Anti-fungal drug stops blood vessel growth
...n antiangiogenesis drug. In mice induced to have excess blood vessel growth, treatment with itraconazole reduced blood vessel growth by 67 percent compared to placebo. “We were surprised, to say the least, that itraconazole popped up as a potential blocker of angiogenesis,?says Jun O. Liu, Ph.D., professo...Drug treatment improves learning in mice with Down syndrome symptoms, Stanford/Packard study shows
...his suggests that it’s not just the removal of the excess inhibition that allows learning to occur, but that we’re instead strengthening synapses through some type of long-lasting neuronal adaptation," said Garner. A key component of enduring neural change associated with memory is known as long-term pot...Magic Beans -- Anti-obesity soya could help prevent diabetes
...mpairment of insulin action, mainly as a result of excess abdominal adipose tissue - so loss of weight often improves glycaemic control,?says Dr Bender. Lynne Garton, a registered dietician and nutritionist and consultant to the Soya Protein Association, said: "Soy fits in well to a healthy balanced diet...Groundbreaking Canadian asthma study
... in which the airways in the lung become inflamed, excess airway mucus is produced, and airways narrow when muscles within the airway walls contract. During an asthmatic attack, in response to an asthma trigger such as an allergen or irritant, the airway smooth muscle may contract leading to airway narrowin...Major link in brain-obesity puzzle found
...tions in leptin and insulin signaling that lead to excess weight gain and Type 2 diabetes, respectively,?says Rui, an assistant professor of molecular and integrative physiology at U-M. “SH2B1 appears to play a key regulatory role in this system, through its direct influence on the processing of leptin and ...New research shows why too much memory may be a bad thing
...oles in distinct types of memory storage, and that excess neurogenesis can be detrimental to some memory processes." "We believe these findings have important implications for diverse disciplines ranging from medicine to artificial intelligence," said Dr. Malleret. "In medicine, these findings have signi...'Exercise pill' switches on gene that tells cells to burn fat
...t of exercise, some because of medical problems or excess weight that makes exercise difficult. Having acces...e exercised, and increase the burning of energy or excess fat in the body. And that would result in less fatty tissue, lower amounts of fat circulating in th......eghem's new control system less energy is lost and excess heat is reused. This means that sustainable energy can be used to control the climate in the greenhouse efficiently. Control system Van Ooteghem has developed a control system that maintains the correct climate in the greenhouse, whatever t...Researchers to study why dead zone returned to Lake Erie
...ee main culprits and the relationships among them: excess phosphorous; zebra mussels; and global warming. Of the three causes, nitrogen from farm runoff and treatment plants is the most well known. The nitrogen in fertilizer causes algae blooms that sink to the bottom and are consumed by bacteria, which ...Neuron cell stickiness may hold key to evolution of the human brain
... then identified 992 elements with a significant excess of human-specific nucleotide substitutions relativ...e only biological process displaying a significant excess of accelerated CNSs. To determine whether this pattern of accelerated CNSs was repeated in other ani...Why don't all moles progress to melanoma?
...ows the protein production process and gets rid of excess incoming amino acids, giving the ER a chance to catch up. If that doesn't work, the UPR causes the cell to destroy itself in a process called apoptosis. "Traditionally, the ER's role was considered to be limited to protein folding or protein modifi...Mutant gene causes severe kidney disease in infants
...h a network of tiny capillaries in the glomerulus, excess water, salts and toxic molecules are removed and flushed out in urine, while important blood proteins like albumin are retained in the bloodstream. If the kidney's filtering units don't work properly, nephrotic syndrome develops. Proteins leaking out...Scientists discover way to block growth of prostate cancer cells
...tive stress, a condition in which cells produce an excess of oxygen-free radicals, which are known to play a key role in cell signalling and prostate cancer development. "These results demonstrate that polyamine oxidation is one of the major causes of androgen-induced oxidative stress in prostate cancer ...Studies find general mechanism of cellular aging
...r 'knocked out") or genetically altered to have an excess of the protein to a degree seen in aging. Accord... as if they were younger animals." In mice with an excess of p16INK4a, "islet cells aged prematurely; they stopped dividing early." "This suggests that if we...Malaria may fuel spread of HIV in sub-Saharan Africa
...ed to HIV," he said. That translates into 8,500 excess HIV infections and 980,000 excess malaria episodes since 1980 in a town with an adult population of about 200,000, the researchers sai...Transmission of antibiotic-resistant bacteria linked to previous intensive care unit room occupants
...RE and 3.9 percent vs. 2.9 percent for MRSA). The excess risk associated with an infected prior occupant accounted for 5.1 percent of all new cases of MRSA and 6.8 percent of all new cases of VRE. This additional risk occurred despite the fact that the room cleaning procedures of the hospital in the stu...New sunscreen ingredient to heal sunburn and help prevent skin cancer
...d chelators which were strong enough to export the excess iron out of cells, but that would not have an adverse effect on other essential cellular processes. After three years of research, the team has designed two commercially attractive prototypes which are currently in laboratory trials. The protot...MIT material stops bleeding in seconds
...ound, without harming the nearby cells. Even after excess gel is removed, the wound remains sealed. The gel eventually breaks down into amino acids, the building blocks for proteins, which can be used by surrounding cells. The exact mechanism of the solutions' action is still unknown, but the researchers ...Key gene controlling kidney development found
...l at birth. In addition, they produced an abnormal excess in the number of nephrons that in turn produced a useless mass of tissue. Furthermore, the remaining precursor cells underwent apoptosis (cell suicide), further depleting the population of stem cells that could give rise to differentiated cells neede......ntrations of oxygen (hyperoxia), and the resulting excess fluid in the lungs (pulmonary edema), may be controlled by modulating levels of the angiopoietin2 (Ang2) protein, researchers at Yale School of Medicine report in the November 5 online issue of Nature Medicine. The study, which was completed in the ...