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Tag: "excessive" at biology news

Longer treatment benefits sleep apnea patients

...tients were evaluated for daytime symptoms such as excessive daytime sleepiness using two widely accepted assessment tools, and for daytime functioning using a standardized test before treatment and after three months of CPAP therapy. The findings suggest that most patients should use CPAP for at least 7.5 ho...

Runners -- Let thirst be your guide

...not going to be at risk of either dehydration from excessive sweat losses or EAH from excessive fluid ingestion.”...

Focused ultrasound relieves fibroid symptoms in women

...tic uterine fibroids. Fibroid symptoms can include excessive menstrual bleeding, enlarged uterine size, frequent urination, pelvic pressure or pain and infertility. According to the National Women’s Health Information Center, fibroids are the primary reason for surgical removal of the uterus, accounting fo...

First confirmed common genetic risk factors for breast cancer

...nce or exposure to an environmental toxin, such as excessive UV sunlight. However, BRCA-1, BRCA-2 and the other previously identified breast cancer susceptibility genes are mutated in a relatively small percentage of women. "Risk mutations within these genes are so rare that only a very small number of brea...

Double the death rate from cirrhosis for 'blue collar' men

... Professor Najman said reducing tobacco use and excessive alcohol consumption among the most socioeconomically disadvantaged should be an urgent national priority....

Gene found for rare disorder may reveal new pathway in mental retardation

... that join together, long eyelashes, thin lips and excessive body hair. "In many of these patients, an experienced clinician might recognize their more subtle facial features as suggestive of CdLS, but for the most part, they would only come to clinical attention for having mild to moderate mental retardat...

New compound prevents alcoholic behavior, relapse in animals by blocking stress response

...g the brain’s response to stress effectively stops excessive drinking and prevents relapse. The new, syntheti...consume more alcohol. Injections of MTIP prevented excessive drinking of alcohol in both cases and eliminated the rats?susceptibility to relapse under stress. Ye...

Misusing vitamin to foil drug test may be toxic; plus, it doesn't work

Taking excessive doses of a common vitamin in an attempt to defeat ...ailure, requiring a liver transplant, after taking excessive doses of niacin. Many Internet sites promote the misconception that niacin can be used to pass ur...

Microbes start immune response by sneaking inside cells

...fection. IL-1beta plays an important role, too, in excessive immune system activity in inflammatory diseases. The researchers report in the new paper how cryopyrin is activated to start the process. In experiments that exposed mouse immune cells called macrophages to bacteria, Thirumala-Devi Kanneganti, Ph...

Study uncovers a lethal secret of 1918 influenza virus

...nd moderate the host immune response." The same excessive immune reaction is characteristic of the deadly complications of H5N1 avian influenza, the strain of bird flu present in Asia and which has claimed nearly 150 human lives but has not yet shown a capacity to spread easily among people. "What we see...

Brain networks strengthened by closing ion channels

...at the level of ion channels." Arnsten said the excessive opening of HCN channels might underlie many lapses in higher cognitive function. Stress, for example, appears to flood PFC neurons with cAMP, which opens HCN channels, temporarily disconnects networks, and impairs higher cognitive abilities. There...

Growth hormone to boost athletic performance risks diabetes

...in 12 months, during which he had also experienced excessive urination, thirst, and appetite. He admitted to using anabolic steroids for 15 years and artificial growth hormone for the past three. He had also taken insulin, a year after starting on the growth hormone. This was done to counter the effects...

St. Jude announces breakthrough in eye cancer treatment

... activated in early-stage retinoblastoma, but that excessive levels of a molecule called MDMX blocked it from triggering apoptosis in more advanced tumors. Based on this discovery, the St. Jude team used a molecule called nutlin-3 to block MDMX in retinoblastoma cells in test tube studies as well as in mouse m...

German researchers develop first non-invasive test to measure skin aging

...erma, a poorly understood disease characterized by excessive deposits of collagen in the skin, and some chronic complications of graft-versus-host disease, which occur when the tissues of bone marrow transplant patients are attacked by immune cells coming from the donor. "Perhaps the technique could help monit...

Bones at the nanoscale

...s is why the brittle apatite remains shielded from excessive loads and does not break. The results also showed that the mineral crystallites are nonetheless very strong, ca-pable of carrying more than 2 ?3 times the fracture load of bulk apatite. Their small size preserves them from large cracks. This is th...

Study uncovers mutation responsible for Noonan Syndrome

... cells, where it was discovered that they promoted excessive activation of RAS and its downstream target, MAP kinase, the same pathway activated by PTPN11 mutations. "These results are the first example of activating mutations in an exchange factor in human disease," notes Neel, explaining that for families...

Gene therapy inhibits epilepsy in animals

...eptors are activated, they inhibit the repetitive, excessive firing of brain cells that characterizes a seizure. Seizures are thought to occur, at least in part, because of an imbalance between two types of neurotransmitters: the glutamate system, which stimulates neurons to fire, and the GABA system, which in...

Need to pull an all-nighter?

... new basis for the development of drugs to prevent excessive sleepiness or to promote sleep," says study co-author Paul Rosenberg, MD, PhD, a researcher in the Neurobiology Program at Children's Hospital Boston, and a physician in the Center for Pediatric Sleep Disorders at Children's and in the Sleep Disorder...

Holiday gluttony can spell disaster for undiagnosed diabetics

...sit a doctor for a diabetes test. Symptoms include excessive thirst or hunger, dramatic weight loss, fatigue, frequent urination or blurry vision. The holidays also are a perfect time to start getting healthy, she said, offering these tips: Set consistent meal times. Avoid fast food. At parties, cu...

76 percent of workers older than 60 years of age are overweight or obese

...e cardiovascular risk factors most associated with excessive weight and obesity. Furthermore, pre-hypertension, involving sustained blood pressure levels between 120-139 mmHg and 80-89 mmHg, affects 47% of active workers. He therefore concludes, according to his analysis, that there is a connection between met...

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