hair follicles, form. Their experiments point to two key actors in a signaling pathway that molds a targeted cluster of cells into a hair bud. During the budding process, overlapping signaling pathways from two adjacent embryonic cell layers—the epithelium and the mesenchyme—direct morpho...

Probing the promise and perils of nanoparticles

...he cell," said Banaszak Holl. But early results of experiments with living cells suggest that the same types of n...called polycation-mediated endocytosis. But Hong's experiments suggest that nanoscale hole formation may be at least as important in allowing materials to travel t...

Flocking together: Study shows how animal groups find their way

...e one, Couzin said The researchers extended their experiments by introducing two subgroups with differing prefer...n and colleagues are now testing their findings in experiments with animals, such as schools of fish in which a few have been taught to seek food in a certain loca...

Liposome finding implies electrical effect on cell development

...erve cells. Hayes will present the results of the experiments at a 2 p.m. March 15 session entitled "Colloids in Complex Fluids" at the American Chemical Society meeting in San Diego. In the experiments, the researchers placed liposomes in a droplet of water and applied very low electric fields (5-10 volts per...

Robot-based system developed at Carnegie Mellon detects life in Chile's Atacama desert

...acama as a research test bed. Scientists conducted experiments with Hyperion to determine the optimum design, sof...n for a robot that would be used in more extensive experiments conducted in 2004 and in 2005. Zoë, a brand new robot, was developed in response to what was learned...

Transgenic plants remove more selenium from polluted soil than wild plants, new tests show

...oil. Because USDA regulators are scrupulous about experiments involving genetically modified plants in the field, the researchers took great care to minimize the transfer of genes through pollen. "Before we started the study, we took aerial surveys to ensure that no other mustard-related plant species were bei...

A human parasite with a streamlined mitochondrion

... far fewer jobs than our own mitochondria. Further experiments performed by the team reveal that the Entamoeba carrier can only transport ADP and ATP, suggesting that it could fuel energy-requiring reactions within the mitosome but might not perform other functions. The work suggests that the Entamoeba mitosome ...

Fibril Shape Is The Basis Of Prion Strains And Cross-species Prion Infection

...San Francisco came to the same conclusion in their experiments with yeast. They too discovered that the particula...shape differences at much higher resolution. Their experiments also used a shortened version of the mammalian prion protein, so they hope to test the fibril factor...

New component of the 'brakes' on nerve regeneration found

...ptor proteins--called TNF receptors--as p75. Their experiments revealed that TAJ/TROY is produced throughout the adult brains of mice. Also, they found that TAJ/TROY readily fits into the inhibitory receptor complex and that the resulting receptor complex switches-on the inhibitory machinery within neurons. Also...

New Drugs For Bad Bugs: UF Approach Could Bolster Antibiotic Arsenal

...cent example: Derendorf led a series of laboratory experiments designed to evaluate an investigational, sustained...ision for a product so you don’t do a lot of other experiments to study a compound that later will be dropped ?that alone saves a lot of money.?/p> UF research...

Key mechanism in genetic inheritance during cell division identified

... to cancer and birth defects. From various genetic experiments we know that the activity of a 10-protein complex of kinetochores, called Dam1, is responsible for the faithful segregation of chromosomes during mitosis. While we don't know at this time that ring formation occurs in vivo, we do see in our in vitro ...

Strongest proof yet found for prion hypothesis

... of prion protein necessary for the success of the experiments and opened the door to further TSE studies. According to Soto, it should also soon facilitate creating a much-needed blood test for prions, which would greatly improve current surveillance techniques for mad cow disease and its human form, new-varian...

Two are better than one

...eted Molecular Diagnostics, Westmont, IL, USA. In experiments conducted in vitro and in lab mice, the researchers exposed the cancer cells to two different antibodies that link up to HER2 receptors. In a synergistic action, the antibodies were shown to cooperate rather than compete for distinctly different atta...

Potential Drug Target For Treating Cocaine Abuse Found

...stitute on Drug Abuse (NIDA) report the results of experiments showing that mice treated with a substance similar to the drug benztropine did not show any of the typical hyperactive behavior when later injected with cocaine. This effect wore off after a day. Cocaine produces intense feelings of euphoria by incr...

Nano-bumps could help repair clogged blood vessels

... The researchers already have shown in a series of experiments that bone and cartilage cells in petri dishes attach better to materials that possess smaller surface bumps than are found on conventional materials used to make artificial joints. The smaller features also stimulate the growth of more new bone tissu...

Leprosy microbes lead scientists to immune discovery

...s "adaptive" immunity. Until now, laboratory dish experiments hadn't revealed that the instantaneous or "innate" immune reaction--discovered less than 10 years ago--is mounted by two differently-specialized cells. It had been thought that the initially responding cells were uniformly macrophages, equipped for t...

Used in a new way, RNA interference permanently silences key breast cancer gene

...t it may be possible to use RNAi in more than just experiments that silence genes temporarily," says the study's principal investigator, Ralph Arlinghaus, Ph.D., a professor and chair of the Department of Molecular Pathology. Details of the study appeared in the April 1 2005 issue of the journal Cancer Research....

New understanding of DNA repair may pave way to cancer treatments

...signal" for ATF2. "Later," Dr. Ronai said, "we did experiments that showed the signal was lost because a protein kinase, ATM, modified ATF2 enough to interfere with detection of the ATF2 signal. Soon, work performed by Anindita Bhoumik confirmed that ATF2 is regulated by ATM and that this regulation is central t...

Brain-injury rehabilitation depends on acetylcholine circuitry

...n. Conner and his colleagues were guided in their experiments by earlier studies showing that the cholinergic system in a region called the basal forebrain was associated with normal learning of motor control. To determine whether this same system also played a role in rehabilitation from brain injury, they fi...

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