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Tag: "excess" at biology news

Migration alert -- How tumor cells home in on the lymphatic system

...n along with data to support it. Tumors produce excess fluid that continually percolates from the tumor towards nearby lymphatic vessels. The EPFL research shows how tumor cells use a clever chemical strategy to exploit this slow, one-way flow in order to migrate to functional lymphatic vessels. As ...

Runners -- Let thirst be your guide

... “The data clearly indicate that EAH is caused by excess drinking during endurance exercise activities, and...o that the kidney can excrete, rather than retain, excess water. But AVP levels can rise in people who exercise strenuously over a number of hours, even if th...

UI anthropologist, colleagues discover remains of earliest giant panda

...pared to the modern giant panda, which averages in excess of five feet in length. Also, like it's modern counterpart, it lived on bamboo shoots, as indicated by wear patterns recorded on teeth and specialized muscle markings, indicating heavy chewing, on the skull. The new find, made about 18 months ago ...

Male circumcision overstated as prevention tool against AIDS

... continent is experiencing an AIDS epidemic far in excess of any other region of the world with some African countries’ prevalence rates exceeding 25% of the adult population and tens of millions dying from the disease on the continent. Talbott’s new study suggests that the reason is that Africa as a whole ...

An 'elegant' idea proves its worth 25 years later

...more nitrogen out and reduces the toxic effects of excess nitrogen accumulation." Excess nitrogen yields ammonia, which is poisonous and in the case of urea cycle disorders, causes brain damage, retardation, coma and even death. Despite the immediate clinical success of the treatment, the drug combina...

A cherry on top: Tart cherries may alter heart/diabetes factors

...liver" measure is important because the storage of excess energy as fat in the liver is a common effect in metabolic syndrome ?and because it feeds the vicious cycle of increased cholesterol and decreased response to insulin that can lead to cardiovascular disease and Type 2 diabetes. Meanwhile, the meas...

Technique monitors thousands of molecules simultaneously

...s, treating it with the receptor, washing away any excess receptor that has not found a key, and then treating the bound receptors with an antibody that recognizes the receptor and is tagged to a fluorescent label. The washing step risks removing a bound receptor if it does not bind the molecular key strong...

UCLA study uncovers clues for why Graves' disease attacks the eyes

...patients?blood. The new antibody binds to the excess receptors on the T-cells, mimicking the actions of..., the thyroid gland goes into overdrive, producing excess levels of hormone that attack the tissue behind the eye, causing them to protrude. In extreme cases...

Cure for cancer one step closer

...-80ºC freezers which have the capacity to house in excess of 164,000 tissue and blood samples. The small sections of tissue collected from patients will be stored in cryogenic vials which will help preserve the tissue's proteins and genetic material almost indefinitely. The Wesley Research Institute i...

Need oxygen? Cells know how to spend and save

...itochondria are designed to produce energy without excess free radical production at normal oxygen levels. Semenza's team noticed that one particular component of the COX protein complex, COX4, comes in two different forms, COX4-1 and COX4-2. Under normal oxygen conditions, the cells' mitochondria cont...

Imaging techniques permit scientists to follow a day -- or four -- in the life of a cell

...cells under a microscope for long time periods (in excess of four days), during which the cells may divide multiple times and cycle through nearly all cellular functions. When coupled with the latest in image-analysis software, this technique allows researchers to gain a long-term perspective on events in ...

Stem cells act through multiple mechanisms to benefit mice with neurodegenerative disease

...inidase ("hex"), used by brain cells to metabolize excess fatty material called lipids. Onset is typically at six months in human infants. The accumulation of lipids in brain tissue destroys the brain cells instrumental in controlling and coordinating body movement and results in inexorable deterioration of...

Bisexual fruit flies show new role for neurochemical

...b team found that glia cells are the source of the excess ambient glutamate. Along with neurons, these poorly understood "support" cells fill the brain. The team discovered proteins in fruit fly glia cells that regulate the amount of ambient glutamate in the brain. Called xCT transporter proteins, they pu...

Saving endangered whales at no cost

...e authors point out that the basic problem of huge excess effort in lobster fishing is characteristic of other aspects of fishing industries around the world--including shrimp and tuna longline industries that expend much more effort than needed to obtain optimal yields, while threatening turtles and non-ta...

Putting an old drug to a new use

...o much iron is bad for our health. Our body stores excess iron in various tissues, where it can lead to organ failure and even death if not treated before irreversible damage has occurred. Researchers from the Innsbruck Medical University, the University of Heidelberg, Germany, and the European Molecular Bi...

Protein sensor for fatty acid buildup in mitochondria

...des the cell energy while reducing the chance that excess fatty acids will accumulate. The St. Jude discovery explains how the fatty acid-sensing enzyme PanK2 tailors production of this key molecule, coenzyme A (CoA), to the cell's energy demands. Understanding PanK2 function is also important because mut...

Natural gut hormone offers hope for new obesity drug

...ed us with a natural experiment that suggests that excess levels of PP over a long period are safe. It does not appear to raise blood pressure or heart rate, or any other obvious side effects." With funding from the Seeding Drug Discovery initiative, Professor Bloom and colleague Dr Caroline Small hope to...

Researchers hot on the trail of brain cell degeneration

...estruction of cells be over-stimulation depends on excess entry of calcium into the cells. Researchers have long been trying to map how cells generate destruction signals in response to the calcium, in the hope of finding new targets for drug design. The object of the study, the Rho protein, belongs to ...

Liposuctioned fat stem cells to repair bodies

...lines, unsightly bulges: people will gladly remove excess body fat to improve their looks. But unwanted fat also contains stem cells with the potential to repair defects and heal injuries in the body. A team led by Philippe Collas at the University of Oslo in Norway has identified certain chemical marks tha...

Killing the messenger RNA -- But which one?

...painful episodes of gout. Similarly, in the brain, excess uric acid can damage sensory neurons and cause deafness. Working with a strain of transgenic mice unable to perform RNA editing and normal control mice, the researchers found that a complete lack of the edited version of the microRNA in question h...

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