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Tag: "experimental" at biology news

Chemists identify key gene in development of type 1 diabetes

...insulin. Al-Abed and his associates hope that the experimental compound can one day be developed into a long-acting oral drug that could be taken by prediabetic people to achieve lasting protection, perhaps a lifetime. But such a drug would take years to develop and test, the researchers caution. Likewise, effec...

Towards precise classification of cancers based on robust gene functional expression profiles

...insulin. Al-Abed and his associates hope that the experimental compound can one day be developed into a long-acting oral drug that could be taken by prediabetic people to achieve lasting protection, perhaps a lifetime. But such a drug would take years to develop and test, the researchers caution. Likewise, effec...

New Insights Into HIV Immunity Suggest Alternative Approach to Vaccines

...n and the biology of autoimmunity after work on an experimental outer coat vaccine failed to produce broadly neutr... animals. "Recently, we spent two years making an experimental outer coat vaccine candidate that had the correct areas on the outer coat for the good broadly neutr...

Ophthalmologists implant five patients with artificial silicon retina microchip

...spond to this new treatment since this is still an experimental trial. If this study and future studies show safety and efficacy of the chip and it's approved by the FDA, it could be as soon as three to five years that this technology would be available to others." Surgical Information The ASR chip contains appr...

Rats infected as newborns grew up vulnerable to memory problems during an immune challenge

...st memory, each rat was allowed to explore a novel experimental chamber for several minutes on the first day. On t...4 hours, the researchers again put each rat in the experimental chamber and recorded whether the rats froze -- was immobilized by fear -- or stayed active. All gro...

Programmable cells: Engineer turns bacteria into living computers

...behavior of the organisms. So far, said Weiss, the experimental results have matched the computer models fairly closely, but the goal is to have a mathematically exact description of how each component works. "One of the nice things about synthetic biology is that because we built the network from scratch, we sh...

Fleshing out the genome

.... They offer a powerful new method that integrates experimental and computational analyses to ascribe function to ...hypothetical proteins. All told, computational and experimental evidence provided functional information for 256 more genes, or 48 percent, but they could confident...

McGill researchers shed light on formation of carcinogen in food

...us. Although furans have been linked to cancer in experimental animals, there is no direct evidence that furans are human carcinogens. "Even so," says Dr. Yaylayan, "food companies and government agencies are keeping a close eye on the situation. It's important to know exactly what chemicals are present in food...

Computational Method Speeds Mapping of Cell Signaling Networks

...ow inside cells is a difficult task using standard experimental methods. Multidisciplinary research teams are work...technique--a combined approach of state-of-the-art experimental and computational methods that "fit like a hand in a glove,"--by mapping a well-studied signaling ne...

Researchers rein in regulatory RNAs

...erformed one of the most comprehensive genome-wide experimental analyses of sense-antisense transcripts to date. Their findings are published in the April issue of the journal Genome Research. Sense-antisense transcripts, or SATs, are pairs of RNA molecules generated from opposite DNA strands at the same locus. ...

Researchers make gains in understanding antibiotic resistance

...dications. The findings are already leading to new experimental antibiotics that are being engineered to circumvent resistance, which is a major worldwide health problem. Led by Thomas A. Steitz, a Howard Hughes Medical Institute investigator at Yale University, and Peter B. Moore, a professor of chemistry at Ya...

Global analysis of membrane proteins

...hemistry and Biophysics, has used a combination of experimental techniques and theoretical structure prediction methods to produce simple structural models for some 600 membrane proteins from Escherichia coli. They have also identified those membrane proteins that the bacterium can manufacture in large amounts, a...

Roots Engage in Underground Chemical Warfare

...ins a fascinating problem. The simple, yet elegant experimental approaches used by this team uncovered a critical aspect of the battle that occurs between plants and microbes. ...

Agilent Technologies releases probe sequence, annotation information for all its commercial gene expression microarrays

...nformation is expected to improve cross-laboratory experimental research and cross-platform data comparison. "Ful...njunction with the extensive release of microarray experimental data into the public domain by the National Toxicology Program. Icoria Inc., under its contract with...

Virus-host interactions at sea effect global photosynthesis

...nformation is expected to improve cross-laboratory experimental research and cross-platform data comparison. "Ful...njunction with the extensive release of microarray experimental data into the public domain by the National Toxicology Program. Icoria Inc., under its contract with...

B-15A collides with Antarctic ice tongue

...nformation is expected to improve cross-laboratory experimental research and cross-platform data comparison. "Ful...njunction with the extensive release of microarray experimental data into the public domain by the National Toxicology Program. Icoria Inc., under its contract with...

NIAID begins clinical trial of West Nile virus vaccine

A small trial testing the safety of an experimental vaccine targeting West Nile virus (WNV) opened tod... and Prevention (CDC). Vical also manufactures the experimental vaccine. "Although the prevalence of West Nile virus disease fluctuates seasonally and regionally, ...

Doctors closer to using gene analysis to help trauma patients

...sly ill has worked consistently in a wide range of experimental clinical settings ?an important hurdle to overcome.... The next step is for scientists to continue the experimental procedures in larger multicenter trials, following hundreds of patients over time to describe the mo...

Measuring Enzymes At End Of Cancer Pathway Predicts Outcome Of Tarceva, Taxol

...t for effective use of Tarceva," he says. The only experimental predictive test currently available is whether lung cancer cells have a mutation in their epidermal growth factor receptor (EGFR), but that does not predict response to the targeted therapy in other forms of cancer, Ueno says. "We find here that as ...

Secret of smallpox's success may lead to bioterror cure

...liminary, several strains look promising. Jacobs' experimental results verify that the de-cloaked viruses not only do not cause disease, but improve disease resistance when they are present. When a mouse has been exposed to a lethal vaccinia virus and then is vaccinated with a very low dose of the mutant virus ?...

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