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Tag: "experiments" at biology news

DNA Molecules Used To Assemble Nanoparticles

...researchers can track their movement. A series of experiments using cell sorters, 3-D microscopes and other tools verified that these dendrimers hit their targets, were admitted into the cells and gave off their signaling light. The self-assembled dendrimer clusters were shown to be well formed and functional. ...

It's not all genetic: Common epigenetic problem doubles cancer risk in mice

In experiments with mice, a team of scientists from the United St...ng of IGF2 and colon cancer in people, the current experiments were designed to find out whether the loss of imprinting is involved in cancer's development or just...

Growth in the sea comes down to a struggle for iron

...pher John Martin reported the first series of iron experiments that indicated iron was indeed the missing ingredi...erway, but scientists have embarked on a series of experiments in three major areas of the world's oceans. "The three areas are the Southern Ocean around Antarcti...

Controversial drug shown to act on brain protein to cut alcohol use

... and Research Center have nowshown definitively in experiments with mice and rats that Ibogaine doesreduce alcohol consumption, and they have determined that it does so byincreasing the level of a brain protein known as glial cellline-derived neurotrophic factor, or GDNF. In a separate study, theydemonstrated th...

Neuronal 'traffic jam' marks early Alzheimer's disease

...oid plaques poison the transport machinery. If the experiments do, indeed, confirm the predictions of the transport hypothesis, then neuronal cultures could prove valuable in testing diagnostic and therapeutic approaches, said Goldstein. The researchers are also analyzing more brain tissue samples from humans w...

Termites feed through good vibrations

...ce. CSIRO entomologist Theo Evans says laboratory experiments have found that termites use their ability to dete...colony. Few workers developed into breeders in the experiments when they were broadcast the termite sourced signals, whereas many workers developed into breeders w...

Timing is everything: First step in protein building revealed

...mpletelyin living creatures, but in our laboratory experiments that is clearlythe case," adds Lorsch. "Even if it isn't released completely in intactcells, our results would indicate that it must be very looselyassociated for translation [protein building] to begin."To monitor what was happening to eIF1, the res...

Study Demonstrates Gene Expression Microarrays are Comparable and Reproducible

...h? The NIH recently demonstrated that microarrays experiments performed in different labs "have a high degree... only slightly lower thancorrelation of duplicated experiments within the same labs. “Thisstudy is a key first step in moving gene expression data fromsmall-scale...

New Technique for Tracking Gene Regulators

... differentconditions,?he said.Previous, individual experiments have identified about 100 places whereCREB binds to DNA and regulates genes in humans, so scientists know itis important, particularly in regulating cell differentiation,survival, and the function of nerve cells. But there has been no easyway to scre...

Research on Worms Yields Clues on Aging

...n independent mechanism, according toKornfeld."Our experiments show there is an important connection between neuralfunction and longevity," Kornfeld says. "We're continuing this line ofresearch to identify the precise functions of the nervous system thatcause the worms to live longer."Because the researchers fou...

“Nano-scissors?laser shows precise surgical capability

... basicevolutionary form, opening the door to other experiments on genetic andmolecular factors that determine whether damaged nerve cells regrow.Ben-Yakar developed the femtosecond laser surgery technique using thelaboratories and equipment of Dr. Robert Byer, a Stanford Universityprofessor, while doing post-doc...

Breakthrough Microarray-based Technology for the Study of Cancer

...esearchInstitute. "Agilent has now taken array-CGH experiments into a newrealm of resolution, sensitivity, and reproducibility that allowsreliable detection of alterations at the scale of individual genes andeven introns and exons. This advancement, along with the possibility itprovides to correlate genomic copy...

Improved Outcomes Releases GeneLinker(TM) Gold and Platinum Version 4.6

...pectrum data to allow exported p-values from ANOVA experiments to bere-imported, enabling novel visualization of ...very rate. This allows exported p-values fromANOVA experiments to be re-imported, enabling novel visualization ofchannels that best distinguish between different c...

An HIV Protein Plays a Surprising Role in Gene Activation

... Green and colleagues confirmed this hypothesis in experiments showing that Tat-driven transcription proceeded as...ly linked to TBP in mammalian cells. Because their experiments analyzed only transcription complex assembly, the authors are careful to note that Tat may well stim...

Needling Chromosomes Reveals Cell Division Secret

...teredthe delicate technique and performed numerous experiments pulling thechromatids apart at different points al...gth and atdifferent times during cell division.The experiments revealed that the chromatids are attached to oneanother, but that they initially separate at their c...

Purdue proves concept of using nano-materials for drug discovery

...he chips could dramatically increase the number of experiments that are possible with a small amount of protein. "It's been very hard to study these proteins because they are difficult to produce in large quantities," Lee said. "The devices we have created offer the promise of making chips capable of running th...

Vital step in cellular migration described by UCSD medical researchers

...l, to maintain directional movement. In laboratory experiments with human and animal cells, the UCSD team discovered that the alpha4 integrin recruits enzymes that block Rac activity only at the rear of a crawling cell. The scientists noted that alpha4 integrins are widely expressed in neural crest cells, immun...

Taking Aim With Nanoparticle PEBBLEs

...ated and how they respond to treatment. In recent experiments with a small number of rats that had a type of brain cancer called 9L-gliosarcoma, PEBBLE-based treatment significantly increased survival time. People who get that type of cancer usually live less than four months without treatment; rats die within ...

Elephants imitate truck noises, other animals

... signals with shared associations. Recent playback experiments conducted by Karen McComb of Sussex University have shown that elephants can remember the calls of a large number of other elephants. The new findings suggest that elephants, like parrots, bats, and dolphins, may use vocal learning to develop new com...

Placenta Is A Rich Source Of Blood Stem Cells

...organ that nurtures the baby in utero. Meticulous experiments in mice revealed that the placenta harbors a large supply of hematopoietic (blood-forming) stem cells. These cells, which appear very early in development, are able to generate more blood stem cells and can give rise to a complete blood system when t...

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