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Tag: "experimental" at biology news

Supercomputers to focus brains on AIDS dilemma

...mbining our computer simulations at SDSC and Merck experimental research, are giving real hope that the remarkable story of molecular dynamics simulations in helping discover HIV-1 protease inhibitors may be repeated with HIV-1 integrase inhibitors," said McCammon. "This could potentially save many lives in the f...

Man-made wetland's effectiveness similar to natural marsh

...sources. They wanted to know if the design of this experimental wetland would work. Apparently, it did. "It was a relatively simple, inexpensive way to create a wetland, and it worked," said Mitsch, who is a professor of natural resources at Ohio State. The wetland was constructed by bulldozing a series of basi...

Symbiotic bacteria protect hunting wasps from fungal infestation

...reads of their cocoons. The researchers found that experimental removal of the bacteria caused increased fungal infestations and increased larval mortality ?in fact, little larval survival ?suggesting that the bacteria produce antibiotics that work against pathogenic fungi. These findings broaden our understandin...

Successful Test Of Single Molecule Switch Opens The Door To Biomolecular Electronics

...?and in the process has developed a groundbreaking experimental technique that provides a “roadmap?for designing s...Nano Letters. Lindsay’s team reports achieving an experimental result that physicists have been trying to detect for a long time: negative differential resistance ...

Science study holds implications for gene therapy and stem cell biology

...topher Baum, MD, an adjunct associate professor of experimental hematology at Cincinnati Children's, is one of a f...olerate in gene therapy, just as in other forms of experimental medicine," Dr. Baum said. In 2003, Dr. Baum established a research team in the molecular and gene t...

To Stop Evolution: New Way Of Fighting Antibiotic Resistance Demonstrated By Scripps Scientists

...otics are effective, and they must be treated with experimental and potentially toxic drugs. Now some super bugs -- multiple drug-resistant bacteria -- are emerging as an even greater threat. Multiple drug-resistant TB is no longer susceptible to broad categories of antibiotics, such as rifampicin, isoniazid, an...

What the eye doesn't see

The first experimental evidence that birds can be deceived by camouflage in the same way that humans are deceived, is published today in Nature [3 March 2005]. The idea that bold contrasting colours help to break-up the body's outline was rapidly adopted by many armies as...

NHGRI targets 12 more organisms for genome sequencing

...he genome of the pea aphid, used extensively as an experimental model, will be a valuable comparison with other insects, such as the closely related insect, Rhodnius prolixus. Another insect, the parasitoid wasp Nasonia vitripennis, is a natural enemy of houseflies, and its relatives are natural enemies of ticks...

Computational Tool Predicts How Drugs Work In Cells, Advancing Efforts To Design Better Medicines

.... The team used a combination of computational and experimental methods to build and verify their tool, first using a reverse-engineering approach to decipher the multitude of regulatory networks operating among genes in a simple organism, then testing the ability of the resulting network models to predict gene a...

New miniaturised chip dramatically reduces time taken for DNA analysis

...ady takes place in laboratories, but until now the experimental measures needed were not suitable for in situ analysis. By using the new sensors developed by UAB scientists, the time taken to identify the source of infection for Legionella would decrease from two days, as is currently the case using organic produ...

Tamoxifen-like drug suggests new ways to selectively block estrogen

The ability of an experimental drug known as GW5638 to change the shape of the estrogen receptor is helping researchers understand why drugs like tamoxifen and raloxifene behave the way they do, simulating the effects of estrogen in some tissues and blocking it in others. The find...

Critical step traced in anthrax infection

...translocation of the toxin proteins. These recent experimental results extend and explain a 1999 discovery by the Collier lab identifying a set of mutations in protective antigen that prevent translocation, some of which represented a new type of antitoxin that may be useful in anthrax treatment. In the recent ...

Random gene expression may drive HIV into hiding

...e University of California, Berkeley. By combining experimental and computational studies of HIV's replication cyc... best explanation, they conducted a large array of experimental controls to discount other hypotheses and then created computer programs to model what would happen ...

Mosaic mouse technique offers a powerful new tool to study diseases and genetics

...mouse geneticists "one step closer to the enviable experimental facility available to invertebrate geneticists." There are "many potential applications of this powerful approach," Anthony and Heintz wrote, including the "opportunity for in-depth studies of molecular mechanisms that underlie the dynamic propertie...

Mapping neuron connections in the brain

...o either highly simplified formulations or tedious experimental methods requiring precise three-dimensional reconstructions of neuron arbors, tremendously branched structures formed by neurons. Part of the difficulty in mapping lies in the complex structure of arbors. Amirikian has improved on past methods by de...

Researchers develop promising new gene network analysis method

...s. After applying both statistical methods to the experimental data, the team found that the correlation method was a more effective analytical tool. The method was sensitive enough to capture gene network changes after tamoxifen treatment, producing a list of 130 genes significantly altered by c-Myc activation....

Bioinformatics reveals new gene regulation system

...s can uncover cell systems that might have escaped experimental detection, he suggested. "By comparing hundreds of genomes, you can see patterns that are not seen when looking at just a couple of them." ...

When it comes to cell entry, being average has its advantages

...ompared the implications of their theory to actual experimental observations with cells, they found broad agreement. "The theory is fundamentally sound ?a significant outcome," Freund said. ...

Brown-Harvard team solves mobile DNA's surgical sleight-of-hand

...t was gratifying to see that two totally different experimental approaches give the same picture," Radman-Livaja said. "It means we have a very solid foundation for the next step forward in understanding this fascinating process." ...

Motor transport in bio-nano systems

...etical results are in agreement with the available experimental data, both for biomimetic systems and for biological cells. The theory has been extended to more complex systems such as two-way traffic of two motor species that move along the same filament but in opposite directions. The latter system exhibits a g...

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