Mice lacking key immune component still control chronic viral infections
...ecause the genetically modified mice used in their experiment lacked the genes that contain instructions for making MHC Class I molecules, Virgin and his colleagues expected to see little response from CD8 T cells when they injected the mice with herpes virus. Initially, that was exactly what they found. "Thi...New MRI technique quickly builds 3-D images of knees
...e, a lot of time was spent either prepping for the experiment or returning it to the steady state so that you could do the next experiment," Block says. "What we're doing now is capable of a study that you can visualize in any plane in about the same time as people are doing one plane." For example, when imag...How plants avoid feeling the burn
...the heart of the problem, Fisher had to attempt an experiment that had never been done before for any biomolecul...ant system. One of the greatest challenges of the experiment came down to the human endurance of taking thousands of measurements over an intense, six month peri...Microscopic passengers to hitch ride on space shuttle
...stronauts' space environment. The results of this experiment will help NASA scientists evaluate the risks to as...e at Arizona State University, Tempe. "Our Microbe experiment will be the first to investigate the effects of spaceflight on the disease-causing potential and gen...Mechanism identified for promising neurological drug
...ARP-1 inhibitors. This perception led to "a simple experiment ?putting cells in a dish, doing things to the cell...ys Alano. Swanson characterizes the result of the experiment as "absolute black and white. Minocycline, at extremely low concentrations, inhibits PARP-1 in cell ...Cigarette smoke blocks cell repair mechanism, University of Florida study shows
...densate contains more than one compound, so the UF experiment is more similar to the way any human being would be exposed to the carcinogens. It mimics the human situation more closely."...UF scientists restore sight to chickens with blinding disease
...y but who participated in a landmark gene transfer experiment five years ago that restored vision to blind Briard dogs. "This is proof of concept using a unique vector, animal model and approach. One would hope this could happen in a human." Semple-Rowland, a College of Medicine faculty member, has worked sinc...Successful transplantation from pig embryos to mice
...d human immune cells injected into them. From this experiment they learned that tissues taken at 42 days (within...reduced immune response. Next, the team tried the experiment on mice with fully functioning immune systems, but destroyed the insulin-producing cells in their pa...Ready, set, mutate?and may the best microbe win
...r. Rice University biologists, using an ingenious experiment that forced bacteria to compete in a head-to-head ...ow it aided in metabolic regulation. The fermentor experiment was repeated and the same mutations ?and no others ?were observed to develop again. Three of the six...Surprise finding for stretched DNA
... this makes from an intuitive standpoint, a recent experiment proved it not to be the case. Researchers with the U.S. Department of Energy's Lawrence Berkeley National Laboratory (Berkeley Lab) and the University of California at Berkeley used a combination of microscopic beads and magnetic tweezers to observ...Carnegie Mellon researchers discover key deficiencies in brains of people with autism
... to strategize and plan several moves ahead. The experiment confirmed the authors' previous findings that people with autism suffer from a lack of synchronization among brain regions, which helps to explain why some people with autism have normal or even superior skills in some areas, while many other types o...Speeding the search for elusive chromosomal errors
...rized genetic diseases. In a blinded analysis, the experiment found the correct location of the abnormal regions. In the second part of the study, the researchers studied samples from 10 patients with multiple congenital anomalies, all of whom had previously normal results from karyotype and subtelomeric testi...New research promising for improving brain cell survival after brain injury
...BP5 in stressedneurons and this proof-of-principle experiment showed that BP5 can prevent neurons from undergoing cell death. "BP5 works by using the cell's waste disposal system to flush away toxic and damaged proteins produced after injury, which appears to tip the balance towards nerve cell survival, inst...Loosen up, DNA: Leukemia gene changes genetic packaging
...partment of Biomedical Genetics, devised a complex experiment involving fruit flies. Researchers created flies with normal amounts of the signaling system and compared them to mutant flies with increased or decreased JAK/STAT signaling. They moved the location of the "red-eye reporter gene" around, sometimes in...AIDS vaccine research offers new insights on survival
... T-cell counts dropped. But instead of ending the experiment at this point -- assuming that the vaccine conferred protection for only 100 days -- Letvin and his VRC colleagues decided to follow the monkeys for an additional 750 days, a total of 850 days or nearly three years. "We found that the vaccinated mon...Female birds boost up their eggs when hearing sexy song
...ain male offspring in natural environments, in the experiment there was no difference in brood sex ratio between the different songs played to the females, which suggests different levels of female control. Male birdsong has long been known to attract females and influence mate choice decisions and even induce ...Just like us, social stress prompts hamsters to overeat, gain weight
... were placed in the situation only once during the experiment did not eat more or gain weight compared to a control group. In addition, the intruder hamsters that were placed in the cage intermittently (at unpredictable times) showed comparable weight and fat gain compared to those placed in a foreign cage cons...Patients to benefit from novel technology revolutionizing high-speed molecular imaging
...dical Center will be among the first four sites to experiment with the imaging camera, said Patton, who indicated that the imaging device is investigational, with Food and Drug Administration submission expected over next few months. ...Thermal imaging shatters arousal gender gap myth
...tistically negligible difference. "In any experiment on sexual arousal done in a laboratory, there is some distraction," said Binik. "But compared to previous techniques involving invasive measures or electrodes, this is minimally invasive and the same measurements are used for men and women, which mak...Gene transfer using mutant form of good cholesterol cuts vascular plaque and inflammation
...ination," Shah said. "We used three methods in our experiment and all three methods demonstrated that macrophages containing the apo A-I Milano gene were more effective in effluxing cholesterol out of them, compared to those carrying the wild type apo A-I gene. Therefore, we concluded, the greater beneficial ef...