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Tag: "existence" at biology news

Spleen may be source of versatile stem cells

...velopment of mammals.The finding both supports the existence of these splenic stem cells andalso suggests they may be able to produce an even greater variety oftissues. The report appears in the January 19 issue of SAGE KE , an online resource on the science of aging from the publishers of the journal Science...

Bound for destruction: Ubiquitination protects against improper Notch signaling

...s an important molecular signaling mechanism whose existence has beenknown, or at least hinted at, for nearly a century since theidentification of a mutant strain of Drosophila fruit flies with“notched?wings in Thomas Hunt Morgan’s lab in 1910. Later studiesrevealed that the Notch gene encodes a receptor prote...

Papers of DNA Pioneer and Nobel Laureate Francis Crick Added to National Library of Medicine’s Profiles in Science Web Site

...f DNA, and Crick’s unpublished note predicting the existence of transfer ribonucleic acid. Profiles in Science was launched September 1998 by the National Library of Medicine. The Library, the world’s largest library of the health sciences, is a component of the National Institutes of Health, U.S. Department ...

Advances in the characterisation of the oyster mushroom genes

...fferent cellobiohydrolases, thus demonstrating the existence of a multigenic family responsible for the said enzymatic activity. Also, using such genomic sequences as a probe, it has been possible to detect what are the conditions under which the expression of each one of the genes is produced. This has enable...

Single stem cells from bone heal a broken heart

... colleagues from Tufts University now document the existence of a previously unrecognized subset of human bone marrow–derived stem cells with therapeutic potency for myocardial tissue regeneration following myocardial infarction. In their study, featured in the February 1 issue of the Journal of Clinical Inve...

Researchers rein in regulatory RNAs

...oaches; very few have experimentally validated the existence of overlapping RNA molecules in vivo. With this in mind, Dr. Hidenori Kiyosawa, the lead author on the paper, set out to confirm the presence of SATs in a variety of mouse tissue types and cell cultures, as well as to identify common characteristics ...

Researchers discover underwater volcano

...igel. Scientists were tipped off to the volcano's existence when they profiled the seafloor of the Vailulu'u crater using multibeam mapping. Existing maps of the seafloor in the area gave little indication that this volcano existed. When sound beams were directed into the crater this time, they measured an un...

Supercomputers to focus brains on AIDS dilemma

...e catalytic domain and an inhibitor pointed to the existence of only one site where inhibitors could bind. These studies indicated a single format for small inhibitors of integrase to bind at the catalytic site, typically with a cyclic moiety, or "wing," to the "west" of the active center. Around this same ti...

Scientists analyze chromosomes 2 and 4

...articular proteins. The new analysis confirmed the existence of 1,346 protein-coding genes on chromosome 2 and 796 protein-coding genes on chromosome 4. As part of their examination of chromosome 4, the researchers found what are believed to be the largest "gene deserts" yet discovered in the human genome seq...

Nanobacteria in clouds could spread disease, scientists claim

...ment and that their evidence is compelling for the existence of these nano-organisms, even in the stratosphere. In humans, nanobacteria have now been identified on four continents, they add. Dr Sommer and Professor Wickramasinghe further suggest that nanobacteria's involvement in several serious diseases such...

Ebola virus: from wildlife to dogs

... several species of non-human primate suggests the existence within this fauna of different degrees of susceptibility to Ebola and, possibly, of strains of various levels of virulence. However, most large primates, once infected, soon die of the disease. Their bodies then become a potential source of contamina...

Second messenger NAADP shows fast, dose-related impact on satiety cycle

... cell surface, the cholecystokinin-A receptor. The existence of the cholecystokinin-A receptor in the brain strongly implies a possible role of NAADP in cholecystokinin-induced satiety," Yamasaki said. Methods, results and conclusions The team worked on the theory that NAAPD mobilizes Ca2+ from lysome-relate...

Life detection instrument passes key test on road to Mars

...rtian surface and possible signs of water, but the existence of liquid water was speculative, and people thought I was crazy to be working on an experiment to detect life on Mars," Skelley said. "I feel vindicated now, thanks to the work of NASA and others that shows there used to be running liquid water on th...

Vitamin A's paradoxical role in influencing symmetry during embryonic development revealed

..."holy grail" puzzles of developmental biology: the existence of a mechanism that insures that the exterior of our bodies is symmetrical while inner organs are arranged asymmetrically. In research with zebra fish, as a model for human biology, Juan-Carlos Belmonte and his Salk Institute colleagues found that r...

Stem cells in bone marrow replenish mouse ovaries

...the egg and sperm, the team shows evidence for the existence of germ cell progenitors, putative stem cells, in mouse bone marrow and blood. In addition, the researchers also found these markers in human bone marrow and blood. Remarkably, the researchers found that bone marrow or blood cell transplants appear ...

Program finds lost genes in nematode genome

... his colleagues have developed predictions for the existence of a whopping 1119 more genes. Michael Brent, Ph.D., Washington University professor of computer science and engineering, used his unique software, TWINSCAN, on the genome of Caenorhabditis elegans (C. elegans). The genome of another nematode C. bri...

Mechanism for the captation of nutrients in plants- unknown to date

...of this research is that, while not discarding the existence of specific transporters in plasma membranes, thei...sis. Thus, the experiments carried out showed the existence of processes independent of nutrient captation: a saccharose penetration process independent of "end...

Scripps research scientists identify infertility molecule

...technique of in vitro fertilization). Despite the existence of these therapies, however, the molecular mechanisms that govern female infertility are not completely understood. In fact, the cause of infertility is not always easy to diagnose. The American Society for Reproductive Medicine estimates that the ca...

Improving the potential of cancer vaccines

...'s own tissues. His group previously reported the existence of tumor-specific Treg cells at tumor sites. "Thus, the tumor cells use these Treg cells to protect themselves," said Wang. "In fact, tumor cells can actively recruit and activate them to turn on their immune suppressive function." One way to stop t...

Woods Hole Research Center plans controlled burn in Amazon rainforest

...learn whether recurring fire may threaten the very existence of the forest." Repeated burning of transition forests in the Amazon could cause their eventual replacement by fire-prone scrub vegetation through a process call "savannization." This is the second phase of this work, the world's largest tropical fi...

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