UF scientist finds unexpected link between cat and human AIDS viruses
...use feline and human AIDS: Cats vaccinated with an experimental strain of the human AIDS virus appear to be at lea...eated even more effectively using some form of the experimental human vaccine. Researcher Janet Yamamoto, a professor at UF's College of Veterinary Medicine, also...Dendritic cells offer new therapeutic target for drugs to treat MS and other autoimmune disease
... his Hopkins colleague Katherine Whartenby used an experimental compound called CEP-701, already known to block actions of the growth-promoting FLT3 gene, on human dendritic cells and in mice engineered to mimic multiple sclerosis, a disease that causes T-cells to destroy the myelin protein sheath around nerves i...New cell transplantation technique restores insulin production in diabetics
...taneous islet cell transplantation is currently an experimental procedure, the sandwich closure is a safe method that prevents many of the complications common to previous techniques used to transplant islet cells. Thirty days after the procedure, all 13 patients were producing insulin without requiring supplemen...Scientists develop nanotech-laser treatment that kills cancer cells without harming healthy tissue
...which soon heated up and died. "Folate is just an experimental model that we used," Dai says. "In reality, there are more interesting ways we can do this. For example, we can attach an antibody to a carbon nanotube to target a particular kind of cancer cell." One example is lymphoma, or cancer of the lymphatic ...Kenya halts first field trials of GM maize
...illus thuringiensis, have already been grown under experimental conditions in IRMA's US$12 million 'biosafety' greenhouse ( see $12 million greenhouse signals Kenyan GM commitment ). When the first IRMA maize seeds were sown outside in May, Kenya became the first African country after South Africa to plant GM m...Swimming with dolphins can alleviate depression
... or moderate depression. Half were assigned to the experimental group and half to the control group. Over a two-week period, participants in the experimental group swam and snorkelled in the water with dolphins for one hour a day. Participants in the control......vailing notion of columnar function by devising an experimental method that used glass microelectrodes to "listen" to two neurons at a time. They used rats, whose brain organization mirrors that of a human, and dissected tiny vertical slices to preserve the circuitry. With fine glass pipettes, they recorded tiny ...Sudden change in social status triggers genetic response in male fish, study finds
...d night-vision goggles and kept close watch on the experimental fish tanks. She soon discovered that dominant males undergo a temporary change in the dark--their bright color turns pale, and their eyebar fades. "But when the lights come on, the dominant male slowly reactivates," she says. "He goes through a warm-...New vaccine platform may fight infections with causes from influenza to bioterrorism
...ents helped identify the two key components of the experimental DNA vaccine, so called because it has only the molecular signatures of these constructs: the molecule used by activated CD4+ T cells to signal production of antibodies, and importantly, the specific fragment of pneumocystis that receptors on these an......b and biochemist J?Tittor thus designed additional experimental studies which showed that Natronomonas pharaonis does indeed have a functioning respiratory chain, which amazingly, and in contrast to other organisms that grow in alkaline conditions, functions with a "normal" proton. The Max Planck researchers coul...Oysters: The natural way to protect our shores
...e. The authors evaluated the effectiveness of six experimental shell reefs on both low and high wave energy shorelines in coastal Louisiana. The areas chosen were conducive to oyster habitation, evidenced by the abundance of oyster shells in surrounding waters. Measuring erosion over a year, the authors found ...A new window into structural plasticity in the adult visual cortex
...n grow, retract, and sprout new additions--without experimental manipulations. It remains to be seen whether the structural plasticity seen here underlies observed functional reorganizations. Probing this question will depend on determining what kinds of structural changes might be expected, figuring out how to ...Getting an evolutionary handle on life after reproduction
...Michael Bryant, and Donna Holmes provide the first experimental confirmation that evolution works selectively on t...lifespan, the authors make a strong case for using experimental comparative analyses of other species to gain an evolutionary perspective on the human condition. ...Plant gene related to cancer treatment may foster new oncology drugs
...that PGP1, a P-glycoprotein from the commonly used experimental plant Arabidopsis, directly transports auxin out of plant cells and also out of yeast and mammalian cells. In the Plant Cell study, they found that other PGP proteins move auxin into cells. "Auxin molecules essentially are pulled through the cell me...Anti-cancer drugs may hold promise for premature aging disorder
...titutes of Health (NIH), has found that a class of experimental anti-cancer drugs also shows promise in laboratory studies for treating a fatal genetic disorder that causes premature aging. In a study published Monday in the online edition of the Proceedings of the National Academy of Sciences (PNAS), Brian Cape...Magnetic probe successfully tracks implanted cells in cancer patients
...inical trials, the research team switched from the experimental magnetic tags to formulations of iron oxide already approved for clinical use in Europe (as Endorem) and the United States (as Feridex). Because immature dendritic cells naturally take up materials around them, they simply absorbed, or ingested, the ...Polymer gel can block toxic leakage problem in gene therapy
...ter being injected into breast tumors implanted in experimental mice. That investigation showed that 10 times more of the viral particles were transported to other organs than were retained within the tumors. And most of the errant viruses ended up in the liver, where the gene therapy protein products could caus...Double trouble: Cells with duplicate genomes can trigger tumors
...s co-first authors. The research was performed in experimental animals, but such "double-value" cells are seen in a variety of early human cancers and in a precancerous condition called Barrett's esophagus. In addition to the extra chromosomes, the "double value" or "tetraploid" cells also duplicate a cell struc...Nanoparticles, nanoshells, nanotubes: How tiny specks may provide powerful tools against cancer
... body. But when nanoshells are injected into an experimental animal with cancer, they accumulate in the tumor; ...ser source was used to irradiate the tumors in the experimental group of mice. At the end of the study, 82 percent of the mice survived in the experimental group, b......entists have shown to cause damage to the brain in experimental stroke and brain injury. IL-1ra is currently used to manage rheumatoid arthritis but, as a long-term treatment, the cost is prohibitive. With stroke, the drug would have to be administered within the first few critical hours through an infusion over...