Roche clinical trial registry and results database launched
...e selected CenterWatch, a company with a wealth of experience in the area of data management and the publication of clinical trial information. So for the first time ever, there is now a global and publicly accessible database, containing comprehensive information about Roche’s clinical trials? Roche expects t...FDA Works To Speed The Advent Of New, More Effective Personalized Medicines
...n making, will help FDA and industry gain valuable experience as this new field continues to evolve. FDA believes this approach will save time and resources and eliminate possible delays in the application review process because parties will be able to familiarize themselves with novel pharmacogenomic approach...What's really making you sick? Plant pathologists offer the science behind Sick Building Syndrome
... refers to a situation in which building occupants experience health problems while inside a particular building. Human health issues typically associated with SBS range from allergy attacks and asthma to more complex medical problems involving exposure to toxins. Mold is a common cause of SBS, said Mani Skari...Africa to take it on chin again with climate change
...c drought until rains returned in the 1990s, could experience wetter monsoons for decades to come. However, drought across southern Africa is projected to intensify further. Oceanic warming consistent with an increase in greenhouse gases appears to be a factor in these expected 21st-century changes to Africa's ...NIAID begins clinical trial of West Nile virus vaccine
...from mother to child during pregnancy. Most people experience no symptoms or only mild symptoms, such as fever, ...l Trials Core Laboratory. Adds Dr. Graham, "In our experience in clinical trials, DNA vaccines generally cause few side effects, making them a promising alternati...Advancements In Genomics Foster Deep Sea Discoveries
...hin the membrane that gets squeezed when the cells experience higher pressure, and that triggers a signal transduction event that activates the expression of genes that help the cells to adapt to the increased pressure,?said Bartlett. The scientists found other tantalizing discoveries in Photobacterium profundu...Doctors closer to using gene analysis to help trauma patients
...te scientists. “The vast majority of patients who experience severe trauma or burn injuries actually do well,?said Lyle Moldawer, a surgery professor in UF’s College of Medicine. “They’re resuscitated at the scene, taken to the hospital, have an uneventful recovery and they’re discharged. But there’s a certain...The lopsided brain: Attention bias is shared by humans and birds
...uffered injury to the brain's right hemisphere can experience a much more severe bias in their spatial attention--spatial hemineglect--in which the entire left side of the visual world seems nonexistent as the brain performs spatial tasks. In a classic example, a patient asked to draw a daisy can only manage to...Researchers make surprise discovery that some neurons can transmit three signals at once
...ing is fully developed. So, perhaps early auditory experience provides the signals that stop the cells from releasing glutamate, which is a prerequisite for correctly processing auditory information. "It will be interesting to find out whether abnormal hearing, such as partial deafness or hearing dominated by ...The circadian clock: Understanding nature's timepiece
...shifts are constantly struggling to adapt and they experience well-documented health problems as a result. For example, one study found that nurses who work nights or rotating shifts are at greater risk for developing breast cancer than their counterparts on regular day shifts. "If your sleep schedule is const...Finding hidden invaders in a Hawaiian rain forest
...natures, Myrica faya. This is the first time in my experience that remote sensing has detected an understory species, kahili ginger, one of the most disruptive weeds in Hawaiian rain forests." Asner commented on the expanded effort with the multi-institutional team: "Because Hawaii contains so many different t...New strategies to reduce hospital-aquired infections
...ing the problem and that they can also look to the experience and success in Europe to ensure that patients are protected from dangerous waterborne pathogens. Health and government agencies continue to stress the need for more stringent approaches to dealing with nosocomial infections, such as the new infectio...Distributed Basic Local Alignment Search Toolkit (W.ND-BLAST)
...ing the problem and that they can also look to the experience and success in Europe to ensure that patients are protected from dangerous waterborne pathogens. Health and government agencies continue to stress the need for more stringent approaches to dealing with nosocomial infections, such as the new infectio...Making Sure Sacred Sheep Don't Become Extinct
...rst animal sample in 2000. "It's really a learning experience for us; it's a step beyond the biology, one in which we have to consider social implications," he explains. To develop the collection, animal physiologist Phil Purdy, also of the Fort Collins center, traveled to the Navajo Nation to collect germplas...Sugar beet virus mutation requires Texas touch
... the viruses, and by default, I ended up with more experience than anyone else," he said. Strong genetic resistance to rhizomania was bred into sugar beet varieties and until 2002, that was effective, Rush said. But with only one gene selected for resistance, the plant virus mutated and overcame the resistant g...Asymptomatic HIV babies could use earlier treatment
...ikely to receive triple therapy and less likely to experience AIDS-related complications or death. In fact, none of the 23 children who received triple therapy died or developed AIDS before their third birthday. In contrast, about 55 percent of the children in the first two groups died of AIDS. When the researc...New miniaturised chip dramatically reduces time taken for DNA analysis
...hemistry, developed the new sensors based on their experience in research with electrochemical sensors. These can identify a substance by chemically interacting with it and converting this interaction into an electrical current that they measure. To detect DNA, the new miniaturised electrochemical genosensors ...NCI Researchers Confirm the Effectiveness of Immunotherapy Approach to Treating Melanoma
...e were three (9 percent) patients who continued to experience complete disappearance of tumors. This result is particularly significant because these patients had not responded to standard treatments or chemotherapies used in treating patients with melanoma. Thirteen patients relapsed after positive response t...Bumblebees copy one another when contending with unfamiliar flowers
...herefore been thought to rely mainly on individual experience when seeking out rewarding flowers. The role of other bees in these decisions has been considered only in the context of deterrence because the small scent marks that foragers leave after emptying flowers dissuade others from visiting. In the new st...Drug Offers Alternative to Surgical Treatment After Miscarriage
... than vacuum aspiration. Roughly one in four women experience miscarriage, so the availability of a non-surgical treatment may provide an effective alternative for many women, he added. “Misoprostol is inexpensive and does not need to be refrigerated,?Dr. Zhang said. “It could provide treatment for miscarriage...