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Tag: "evaluate" at biology news

Phenolic compounds may explain Mediterranean diet benefits

...rmation on the utility of the different methods to evaluate endothelial dysfunction," Dr. Pérez Jiménez said. Robert F. Wilson, M.D., from the University of Minnesota in Minneapolis, who was not connected with this study, noted that health benefits of a Mediterranean diet were described over 50 years ago. "...

Eisai announces Phase II data on E7389, a potential new therapy for the treatment of breast cancer

...type of marine sponge. This study was designed to evaluate E7389 as a monotherapy in patients with refractory breast cancer. The primary endpoint of this trial was response rate, measured using the RECIST (Response Evaluation Criteria In Solid Tumors) criteria ?a group of standards used to measure responses ...

Plants, too, have ways to manage freeloaders

..., they will nodulate them, but then the plant will evaluate how much nitrogen it's getting from the bacteria and the efficiency with which it's getting the nitrogen," Simms explained. "If the bacteria are doing a good job, the plant will start supporting it and the nodule will grow. But if the bacteria are no...

'Computer-chemistry' yields new insight into a puzzle of cell division

...y would in the real world -- the researchers could evaluate whether match-ups that looked right when motionless were actually off the mark. "Tiny little shifts can change these things," Rudolph said. The interdisciplinary group's Biochemistry paper, whose first author was Rudolph's graduate student Sohn, co...

MRSA use amoeba to spread, new research shows

...role played by amoeba in the survival of MRSA, and evaluate control procedures accordingly," said Professor Mike Brown from the Department of Pharmacy and Pharmacology at the University of Bath. "Until now this source of MRSA has been totally unrecognised. This is a non-patient source of replication and give...

Combination therapy improves AIDS-related lymphoma outcome

...ndard-risk cohorts with combined CHOP and HAART to evaluate the safety and efficacy of the combined regimen. The investigators found combined therapy improved survival rates for patients with ARL and standard level of risk to rates comparable to those in non-HIV patients with lymphoma treated with CHOP and s...

Computers to save unique type of American red squirrel

...namics in response to different threats, will help evaluate and refocus existing efforts to save Mount Graham Red Squirrel. Although conservation measures are already in place, concerns about the animal's viability have increased as numbers have more than halved since 1999, dropping from 562 to a recent low ...

Satellites show Amazon parks, indigenous reserves stop forest clearing

...ut reserve performance, this study is the first to evaluate the effectiveness of tropical protected areas against forest clearing using quantitative analysis of satellite data. The group used satellite-based maps of land cover and fire occurrence between 1997 and 2000 to compare parks and indigenous lands. D...

Researchers reverse juvenile diabetes in animal model

...on (FDA) approved the start of a clinical trial to evaluate the safety and feasibility of the treatment (Phase 1 trial). The trial is expected to begin sometime this spring and will include at least 15 patients over the age of 18, with type 1 diabetes. Dr. Trucco, director of the Division of Immunogenetics a...

Marine mammals are on the frontline of failing ocean health

... hope their research will help society proactively evaluate the effects and trade-offs of important pesticides and other chemicals before they cause problems in the environment. "As old chemicals are taken out of use, new ones pop up," says Krahn. "Often we don't know if the new substitutes will harm the ec...

New RNAi tools enable systematic studies of gene function

...technology will be a key piece in the puzzle." To evaluate the RNAi library's performance, the scientists sampled a subset that targets approximately 1,000 human genes. They systematically inactivated these genes in a human cancer cell line to identify ones that regulate cell division during malignancy. Auto...

First wolverine radio-collared in Pacific Northwest

...dative, Aubry and his team quickly went to work to evaluate the health of the animal, take measurements and tissue samples for genetic analyses, and install a radio collar to report her movements to Aubry via satellite for the next 18 months. "With this technology, we can now begin to gather reliable informa...

Scientists design potent anthrax toxin inhibitor

...owing the disease process to begin. They also will evaluate the inhibitor with and without adjunct antibiotic therapy. ...

New hybrid virus provides targeted molecular imaging of cancer

...international collaborative research team plans to evaluate the safety and efficacy of other hybrid vectors in animal models. The ultimate goal is to adapt and optimize the AAVP-based targeting prototype for use in patients. ...

Researchers develop portable 'vein finder' for faster, more accurate injections

...Hospitals have sophisticated ultrasound systems to evaluate the heart, valves and vessels for general blood-flow studies. But this kind of equipment is impractical and too costly for field use. "Although the use of Doppler technology isn't new, the novel aspect of our vein finder is the system's design, whic...

Curry and cauliflower could halt prostate cancer

...cancer," Kong said. "So we undertook this study to evaluate how effective PEITC and curcumin might be ?individ...duced even stronger effects. The group went on to evaluate the therapeutic potential of curcumin and PEITC in mice with well-established tumors, and the result...

Gene-specific Ebola therapies protect non-human primates from lethal disease

...ve when administered after infection. To further evaluate the efficacy of the three-PMO combination, four rhesus monkeys were treated with the drug two days prior to Ebola virus exposure. Three of the four were protected from Ebola infection. "These results, while preliminary, are very encouraging," said C...

Less antibiotic use in food animals leads to less drug resistance in people, study shows

...n the other countries' food animal production. To evaluate whether the country's restrictive antibiotic policy has affected bacterial drug resistance, Australian researchers examined C. jejuni isolates collected from 585 patients in five Australian states. None of the patients had received fluoroquinolone tr...

U of MN researchers develop way to visualize synchronized interactions of nerve cells in the brain

... "This discovery will allow researchers to better evaluate the brain function of people with various diseases...ey take seconds to detect activation. To better evaluate how the nerve networks in the brain communicate and interact with one another, researchers used magn...

Anti-HIV drug has potential to prevent transmission in women

...safety and product acceptability study and did not evaluate if the microbicide would be effective in preventin...e the way for further studies that will ultimately evaluate whether the gel protects women from HIV infection," says co-author Lisa A. Maslankowski, MD, medical...

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