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Tag: "evaluate" at biology news

Two NIH initiatives launch intensive efforts to find roots of common diseases

...genes and the environment. We need better tools to evaluate environmental exposures, dietary intake and activity levels, and then to determine how those risk factors interact with specific genotypes to either maintain health or lead to disease. Without these more precise measures of exposure, it will be very ...

New study shows benefit of early therapy in HIV-infected infants

...D4 cell counts in relation to age, and thus better evaluate immune status. They call this age-adjusted CD4 cell count the "z-score." Based on data collected over the past 20 years on infected children born to HIV-1 infected women, the investigators concluded that "children who started their most potent ART b...

Cyclosporine inhibits hepatitis C virus in vitro

... trial between cyclosporine and TAC should further evaluate their observations. "Due to the accelerated rate of disease progression and graft failure after liver transplantation in HCV patients," the authors conclude, "it will be very important to determine the ideal immunosuppression regimen." ...

Gene variation increases SIDS risk in African Americans

...of secondary challenges. We have already begun to evaluate drugs that may mitigate the risk." SIDS -- the sudden and unanticipated death of an infant with no detectable lethal disorder -- is the leading cause of infant deaths in the United States, representing nearly one-third of deaths between one month an...

New licensing agreement to maximize AIDS drug development

...na Faso and two centers in India. The trials will evaluate Ushercell for the prevention of HIV infection among 2,574 adult women at high risk of acquiring HIV. This study will also assess incidence of genital gonorrhea and chlamydia. CONRAD is a cooperating agency of USAID committed to improving reproduc...

New vaccine for condition that kills 500,000 children a year

... increased incidence was so small, the only way to evaluate the safety of a new rotavirus vaccine was to launc...sure of RotaTeq in 50 other countries and plans to evaluate the use of RotaTeq in the developing world. The Merck study appeared in the same issue of the New E...

History of human cannibalism eats away at researchers

...o examine genetic associations with diseases or to evaluate historical patterns of human migration. The prion... identify geographic patterns of variation, and to evaluate selective forces that have potentially influenced these patterns. "In contrast to the previous stud...

'Prosthetic' retinal cells let blind mice see light

... state. Therefore, further studies are required to evaluate what types of retinal degenerative diseases and/or what disease stages are suitable for this potential treatment strategy," they wrote. However, noted the researchers, their technique avoids some problems presented by other approaches to restoring v...

Biomarkers may hone anti-aging therapies

...ers" -- of aging in the skin that could be used to evaluate anti-aging therapies. Their findings are reported in the February issue of the Journal of Investigative Dermatology. "There's a lot of interest in the pharmaceutical and cosmetic industries in developing products that will minimize or reduce certain...

Biodiversity key to sustainable biofuel according to University of Minn. researcher's findings

...he time period of the study allowed researchers to evaluate the average net effects of diversity on resistance to and recovery from drought, pests, disease and other disturbances. Tilman and his collaborators began the work in the early 1990s and began publishing a series of landmark papers in 1994. Biodive...

Heat-shock protein vaccine reduces alveolar bone loss

...resented the findings of a study they performed to evaluate the bacterium Porphyromonas gingivalis heat-shock protein (HSP) 60 as a vaccine candidate to inhibit multiple bacteria-induced alveolar bone loss.Recombinant P. gingivalis HSP60 was produced and purified from P. gingivalis GroEL gene. Rats were immun...

UC Davis study finds HIV hiding from drugs in gut, preventing immune recovery

...dertake the current study in which they set out to evaluate the effect of highly active antiretroviral therapy, known as HAART, on viral suppression and immune restoration in gut-associated lymphoid tissue. They followed 10 patients being treated with HAART, taking blood and gut samples before and after three...

Spray-on skin relieves emotional trauma for child burn victims

... and UQ's Department of Psychiatry collaborated to evaluate the effect of Microskin on the emotional and behavioural functioning of 20 young patients with burn scarring. Department of Psychiatry Senior Research Technician Sarah Swannell said 85 percent of all children reported their scars looked either "muc...

First human trial of antibacterial contact lens

... lens. The comparison involving ten people will evaluate eye health, lens performance on the eye and wearers' subjective responses. Biosignal will announce the trial's results to the market in July. "Adverse events caused by microbial contamination of contact lenses are a major impediment to more conven...

Mosquito spray increases toxicity of pyrethroids in creek, study finds

...e to environmental regulators to reassess how they evaluate a product's toxicity, said Donald Weston, UC Berkeley adjunct professor of integrative biology and lead author of the study. "This interaction of compounds is a whole new issue when doing pesticide risk assessments that has been largely ignored by re...

Stanford snake venom study shows that certain cells may eliminate poison

...s begun in vitro studies using human mast cells to evaluate this possibility. ...

Marine 'dead zone' off Oregon is spreading

...an is "grossly inadequate," making it difficult to evaluate the long-term impacts of low-oxygen and other events. ...

Pest control research leads to pain control discovery

... wrote. She said the present study was designed to evaluate the therapeutic potential of combination treatment with NSAIDs and enzyme inhibitors (a previously undescribed soluble epoxide hydrolase inhibitor or sEHIs) in lipopolysaccharide (LPS)-challenged mice. "We used LPS as an inflammatory agent, which i...

Microscopic passengers to hitch ride on space shuttle

...sults of this experiment will help NASA scientists evaluate the risks to astronauts on future exploration missions planned to go to the moon and Mars. "Spaceflight holds tremendous potential for the development of novel therapeutics, vaccines and diagnostics to treat, prevent and control infectious diseases...

DOE JGI finishes 100th microbial genome

...e of our UMBI faculty members has been studying to evaluate its potential for bioremediation and as an alternative energy source," said Dr. Jennie Hunter-Cevera, UMBI President. "By sequencing this and other important organisms, DOE JGI is helping to accelerate biotechnology discovery and innovation." Micro...

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